Fluoxetine and alcohol - does it make you feel really down?

[BobDowne]

I've been taking 20mg of fluoxetine a day for about a year now after a nasty separation.
Recently i've started to have a bit more of a social life, so have been drinking more alcohol.
I find the next day i've often been feeling very down and tearful, even when i had a really enjoyable night out, so there's no real reason for it.

Does anyone else find this? I know alcohol is a depressant, wondered if i should avoid it altogether whilst on the ADs.

[WigWamBam]

It's usually recommended to avoid it altogether whilst on ADs, although some people manage to have the odd drink or two without any great problem.

As you say, alcohol is a depressant - but it will also make your fluoxetine less effective, so might make you feel down and tearful.

[whateverhappened]

I found at first it made me feel awful - for bout the first couple of months. Now I generally stick to just two glasses of wine a night, generally only once a week, and I'm fine with that. If I drink more I usually feel pretty low afterwards.