Firstly, rabbits really need the company of other bunnies as they are generally social creatures. Rabbits also must be neutered for health reasons and need annual vaccinations, so you have to factor in those costs. Another important consideration is what will you do if you go away? This can be especially difficult with house rabbits as most rabbit boarding facilities house the buns outdoors which would not suit a housebun. Just a general point, a lot of people get rabbits mistakenly thinking they are lovely fluffy, cuddly creatures. They are fluffy, but not especially cuddly and most hate being handled. They can kick and scratch if they really object. They do like to be stroked but usually only on their terms, i.e. With all four paws firmly on the ground. Remember also that they can live up to 10 years.
A housebun can be very destructive. You need to consider how rabbit proof your home is. Rabbits will chew wallpaper, carpets, any electric cables they find, furniture etc. They are very chewy creatures. Unless neutered they have a tendency to spray their urine (esp. Males) which is a lovely brown colour and really strong smelling. They need a lot of space and plenty of hours where they have access to that space. A housebun should not spend most of its time shut in a cage with just a small amount of run time. They need hay to nibble and that has a smell you may not like in the house. Also they moult - you'll spend a lot of time hoovering fluff up and will find fluff everywhere.
On the plus side, they can be litter trained with a bit of patience. They can also be trained to obey commands if you have enormous patience and time to spare with them. They are very funny when they do mad runs round. They also seem to be obsessed with cookery programmes (at least the ones I've had have been). If you're prepared to put the work in, they can be very rewarding but it does take a lot of time to train them to behave appropriately inside.