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STEROID PREDNISOLONE PRESCRIBED WITH IVF

(15 Posts)
Gina350 Wed 04-Jul-18 23:53:31

Hi all, I would like to hear experiences of the steroid Prednisolone being prescribed for high thyroid antibodies in the blood during iVf for better embryo implantation. I have been warned about the risks to the baby however it seems like the DR thinks it will give the embryo the best chance of successful implantation. I am really confused as there isn’t enough evidence on success rates and risks. If anyone has used this and has a story to tell, either positive or negative please reach out.
Thank you very much!

Filipinam Thu 05-Jul-18 17:57:53

I was on it durong my 3rd cycle and got BFP first time in my life however it then turned into BFN after 3 days...

Bettyboop82 Thu 05-Jul-18 20:23:36

Hi, I got my first ever BFP (twins!) using prednisolone after 5 years ttc and 3 previous failed ivfs. My twins are perfectly healthy at 28 Months dnd my pregnancy was a breeze! Good luck!

Bettyboop82 Thu 05-Jul-18 20:24:41

18 months I mean! I told 20mg of pred from transfer until 12 weeks then weaned off

Jenbot78 Thu 05-Jul-18 21:01:26

I had (have) very high antithyroid antibodies. I had one IVF that ended up in a CP and then one with prednisone that ended up in my daughter who is 1. Off for a FET hopefully next month with pred again. I think it’s why I got pregnant but maybe it was a fluke! We’ll see next month!

Jenbot78 Thu 05-Jul-18 21:05:43

This is useful : www.thyroid.org/patient-thyroid-information/ct-for-patients/volume-8-issue-3/vol-8-issue-3-p-5-6/

Gina350 Fri 06-Jul-18 08:09:18

Thank you very much for this information to everyone. I found the read up that Jenbot78 posted extremely helpful. It has given me more confidence and answered my questions. Thanks again. Please do keep posting your experiences if you are going through similar situation.

Jenbot78 Sun 22-Jul-18 16:16:17

No worries, glad it was helpful! Am shortly starting a FET with steroids again. I don’t love being on them, they make me hungry and put weight on. But I will grit my teeth and get through it! Good luck!

Nixwix Fri 11-Jan-19 09:20:51

Hi everyone.

I know this is a late post but I am currently going through IVF. I had a miscarriage in Oct 2017 (thyroid antibodies were negative) and then an ectopic pregnancy, resulting in removal of my left tube last year in Feb. I recently tested my thyroid panel and I tested positive for thyroid antibodies. Dr has mentioned Prednisolone to me and also intravenous lipids infusion. What did you guys decide in the end and what’s your opinion? I am on my last day of stims so any advice would be helpful and very kindly appreciated!!

Thank you!

NV42 Sun 13-Jan-19 06:23:50

Hello Jenbot78

May I ask what is CP and FET?

I have thyroid antibodies and I was prescribed 25mg prednisone which I am worried to take as I read that it has phychotic side effects, palpitations etc.

I already suffer from palpitations, chest pain due to reflux issues and the last month it has triggered a lot of panic attacks so I am scared to death to take 25mg predisone.

They want me to start one week from starting the Gonal - F injections and if I get a BFP then continue them during the first 3 months of pregnancy.

May I ask what was your dosage and when they asked you to start them and end them?

NV42 Sun 13-Jan-19 06:24:20

Hello @Jenbot78 (forgot to actually tag you smile)

May I ask what is CP and FET?

I have thyroid antibodies and I was prescribed 25mg prednisone which I am worried to take as I read that it has phychotic side effects, palpitations etc.

I already suffer from palpitations, chest pain due to reflux issues and the last month it has triggered a lot of panic attacks so I am scared to death to take 25mg predisone.

They want me to start one week from starting the Gonal - F injections and if I get a BFP then continue them during the first 3 months of pregnancy.

May I ask what was your dosage and when they asked you to start them and end them?

NV42 Sun 13-Jan-19 06:27:48

*@Gina350*, @Filipinam What is the dosage they have given you and when do they want you to start them?

@Gina350 have you started the steroids yet? If yes, good luck!

Rememberallball Sun 13-Jan-19 06:48:09

I take 10mg prednisolone daily (was 5mg but ivf clinic asked advise of rheumatologist - I have RA after my previous failed cycle) and was advised to take an additional 16mg for 5 days pre embryo transfer - this is the clinic’s standard protocol). I have, in the past, been on 40mg daily while ill with my asthma and, apart from increased appetite and feeling as if I’ve drunk 3-4 double espresso’s, haven’t had palpitations. So it’s not a given you’ll get them!!

TinyPaws Sun 13-Jan-19 14:41:19

I requested this during my last IVF cycle, clinic said no, I had a chemical pregnancy/early miscarriage and regret not pushing harder/finding a different clinic.

GG2233 Tue 15-Jan-19 01:25:19

Message deleted by MNHQ. Here's a link to our Talk Guidelines.

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