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I can remember ulcerated bottoms on at least one of mine (fortunately for them I don't remember whose bottom so can't name and shame!) - I think we struggled through on Sudocrem and Vaseline combined but it was hideous.
Poor DD2. Can you leave it bare for any length of time?
poor mite ds had a bout of nappy rash a little while ago (not this severe) and someone recommended chammomile tea i know it won't clear a bad case up but perhaps it would be soothing to gentle bathe the area to try and make her more comfortable whilst the other stuff does the trick
YG, I don't know if it would help your DD right now but we found 'morhulin' to be a fantastic barrier and healing cream for DD2's bum. She's got eczema and this is the one single cream we have found works to prevent and heal nappy rashes, blisters, etc.