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Get updates on how your baby develops, your body changes, and what you can expect during each week of your pregnancy by signing up to the Mumsnet Pregnancy Newsletters.

Get updates on how your baby develops, your body changes, and what you can expect during each week of your pregnancy by signing up to the Mumsnet Pregnancy Newsletters.

Pregnancy

Had CVS today, result hopefully tomorrow, please hold my hand

18 replies

AncientHagwithbump · 20/08/2009 22:35

I am 10+ weeks pregnant with #4, have had 4 MMCs in the past, have known genetic problem that predisposes me to certain trisomies... oh, and there is the small matter that I am 43. I am scared and feeling that I am pushing my luck and as if the fact that I had 3 healthy DCs already means I am "due" a affected child. Irrational, I know, but there you go .
CVS today was my 3rd, they needed 2 attempts, it was jolly painful (more so than the previous ones), but I have been fine since albeit slightly bruised feeling. DH is waiting on me hand and foot .

So, please send positive vibes our way. BTW, have namechanged for this because pregnancy is not yet public knowledge and know MNers in RL.

OP posts:

Report

discojen · 21/08/2009 00:27

hand-holding activated

<br />
Hope everything is ok<br />
x x x

elkiedee · 21/08/2009 00:42

Hope all is well.

verylittlecarrot · 21/08/2009 01:02

Holding your hand too. Understand and sympathise. Hope your results are completely reassuring.

nappyaddict · 21/08/2009 03:40

Good luck

duchesse · 21/08/2009 03:45

AncientHagwithbump · 21/08/2009 08:20

Thank you for all your messages.
I went to bed just after I posted as I had been trying all evening NOT to post telling myself looking for good wishes from people I do not know is too needy for words . Who was I kidding? - I am needy!

Anyway, so far so good this morning. Feel a bit bruised at the site where they went in, but no bleeding, no pelvic cramp etc. Mobile is fully charge and will not leave my person today until I hear.

Thanks again for all your good wishes.

OP posts:

elkiedee · 21/08/2009 09:00

Thinking of you still, that kind of waiting is dreadful, and I may yet try to go through it all again.

NumptyMum · 21/08/2009 13:19

I hope it all goes well for you, the waiting is so difficult. The weekend approaches, so can you go out (gently!) with your other DCs as distraction? Positive vibes from north of the border...

AncientHagwithbump · 21/08/2009 19:21

46 XY!!

I am so happy and excited: 4 boys, oh help!

Thank you for the moral support, made all the difference.

Now I only have to survive telling my mother and, oh Lord, my work....

OP posts:

ZippysMum · 21/08/2009 19:23

Congrats! And way to go with being able to use those hand-me downs !

NumptyMum · 21/08/2009 19:50

I'm so pleased! Phew, now you can just sit back and grow .

grin · 21/08/2009 19:56

Well, AncientHag, you just made a fellow pg have a tear in her eye with your good news. Good work

HerbertSnodgrass · 23/08/2009 00:01

Ancienthag, what wonderful news! Congratulations!

May I ask a question, please? Do you know what method the lab used to provide you with the results so quickly? How did they get to a chromosome count within a day? I have had some frustrating experiences with a lab where they have told me it is an impossiblity to get my results so quickly. I want to talk to them about the possibilities that appear opn to other labs but not to them.

Thanks!

LightningBolt · 23/08/2009 00:13

CongratulationsI have a child with genetic malformation that was compatible with life and wouldn't be without her but it is lovely that your dc is without any issues.

PacificDogwood · 23/08/2009 10:34

Herbert, I was told the lab do a so called "direct preparation" first and do a QT-PCR from that. That allows them to check for trisomies, translocations (which is my issue) and gender. I was promised a result within 48 hrs which would have been Monday (tomorrow) but as before they phoned @ 4pm the day after I had the test done (Thursday morning).
The cells are now being cultured and a full karyotyope of all chromosomes will be done from that. That result should be available in 10-14 days and I will get in writing. As this was my 3rd CVS I am not too worried about this as my major concerns (particularly trisomie 13 = Patau syndrome) have been addressed.
It is may understanding that cells obtained via Amniocentesis always need to be cultured and that the result takes longer because of that.

Lightning, thank you for your congratulations.

EColi · 23/08/2009 10:51

Direct preparations from CVS are only suitable for chromosome counting (ie. you can count 46 chromosomes and identify the x and the y chromosome) but cannot be used to rule out other chromosome abnormalities. Since the same information can be gained by 2 other methods - QF-PCR (tends to be carried out in the London area) and FISH (tends to be carried out elsewhere) and these two methods are a lot cheaper to do than a direct prep, most labs do not get funded to do direct preps anymore.
Amniotic fluid cells can also be tested by QF-PCR and FISH (again, for chromosome number (trisomy) and for number/type of sex chromosomes only) but must be cultured to provide any other information.

PacificDogwood · 23/08/2009 11:10

Ah, yes, FISH was mentioned too, but they did do direct prep, hence early result, thankfully!
Thanks for the more competent info, EColi ( at your name, should you not change it to H1N1??)

EColi · 23/08/2009 12:50

but if i changed it H1N1 I would get put into isolation for a week
Glad you got a good result (and your lab is funded for direct cvs tests!). Enjoy your boys

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