It is hard to stop when you have been on the rollercoater for so long. I am 43 and the doctors still keep telling me I am too old, I have concieved 10 times in the last 3.5 years, and they still tell me my egg reserve is low!!!! I have spent the last few months believing that it is too late, and giving up, but now I am starting to wonder if I have enough strength to fight again. So I am not really a good person to talk to about giving up, as I find it so hard. It is easier for me to carry on trying than to let go of that one last attempt!
I think if you are going to give up on ttc, then it is important to have something else to fill in the gap that trying has taken. Something new to occupy your time and your head!
The famous tertia once said, you know when it's time to give up because the pain of going on is now worse than the pain of giving up. that point is different for everyone. IVF has a lot better chance than clomid (which for many ppl is worse than useless as it's an oestrogen inhibitor). Are you sure odds are 1/10? For your clinic or your particular diagnostic pattern?