Anyone aking clexane, prednisolone and cyclogest?

[Dropdeadfred]

Just wondered if there were any pregnant ladies on here taking any of the listed medication ??? if so..what have been your experiences?

[ALittleLemonTwist]

I am currently taking clexane injections (alongside low dose aspirin) after 3 consectuive miscarriages. Whilst not pleasant, it is over in seconds and apart from some brusies I have had no side effects.

HTH!

[FrostyPhlebas]

I am (also aspirin & high dose folic acid) - I have mildly elevated anticardiolipin antibodies, anti progesterone antibodies & NK activity.

I'm on pregnancy #10 (currently 12+2) with 3 live births, 2 mid trimester losses & 4 first trimester mcs. Live births have been from pregnancies I've had this treatment in, mid trimester losses happened when I had anticoagulants but not steroids (in one case I had IVIg & had a massive immune flare :( ), first trimester losses were no treatment or aspirin only.

I come off pred/cyclogest at 12-14 weeks, aspirin (150mg which is double accepted mc dose) & clexane are continued to 24 hours before delivery which is at 37-38 weeks by elective c-section. I have scans and see obs every two weeks throughout the pregnancy & have dopplers for placental function from 24 weeks every 4-6 weeks.

Treatment is on the NHS btw - initially I went to ARGC for testing but managed to persuade my NHS consultant to treat me on the basis of my history really rather than test results (she feels that 4 first trimester losses is abnormal & one, let alone two, mid-trimester losses is very abnormal - even without evidence from trials my history speaks for itself).

[Dropdeadfred]

Thank you both for your replies....as you are both pg now could you tell me if you feel any differnt being on medication at all?
Does the progesterone give you pg symptoms?
Sorry for your losses btw - i have a history oof recurrent miscarriage bu I am lucky enough to have 3 dds.

[FrostyPhlebas]

prednisolone is horrible - hunger, weight gain, hair growth, , insomnia - always v. happy to come off it (on plus side it helps with the nausea).

clexane - sometimes stings & bruises but no other effects

progesterone - only side effect I get is bloating.

[ALittleLemonTwist]

Yep - I'm 6+3. Early days but we saw a heartbeat at an early scan this morning so hopefully that is a good sign.

Don't feel any different being on clexane, only having very mild pg symptoms - slight nausea and tiredness but that's it

[Dropdeadfred]

thanks again...i will now admit to being 5w6d pg..and taking all 3 medications
I have no real symptoms aprt from tiredness and sometime i think my boobs are ender...but both of these could be down to the progesterone i've read....

[rubybambini]

Hello. Been taking pred since May this year - 60mg, then a taper to current level of 10mg a day. It completely masked my pregnancy symptoms - was 12 weeks before I knew! All seems well from tests and scans, so I'm probably no more worried than the next mum to be.

I stay on the pred til our baby is born, as the risk of taking it is 'better' than the risk of my kidney problem returning.

That's a very low dose, and no side effects to report, but on 60mg - different story! Insomniac but euphoric at the same time. Moon face too - yuk.

HTH in some way.

[Dropdeadfred]

Thanks Ruby ... and congratulations x

[Dropdeadfred]

Well.... Sorry to say that even with all that medication this pregnancy failed too... I knew my boobs had completely deflated when I woke up yesterday morning but I tried to be hopeful... Awful back ache and bleeding started last night... I dint know what to do now.. Give up?

[rubybambini]

Oh no. Very sorry to read that x