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Zolpidem and other meds when pg

(5 Posts)
UpsyDaisyDo Fri 03-Dec-10 21:11:56

Does anyone have any experience or know if its ok to take sleeping meds (zolpidem, clonazapam and quetiepine) when pg? I've just found out this week and don't have an appointment with gp until next weekend.

The last two nights I've just taken half (5mg) of zolpidem and 50mg of quetiepine but have had such crappy nights sleep that I now feel hideous.

I've posted about coming off the meds before but not managed it - but obviously now its more of a priority

snowmash Fri 03-Dec-10 21:45:31

You can try NHS direct...or ask if your GP surgery will do a phone consultation?

There are some drugs that can cause bad effects/rebound in some people if you just take yourself off them, so it's a difficult balance.

Be thinking of you.

fluffybitingguineapigs Fri 03-Dec-10 23:32:35

Hi Upsy

I took some zopiclone while pregnant (approx 30 3.75mg tablets during the whole pregnancy) and was on haloperidol at night as was diagnosed with bipolar while pregnant.

I was on roughly one 3.75 tablet per night before pregnancy but was able to reduce that by firstly cutting or snapping the tablets into two and then quarters, and by allowing myself to take zopiclone only every other night and then only when needed (rarely).

I was referred to a specialist perinatal team who were very knowledgeable about medications and risks for mental health drugs in pregnancy. I was really concerned about having medication in pregnancy but they were able to print off medical literature which gave the risks compared to the baseline for me to make up my mind.

There is a risk in taking anything while pregnant, (and this risk depends on the drugs and the quantity you are taking - and doctors would not prescribe you anything that absolutely is unsafe in pregnancy), but this also has to be weighed up against your wellbeing and the wellbeing of your baby as your stress hormones do also cross the placenta as well as any drugs.

I am currently on Seroquel and have asked my MHT about what would happen if I wanted to ttc and they said that i could either stay on it, come off all medications or choose an older type antipsychotic - not because seroquel is unsafe but there is more data available for older drugs. For ethical reasons no drugs company will trial drugs on pregnant women, obviously.

Your seroquel doesn't sound very high - but if you are worried you do need to speak to a mental health team - preferably one that has experience with perinatal health.

Fwiw just to put things into context, my psychiatrist told me that the risk of any defects in the fetus is naturally around 4.5%. The risks in women who have taken therapeutic drugs in pregnancy are just fractionally over this baseline.

Congratulations on your pregnancy and i hope you can speak to a specialist who can discuss your needs. Good luck!

UpsyDaisyDo Sat 04-Dec-10 17:24:26

Thanks so much for your replies. I've done a bit of research and its all a bit ambiguous - like you say ethically its not possible to do the necessary trials to be absolutely sure. I'm going to call the surgery on Monday but am a feeling better about contining taking the meds than I was before. I'm hoping that by my second trimester I'll be so knackered (was super tired all the time when pg with ds1) that I'll be more able to wean myself off them.

I was tossing and turning for hours last night before I relented and took a zopiclone but still only got abouit 6 hours sleep and woke up with a horrific hangover type headache same as yesterday.

thanks again xxx

UpsyDaisyDo Sat 04-Dec-10 17:32:36

Mean't zolpidem! Not adding zopiclone to my list too x

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