Plum I have the Oskia super 16 serum. I use it in the morning (and LRP Redermic in the evening). I was seduced by all the hype, but imo it hasn't been worth it. It smells nice, but for the first few times I used it, it made my neck itchy and sensitised. That has reduced, but in the 2-3 months I've now used it, I haven't noticed a perceptible difference that I can attribute to this serum. I have much better results from alpha h serums, which are half the price. However after 2 months I'm still only 1/4 through the bottle, so it has lasted well, and hasn't broken me out. I won't repurchase - but of course that doesn't mean it won't work for you! And it might well be having anti ageing effects that are preventative, who knows..