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"How the case against the MMR vaccine was fixed"(42 Posts)
An article in the BMJ that you might find interesting.
That's the actual title of the article, in the British Medical Journal. I'm not trying to up the controversy at all.
How the link was fixed
The Lancet paper was a case series of 12 child patients; it reported a proposed new syndrome of enterocolitis and regressive autism and associated this with MMR as an apparent precipitating event. But in fact:
-Three of nine children reported with regressive autism did not have autism diagnosed at all. Only one child clearly had regressive autism
-Despite the paper claiming that all 12 children were previously normal, five had documented pre-existing developmental concerns
-Some children were reported to have experienced first behavioural symptoms within days of MMR, but the records documented these as starting some months after vaccination
-In nine cases, unremarkable colonic histopathology resultsnoting no or minimal fluctuations in inflammatory cell populationswere changed after a medical school research review to non-specific colitis
-The parents of eight children were reported as blaming MMR, but 11 families made this allegation at the hospital. The exclusion of three allegationsall giving times to onset of problems in monthshelped to create the appearance of a 14 day temporal link
-Patients were recruited through anti-MMR campaigners, and the study was commissioned and funded for planned litigation
Shorter summary here.
In multiple ways, the story of the Lancet article was crafted to support the conclusion Mr. Wakefield hada conclusion he came to before starting on the research project.
Another useful BMJ article.
Clear evidence of falsification of data should now close the door on this damaging vaccine scare
I have also just read this and was about to start a post and saw that TA had posted.
Am interested that no-one has an opinion
I had always thought AW's research was poor and with some incredible conflicting interestfrom his point of view, but this article made my jaw drop even further
He misreported the findings, he was fraudulent.
I have my personal opinions but I shall leave these out now
I think maybe finally people are fed up, bored, and placed in a state of ennui by furhter conversations about MMR
it has gone on too long
it is no news
it is dull
But people still worry about the MMR
And having it
And all other vaccines
He has left this inheritance and he was a fraudster
ok, I'll bite.
he was not a fraudster.
he did not falsify data, nor misrepresent anything.
there have been some very interesting rebuttals of that article - but I guess you're not interested in those.
mmr remains safe for the majority. but his work was, and is, very interesting.
there are osme very ill children out there, not getting the help they need because of the blanket denial that mmr is anything but 100% safe fo reveryone, all of the time.
sorry, hit post.
i mean go on, let us know your thoughts on why
tbh, I would have agreed with the op until I started reading posts on this forum from mothers who said their lo stopped walking or talking for a few days after, had extreme reactions, leg pain for weeks, etc. even though the majority of these stories have a happy ending, these are accounts from women we "know" who have no reason to lie.
after reading these stories I have changed my mind about the mmr and decided to go for the singles.
The main problem, is that most people are not interested in the actual facts, only the "facts" as presented by the media.
Eg, in the years after his initial finding, linking the MMR vaccine to bowel disease and autism, Wakefield published another 19 papers on the vaccine-induced disorder.
All were peer reviewed. However, strangely enough, none of these 19 papers are ever discussed in the media. The only study that keeps seeing the light of day is the original study from 1998, along with the original questions about conflicts of interest, (which have been explained, in great detail, several times)
This is very interesting indeed, because not only has he continued his own studies, but since then, a large number of replication studies have been performed around the world, by other researchers, that confirm his initial findings.
its been replicated in Canada, in the US., in Venezuela, in Italy but they never get mentioned. All you ever hear is that no one else has ever been able to replicate the findings.
Well, this is from the Autism Speaks Official Blog, a very scientifically-oriented organization:
"Any link between vaccines and autism? Put this issue to rest once and for all, one way or the other?
December 21, 2010
We really wish it were that simple. Several epidemiological studies have explored whether either the MMR vaccine or thimerosol, a preservative previously used in vaccines, are linked to autism, and these studies have not supported a link. However, these studies were not designed to identify effects in a small population of potentially vulnerable children due to rare genetic and/or medical conditions. We are seeking to understand if vulnerable populations exist, and if so, how we identify them early so they can be protected from public health threats in the safest manner possible. For more information please see our vaccine statement and an interview with Dr. Geraldine Dawson, Autism Speaks Chief Science Officer, about vaccines and autism."
Darrell, read this thread from www.boards.ie
Plenty of opinions here.
Just to add to this fine thread my favourite Brian Deer quote and of course the Film he was refering to ..
"At all times outside the GMC I have been videotaped . none of that video tape has ever been shown . Because it reveals me discussing and debating issues with people who raise them with me to my undoubted credit."
How did a journalist come to be so involved in all of this?
I first watched that video a few weeks ago and I assumed he was a medical man. I was
struck dumb a little surprised to find out he was a journalist.
"How did a journalist come to be so involved in all of this?"
The person who commissioned Deer was Paul Nuki, Sunday Times' sometime Head of Newsroom investigations and "Focus" editor. Paul Nuki is son of Professor George Nuki. Professor George Nuki in 1987 sat on the Committee on Safety of Medicines when the CSM was considering Glaxo company Smith Kline & French Laboratories' Pluserix MMR vaccine for safety approval.
Pluserix was withdrawn in the UK in 1992(overnight) as it was cause Mumps Meningitus
Paul Nuki now runs NHS Choices ...
Deer actually a philosophy Graduate and has no medical qualifications. what astounds me is how the persion who raised the initial complaint with the GMC can atttend the hearing in the public gallery, not be called as a witness and them report on it in the Times and BMJ and get paid.
Aha. Now I've Googled Nuki and Deer, all is becoming clear. To find a story rather than to investigate an existing one? Hmm.
I think this is quite interesting..
one day the world will wake up, actually check the "facts" that Deer spouts all the time, and realise he is just full of lies...
....and on the back of that documnt release, Wakefield is now publicly asking for a full retraction of the BMJ/Deer article.
this could all get very interesting indeed...
do you now, it's funny - have just searched for a "proper" news link to that, and no reports
now, isn't that odd?
How do you find this stuff?
Perhaps it could be printed in The Sunday Times?
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