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Antenatal tests

Anti E antibodies

4 replies

Monkey29 · 23/11/2014 20:09

Hi, I'm new to this forum. Am 8 weeks pregnant on my second child. Had routine bloods done with my GP and have come back positive for anti E antibodies. My blood group is O Positive. Gp wasn't able to tell me much about it but has said lab recommends that I have blood test repeated at 28weeks and that husband should be tested. Have done a lot of reading on it and from what I gather my husband must carry e antigens and passed them to my daughter and then at some stage during that pregnancy/labour her blood mixed with mine and as a result I developed antibodies to the E antigen. Therefore if husband is tested and it proves he is a carrier there will either be 50%/100% chance that this baby will also have the antigen and then as I have antibodies I will attack it's red blood cells. From what I've read I also gather that I should be have blood titre levels done every 4 weeks at least. I have read the outcomes vary from having a perfectly healthy baby/ a baby that has jaundice in first 24 hrs requiring careful monitoring and treatment/ a severely anaemic baby (haemolytic disease of the new born) to hydrops fatalis which is usually fatal or worst case scenario- stillbirth! Must say my head was in a spin. It has said in several articles though that the bigE antibody usually only leads to a mild to moderate effect on the baby.
So really I'm writing here to see if any of you have experience of this? I want to know is my understanding of it correct so that when I see my consultant I'm able to ask the right questions or insist on the correct treatment if needed. I would be so grateful for any feedback or if any of you have had these antibodies on a previous pregnancy what was the outcome. I know there's nothing that can be done apart from careful monitoring but ild like to be fully prepared for whatever eventuality. Hopefully I am worrying for nothing!

OP posts:
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Hopetobeamumof4 · 02/02/2022 19:39

I know this is super old but what was the outcome of your issue? I have anti e antibodies and I’m 15 weeks and so scared x

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Internetio · 02/02/2022 19:45

I had little e and big C antibodies. We were watched closely for signs of her becoming anaemic and I had weekly blood flow scans from 28 weeks I think- the upshot was that she was induced at 34 weeks and spent 2 weeks with quite bad jaundice but is otherwise absolutely fine 😁

Good luck and don’t panic!

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Hopetobeamumof4 · 13/02/2022 09:48

Thank you so much for your reply x

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Gingerandbiscuit · 13/02/2022 09:54

Hello, I had anti-c antibodies. I just had to have regular blood tests to monitor antibody levels throughout the pregnancy. My baby was absolutely fine. A little jaundiced but not enough to require any medical intervention.

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