Fine to me. However I didn't get the connection between Luke and Leia who we used to live near, ntil DH pointed it out, nor could I understand why my Mum and Dad laughed at my friends baby George Harrison.
Rose Tyler is a lovely name and I wouldn't let the Dr Who connection put you off. Whatever name you choose could become the next huge thing in books or films anyway. There must be dozens of Harry Potters who had the name long before the books were written!
No problem at all with Rose for your DD and Tyler for your DS. The only people who will notice anything are Dr Who fans and they will just think it's cool! Plus as Trillian said you would usually introduce them separately or with the oldest (Tyler) first anyway. My DD's middle name is Romana - DP is a HUGE Dr Who fan!!