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Blood tests show elevated AST liver enzyme in baby DS - does anyone have experience of this?(36 Posts)
My DS had some blood tests, they came back with raised AST, a liver enzyme.
Apparently it could mean liver damage for a number of reasons, or it could come to nothing.
We have to test again in a month. I'm trying hard not to worry. My DS is 7mo and appears healthy.
He only had the blood tests as a precaution because he's large and it's standard for babies over the 99.6 percentile. Everything else came back normal.
Does anyone have any experience of AST / raised liver enzymes?
I'm sorry, I wish I did! It's so long ago, I can't even remember how old he was when it plateaued. I hope all your tests come back negative and your wee one is fine, it's such a scary time xxx
@sunnimama thank you SO much for your response. I really appreciate it. Do you by chance remember what your son's levels were at the plateau? I'm so glad to hear he is doing so well. We are headed to specialist next week so I assume the tests are in our future as well.
Hi @Sarahthompson0630 - I got a notification from this thread in my email! My little boy is now almost five and is completely happy healthy and gorgeous. His levels continued rising for a few more weeks baffling the drs and they were considering biopsies. We did a heap of blood tests and all were normal. The levels eventually plateaued and I decided I had had enough of the blood tests and would pursue a diagnosis if any symptoms showed - he was totally happy and healthy the whole time. None ever did! I hope your little one is the same and everything works out well for you xx
@michellesebastian if you still check this thread I'd really appreciate an update on what happened with your LO. We are facing a very similar situation right now with my 9 week old and I'm a nervous wreck.
@sunnimama I know this thread is old, but if you still check this I'd really appreciate an update on what happened with your situation. We are dealing with a similar situation with my 9 week old and I'm a nervous wreck. Elevated AST and ALT levels but otherwise very healthy and wouldn't know anything was wrong. Thank you so much.
I join this group to share with you our experience with this elevated liver enzymes. I want to say thank you to all the mums especially @Gambrosius who replied here and gave me reassurance that everthing will be fine in nature’s time.
At 1 week old, my baby shows sign of Jaundice and it linger up to 2 months. We did 3 blood test. At the 3rd test @2mos, our pedia advised us to test for liver profile just to be sure that jaundice is not a symptom of something else. We got elevated liver enzymes with AST started at 90U/L. At 10 weeks, it went up again at 140U/L, this was when our pedia refer us to another pediatric gastroenterologist. This was the time I began researching about this liver topic.
The pedia explained to us what we can do is to eliminate possible diseases - we did ultrasound to check liver structure and it was normal, we did a detailed liver function test, hepatitis profile test, hematology (blood profile) test and the only issue is the elevated AST, ALT and biliburin. We test again at 3 mos and its still elevated. The last test that we did @5mos was the TORCH test (to test wide spectrum of infections) which showed some history of the cause — we got positive for IgG CMV — meaning I got an infection when I was pregnant but it was already gone. This test was very expensive but it will only gave little assurance cause there are a lot more unknown infections.
This is the last test that we did that I decided to stop. Even if the doctor advise us to keep checking every month. Cause when i discussed this with the doctor even if we found out the infection, we cannot do anything but to wait until the baby is mature enough to fight it.
i just went back today @16mos just to check if his liver is ok now. And it is fine now. My son was born weighing only 2.5kg. I think his organ was not mature enough during that time. He was also colic so I also suspect that his stomach is also not mature enough to process milk and food. It did get better at 5mos. So as what other moms said, i think some babies have this cause their organs are not mature enough but will get better in time. Cause we have eliminated all important causes that we should detect early like his organ structure is functioning well, he has no hepatitis, he has no blood count issues, and no wide spectrum of infections, It only goes down to what unknown infection did he got. So its better to wait and trust that his little body will grow.
My male baby prolonged jaundice bilirubin total 1.21 ast 128 alt 175 aalkaline 460 baby is active feeding well what to do iam very much worried about this
hi @sunnimama, how's your baby doing? Your description of ferritin and liver enz reading fits my 5 months baby boy exactly! We are going through endless testing (poor baby) but so far nothing is found. Just wanted to know if you have any update on the health of your boy?
