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Aspirin in early pregnancy - does it reduce or increase risk of early miscarriage?

20 replies

Emwils · 10/12/2020 11:12

Hi everyone, I hope somebody may have some thoughts to share on this one...

I've had two early MCs this year - one in March, one in June, both between 6 - 7 weeks. I'm really pleased (and also terrified!) to be pregnant again now (4+2 so very early days still - fingers crossed!). If this pregnancy succeeds it would be our first DC. I'm 35.

As the NHS wouldn't refer me for miscarriage advice until I'd had 3 miscarriages I decided to seek help in the private sector, and saw a private ob/gyn. She has prescribed dispersible low dose / baby aspirin daily, along with daily cyclogest pessiaries. I've seen so many positive stories on here indicating that baby aspirin may help women who've suffered from previous MCs to carry pregnancies to term, and it seems to be a fairly standard course of treatment. However, I've also come across a few rather alarming references via Dr Google, which indicate baby aspirin may in fact INCREASE the risk of early MC?! I've pasted two of these references below:

If you need to be on aspirin, it should not be started before 8 weeks
of pregnancy. There is evidence that taking aspirin whilst trying to
conceive and before 8 weeks of pregnancy will have an adverse
effect on implantation. For this reason we recommend that you do
not take aspirin unless a recurrent miscarriage practitioner has
advised you to do so. (mft.nhs.uk/app/uploads/sites/4/2018/04/12-123-Recurrent-Miscarriage-Service-January-2015.pdf)

Recent evidence suggests that Aspirin may increase the relative risk
of early miscarriage and for this reason clients are now advised to
stop low-dose Aspirin just before embryo transfer and not to take it
in early pregnancy. (www.zitawest.com/wp-content/uploads/2015/06/Reproductive-Immunology.pdf)

So basically I am now very confused about whether to take the aspirin after all - will it help in my situation, or will it potentially make things worse?! Needless to say I've asked my doc this question too, but she only works in private practice one day a week so I may not get a quick response...trying not to panic, but I'm so worried about potentially losing this baby because of taking or not taking something incorrectly, i.e. whether or not I lose this baby could be preventable :-(

Any thoughts, experiences (or advice from your own doctors) would be very welcome - thank you ladies :-) x

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Starlive23 · 10/12/2020 12:27

Stay away from Dr Google OP and if you trust your doctor and she seems good ie not a sort of cowboy doctor, then I know it's hard but try to trust her.
Most early miscarriages are caused by chromosomal issues and if you have any questions you could always give EPU or midwife a call.
It's so, so hard not to google. But it can cause untold levels of anxiety throughout the whole pregnancy. Good luck with the pregnancy op x