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Antihistamines. Has anyone ever found one that is truly non drowsy?

(51 Posts)
Greyspots Sun 09-Jun-19 18:29:14

I know the modern ones are supposed to be better than the old ones but I think I'm just very susceptible because I always end up over-sleeping and zoned out when I have antihistamines.

Has anyone had similar problems and found one which is better? I feel like I've tried most but am willing to have another go if one is recommended.

Luscinia Sun 09-Jun-19 18:39:55

Loratadine. Fexofenadine.

bedtimestories Sun 09-Jun-19 18:45:04

I Love fexofenadine (hope I've spelt that right

Myotherusernameisshy Sun 09-Jun-19 18:45:34

I’ve never had a problem with loratidine. With all of them the drowsiness is supposed to be a temporary side effect which stops happening after taking for a couple of weeks.

BryanAdamsLeftAnkle Sun 09-Jun-19 18:47:56

Fexofenadine. It's a god send

Greyspots Sun 09-Jun-19 19:00:00

I know I have had problems with loratidine.

Something with side effects that stop after a while doesn't work because I take them sporadically throughout the year when I come into contact with triggers rather than just for hayfever.

Is fexofadine prescription only? I'll speak to the doctor.

Greyspots Sun 09-Jun-19 19:00:37


DonPablo Sun 09-Jun-19 19:00:56

Fexofenadine.... Its changed my life.

DrinkFeckArseGirls Sun 09-Jun-19 19:02:46

Another vote for fexofenadine. In the UK it’s prescription only.

RandomMess Sun 09-Jun-19 19:06:41

I thought you could get 120 strength OTC at pharmacy and 180 strength was prescription only?

I think it always comes down to you as an individual though whether you feel side affects.

ThePerturbedPenguin Sun 09-Jun-19 19:07:52

My fexofenadine always makes me drowsy!! What dose and what time of day do you take it?

Myusernameismud Sun 09-Jun-19 19:08:07

It's the third time I've said this today, but Fexofenadine is the God Tier of antihistamines. Prescription only, but GPs are usually happy to prescribe it over the phone.

And, again I keep bleating on about it, but sinus rinses are a life changer. Yes it feels weird, but just try it grin

RandomMess Sun 09-Jun-19 19:10:21

It's a long lasting one so I guess take it early evening and give it a go for a few weeks to see if you get used to it?

Non of them make me drowsy 🤷🏽‍♀️ think I'm a freak...

Myusernameismud Sun 09-Jun-19 19:11:19

I take 180mg first thing in the morning, for
a million various allergies. If I have a reaction to something (nearly always mustard, the sneaky bastard hidden in so many things) I'll take another if it's later in the day, but that's on allergy specialists instructions so not something I'd recommend anyone else does.

MsMightyTitanAndHerTroubadours Sun 09-Jun-19 19:17:05

I am okay with loratidine and certirizine, although thinking about it I am doubling up atm (one AM and the other PM) and I slept right through for ten and a half hours!

I haven't taken Piriton for years as that used to really knock me out!

INeedNewShoes Sun 09-Jun-19 19:18:26

I'm lurking to see the responses really but I'll also add that I was on Ceterizine (sp?) and Loratadine long term (taking 2 daily on the instruction of my immunology consultant with top ups if needed) and I was TIRED (think literally falling asleep at my desk and not being able to help it).

Due to another medical condition I was put on an immunosuppressant and that had the wonderful side effect of dampening my allergies so I was able to stop the antihistamines and the tiredness lifted, so I am also firmly in the camp of believing that some 'non-drowsy' AHs do have a drowsy effect, at least on some people.

Myusernameismud Sun 09-Jun-19 19:29:47

Having said that, I am tired essentially ALL the time (I'm talking could have 2 naps a day and still go to bed at 8 kind of tired) so maybe it does make me drowsy and I just haven't noticed hmm

Iamthewombat Sun 09-Jun-19 19:31:54

I’m with Newshoes. I only need anti-histamines for 3-4 weeks a year (ash pollen) and both cetirizine and loratidine knock me for six. I’ll be asleep at my desk by mid-afternoon, guaranteed.

I work in financial reporting, though. Maybe that contributes!

DrinkFeckArseGirls Mon 10-Jun-19 14:09:14

I fall asleep due to allergies if I don’t take anti-histamines so the meds perk me up!

BlackAmericanoNoSugar Mon 10-Jun-19 14:14:09

Loratadine used to be fine for me and then one year my response changed and I was drowsy to the point that I wasn’t safe to drive. I have a prescription one now called Drynol, active ingredient bilastine, which is excellent and doesn’t cause any drowsiness.

SleepyTraveller Tue 11-Jun-19 21:38:16

Acrivastine works for me (the short-acting version of Benadryl)

Sparklypen Tue 11-Jun-19 22:46:50

Beconase nasal spray plus eye drops.

MrsMoastyToasty Tue 11-Jun-19 22:49:51

I take ceterizine (?) hydrochloride. It seems to work for me, but then again I take it at bedtime so drowsiness isn't an issue.

Alabasterangel6 Tue 11-Jun-19 22:51:30

Another for acrivastane. It’s the old one which ironically has more of a supposed drowsy risk but it’s the opposite for me. Loratadine and certrezine knock me bandy but acrivastane doesn’t.

To my knowledge it is only sold under the brand name of Benadryl and you can’t get any cheapy own brand equivalents though which makes it expensive.

If I do have to take cetrezine I fine the optimum time to be about an hour before bed so the worst of the fug is overnight but it does make getting up tricky.

Linnet Tue 11-Jun-19 22:54:38

Cetrizine knocks me out as does piriton. Loratadine does absolutely nothing for me.
Last year I saw a thread on here where someone suggested fexofenedine, so I went to the drs and asked for some. It has changed my life, I can breathe, I’m not sniffly or itchy it’s amazing. I recommend it to everyone, it’s great. I wish I’d known about it years ago.

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