Hello all, I hope this thread is still active and I could get an update from any of you as I'm going through the same situation. I have a almost 5 month old premature baby who's lost weight/hasn't been gaining weight in the past month. I'm typing from Rady's children hospital as we speak because she's failure to thrive. She is breastfed and eats a jar of fruit purée a day only and still hasn't gained any weight and she breastfeeds a lot. Her lab work just came back and her liver enzymes are high and the doctors are perplexed as to what might be wrong (why she's not thriving). She's such a happy, easy to take care of baby and she's not lacking in any developmental milestones. Absolutely nothing is out of the ordinary except her not gaining any weight. Her father and I are skinny but I'm short and he's very tall and my baby is really long as well. Wondering what your guy's explanations were
Hi all! I'm glad I found this thread because it has been a very stressful time for me and my family. My daughter who is 7 weeks old has been having elevated liver enzymes as well. At first her pediatrician said that this was common in Asian babies and that he felt that it would go away in time but her levels have continued to rise. Initially her direct bili was 2.1 but it has been rising and the latest is direct bili= 4.2, ALT= 80, Alk phos 530, Total bili 8.3. Her stools are normal color and she's gaining weight. She was born at 7.2 lbs and at her last appt was 10 lbs. If it weren't for her lab work, she appears to be very normal. She just has a hint of being a little jaundiced and we notice a change in her skin tone from time to time. So far she's had an Ultrasound which was negative and then had a HIDA scan which the GI specialist says he does not think she has biliary atresia or neonatal hepatitis. We are still concerned bc he did not 100% r/o BA or hepatitis. He just prescribed her Ursodiol, which she has been taking for a few days and will repeat labs again tomorrow. Hoping and praying the labs will be ok. The GI specialist says that if they are increased then it would be up to us if we want to continue with a liver biopsy or cholangiogram. Anyone else with a baby that they gave Ursodiol to? Any advice or insight will be helpful. We really do hope everything normalizes. The wait and not exactly knowing what is causing the elevated liver enzymes is so agonizing.
I have a one year old who had raised liver enzymes ast and alt since she was first blood tested at 4 weeks. She went on to have endless tests scans done and everything has come back normal. She is due back in to get bloods in the next few weeks to see if the results are now normal I will let you know how we get on. Please God they are normal now.
Hi I know no one has posted here since 2015. But I am going through a similar situation. My lo had physiological jaundice in day 3. And now she is 9 weeks and the jaundice is still there. It is now 7.6. The doctor thinks it's breast milk jaundice but her liver enzymes are elevated. Repeat test in 3 weeks. Wanted to find out what turned out after all these years? The liver enzymes came back to normal? If yes, when?
I've not looked back on this thread for a few months and I'm surprised to find it so active! It looks like this issue with elevated AST/ALT levels are more common than we realize. Our regular paed doctor also mentioned that she has seen an increase in elevated AST/ALT cases this year.
I wanted to post to give an update. My daughter is now 13 months old and her ALT/AST levels are completely normal. All clear!!
We had our visit with her specialist paed gastroenterologist last month when she was 1 and that's when she got the all clear. It has taken her longer than expected to reach the normal levels - her specialist was inclined to feel that this was something that would resolve itself over time (because we had tested for everything under the sun including rare inborn errors of metabolism, and the tests all came back negative) although she mentioned that usually it resolves within 6 months but some might take longer. The diagnosis is neonatal hepatitis - a passing viral infection - although why she had it, how she got it, we haven't a clue. And reading all these recent posts, it seems to be more common than we think.
I wanted to give an update to hopefully give some of you parents some peace of mind. It is a extremely stressful situation to be in, not knowing what it is. The not knowing is particularly hard because you keep wondering is there really something seriously wrong? Or do you trust your gut when you see your child healthy, happy and behaving perfectly normally. Not knowing means not being able to say, ok here's what the issue is, and here's how we can so to solve it, to make it better. There is no action plan to take, no end point to say, ok if we did all these things/ treatment options, etc - we can get to this point where it is better.
