Has anyone ever tried the supplement SAMe for depression/anxiety?

[AprilDHarvey]

In the past, I've taken fluoxetine which didn't work for me for various reasons and St Johns Wort which I found to be pretty ineffective. I've recently been reading more and more about the effectiveness of SAMe and was wondering anyone here had any experiences of taking it?

[scortja]

I haven't (yet) but am going to start 5HTP in the next week...

Have you tried high doses of Omega 3? I am doing pretty well at the moment - usually I would be back on ADs by now... (I have been on and off ADs for 20 years - all my adult life)