The worrying and not knowing and not seeing the signs of abating, of the downward trend despite months and months of repeated blood tests did topple me. And I hope that for those of you who are struggling too, please know that you are not alone. Hold on to hope, and know that you are stronger than you realize.
I'm so incredibly grateful that we can say this chapter is now closed. We got through with hope and faith and prayers, and I'm keeping all of you and your little ones in prayer!
Over the past month, my 3mo old daughter has received several blood tests for liver functions. At first, it was the jaundice that alerted the doctor to order blood tests and ultrasonic, ultrasonic came back good, but the blood test results showed bili level is a little high and AST is 3x higher than referenced highest value, Total Protein is a little low, GGT is about 2x higher. ALT is twice higher.
Today we had the blood tests done again and the ALT and AST is more or less the same level, while the bili is in normal range now. We don't know what the causes are, but last time I presented the test results to the doctor, she asked me if I wanted to give her medicines to protect her level from damaging and for me, it is a no to give my 2mo baby medicine. I don't see any symptoms from my baby, she's beautiful and active, she's perfect. I have no reason to believe anything is wrong with her, besides, the jaundice is gone now.
How do things turn out for your LOs? I'd love to hear from you guys. My wife is very worried because we don't know that exactly is wrong.
My daughter is in the same boat. 9 weeks old...was 7lbs 6ozs at birth, is just back to 7lbs 11ozs now at 9 weeks. Very active, alert, smiley. No signs of jaundice. Not gaining weight so they did bloodwork and found elevated liver enzymes. They are hospitalizing her over night tonight to monitor, and then do an ultrasound tomorrow. Anyone else have any results yet? I know my supply is on the lower end...but they all keep saying it is fine since she has tons of wet diapers daily.
My littlen has had similar to all this at 5 weeks she wasn't gaining much weight after having jaundice I was not bf tho and she was referred to the peads who said they think she's dairy intolerant so changed her milk accordingly and done blood tests and her gamma gt were up, so repeat bloods done and they were going down then all of a sudden around 3-4 months her ALT levels were going up so more bloods done (meanwhile she's suffering with reflux and not gaining much weight) my consultant referred us to a liver specialist hospital and we had a scan and more tests done and the scan come back with fat on the liver so they took loads of blood for metabolic and auto immune disorders and I got a phone call today saying her ALT were over 200 and they are sending her to have a biopsy and a sweat test my LO is nearly 6months and only weighs 11.12 she's little and apart from being a bit grumpy with her reflux and fussy with her food she's normal not as advanced as my other 2 but she's good and happy I found this post and found it interesting has anyone had any answers with similar to my story thank you
My 7 week old has been jaundiced since 1 week, but bili levels did not concern drs. Yesterday blood work confirmed elevated liver enzymes. I have now been advised by her paediatrician to cease bf for 1 week and the enzyme levels will be tested again to see if breast milk jaundice, or my medication (5mg Cipralex) is causing the problem. It is so worrying when there is so little research on new borns and effects of medication, even though I have been advised by my pharmacologist that bf would not be a problem. Would love to hear if anyone ekse is taking Cipralex whilst bf?
hello my grandson is 10 weeks old with elevated liver functions, he was born at 9lb 12oz 23 inches long. He dropped down to under 8lbs and when weighed last night at 10 weeks he is only 9lbs 4oz..... He has elevated levels and does not appear to be thriving. He is breastfed only. He was admitted to children's hospital yesterday...we r concerned....did anyone else have significant weight loss?
So glad I found this thread! My 6 week old also has elevated enzymes, he's been monitored since they were picked up accidently 3 week ago and have been steadily rising. I keep finding info about 'mildly' and 'highly' elevated results but I can't find info on what is high and what is mild! Would be very curious to know others results - my boys are ferritin 1693, total bilirubin 63, direct bilirubin 16, alk phosphatase 510, alt 230, ggt 430, ast 282. He seems completely happy and healthy with no jaundice, but like you all I'm freaked out!
Hannahlatay1210, I'm curious how your LO's situation turns out. We're going through practically the same situation and it's honestly freaking me out a little. I'm waiting for liver enzyme test results as I type this. My LO started out very chunky (9 lbs, 1 oz) and had lost a pound between her 4 and 6 month checkup. We had labs done Friday and had to repeat this morning due to high liver enzymes and high blood acidity. I doubt they would have worried though before weighing her! She is on track developmentally, happy as can be, and eats a ton. She is breastfed too though, so I'm wondering about the connection? She's on solids now and since her last checkup, I added a bottle of formula, but she still isn't gaining weight according to the growth curve. Me and my husband's families are both tiny too though (I'm 5'1", he's 5'10" but his dad is a jockey). I would love for it to be just a plateau in growth and she is just turning out to be smaller than they thought, but these tests are freaking me out.
Sorry it posted before I was done!
....because I do believe maybe I was not producing enough. She's been strictly breastfed till last couple days. Dr loves her energy and her smile and feels she is developing great she is just a little smaller then he'd like but otherwise he has no complaints. However because of the number he is referring us to childerns hospital in Seattle. We live 3 hours away. I am freaking out! To me she is fine and healthy. Never had any odd symptoms. We struggle with acid reflux but that's it! I am so stressed! We will see them in a couple weeks. They are to call to set the appt up. They have not yet. I am happy to read some of the other posts! But I'm still stressing out!
Well some of these post are little old! Hope someone reads and gives me peace of mind!
My daughter will be 4mo the 16th of this month, we recently have seen her pedo, which due to her small size insisted on blood work. My husband and I are pretty small people. As well as his entire family! None of the men are over 5'7 and the woman are all 5' if that and very petite. His sister weighed 18# on her first birthday and 20# he second birthday, but was very healthy! So my LO is a tiny thing. Anyways, her liver enzymes appeared to be elevated. Normal her dr said is 60 hers were 113. She eats good, I am now supplementing beCause
thank you so much for your answer. it means a lot to me to see that you were in the same situation and everything is fine now. I wish you and your little one all the best in the world.
yes, I agree that babies so little shouldn't be tested if they seem ok. I am upset because I gave her phenobarbital at my dr advice for lowering the billi level. And it worked but it is a strong drog and I am positive that it would have been fine over time without takeing it.
Your dr didn't prescribe anything for lowering the billi level?
It is so stresfull with the first baby...
May God give us wisdom to make the right choices.
My daughter's numbers remained elevated until 6 months (when we recently re-tested her again). Her numbers are completely normal now and all she needed was time. She has been the picture of health all along but we still had "specialists" trying to intervene; formula supplement, perform a biopsy, complete an ultrasound, etc.. we did not do the supplementing or biopsy and I'm so glad we didn't! I've spent so much time worrying over this and we incurred many more medical bills on top of delivery costs. While not always the case, often these tests are unnecessary and shouldn't be ordered in the first place. I wonder how many babies (including my own) have had elevated numbers in their early months as their little systems learn to operate properly? Most babies aren't tested outside of the typical bilirubin tests so it's possible many babies have "abnormal elevations" that just naturally resolve over time...
My advice is to trust your own instinct and judgment when observing her every day and to give it more time (unless you're seeing unusual symptoms). Our family found peace and answers through praying and trusting God. It took some time to resolve but we are so grateful that it did! Praying for you and your daughter!
I found this looking for elevated levels for AST and ALT. My doughter is 9 weeks old and we also have breast milk jaundice. Her billi level is 4 and AST/ALT are 83/60. Our doctor said that we can help her liver to "get started to work" and she gave us a syrup LIV52 for a month....
I am positive that everything will be fine because they are so perfect little creatures but theyr bodies are adjusting to this life now...
All the best and please let me know how your analyses are now.
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