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Nuchal results on mums over 35

(84 Posts)
gunwalloe Fri 07-Mar-14 18:35:44

Ive decided due to my age to have the harmony test 10 weeks at incase my nuchal comes back high risk but am interested to hear if many mums over 35 have had really low risk scores back?

Also interested in high risk to for balance.

Cariad007 Fri 07-Mar-14 18:47:02

Mine was 1 in 190 which was classed as low risk but slightly higher than the average for my age (37). My son is fine though.

squizita Fri 07-Mar-14 18:53:34

In my area most births are to mums of 35+ (due to property prices etc' people only start families 30+) and amongst my 35+ peers people don't go for Harmony unless they get a high risk result as an alternative to invasive tests. I am planning the same (currently waiting for results). I notice friends from other areas where older mums are rarer tend to be cautious.

I believe the average for 35-40 is still 1/350 so way under even 1% chance.

gunwalloe Fri 07-Mar-14 18:58:08

cariad007 did you have any extra tests?
squizita im a real worrier so wanted to be sure the baby was ok as soon as I could, good luck with your results

DitaVonCreamTeas Fri 07-Mar-14 19:03:02

1 in 2500 aged 39. Hope your results are ok. smile

ChazzerChaser Fri 07-Mar-14 19:05:34

I got something like 1 in 35000. It was so low risk I rang to check as I didn't know it went that low. I was 34 when pregnant by a whisker, so 35 when had test.

screamingeels Fri 07-Mar-14 19:14:33

I had nuchal fold tests at 38 and 41, they both came back really low; in the 1000s, can't remember exactly what now. But I know for the second I walked in with a 1 in 95 chance on age alone and walked out with almost lowest chance possible.

SharpLily Fri 07-Mar-14 19:15:01

38 and 1/1757, which I was pretty happy with but the Harmony test wasn't available to me here. I think I would have gone for it if it had been.

SandwichBag Fri 07-Mar-14 19:17:01

I've just had mine and combined test came back 1 in 9300 (I'm 35)

Missmidden Fri 07-Mar-14 19:19:27

I had 1 in 21000 at 37. Remember it's combined not just on the nuchal thickness. That was 2.3mm for me (though I was 13+4 at scan) so I thought the risk would come back higher than this. DP and I had already decided what our threshold would be for further tests so the combined result came as a lovely surprise.

Expectingtwins1975 Fri 07-Mar-14 19:29:09

38 and 1:2400 .... Had harmony test done as part of a free nhs trial and it was 1:10000

stargirl1701 Fri 07-Mar-14 19:31:53

DD at 35, pg with DC2 at 37. Both low risk after nuchal combined test.

eurochick Fri 07-Mar-14 19:44:15

I also had the Harmony. My age related risk for Down's syndrome was 1/130. My combined result came back at 1/2600, so pretty reassuring (and the Harmony came back at 1/10000). I'm 38, btw.

hubbahubster Fri 07-Mar-14 19:54:30

I'm 37 and my adjusted risk of trisomy 21 is 1:5711, 18 is 1:67396 and 13 is 1:158655. That figure for Downs is considered low risk. Baby's shown no markers for Downs at either scan so far so I didn't consider further testing.

This baby's nuchal measurement was lower than DC1's and he's fine so I haven't been concerned.

bassingtonffrench Fri 07-Mar-14 19:58:19

At 38 it was 1 / 940

Cariad007 Fri 07-Mar-14 20:01:29

gunwallow my bHCG level was three times the average. That was what was skewering my result. I didn't have any extra tests but I did have a very thorough anomaly scan with a fetal medicine consultant who didn't find any problems or further markers for Downs. Had I been 25 and got the same result then I would've pushed for more testing as 1 in 190 would be way beyond the average for my age but as it was only just higher than average for 37 I left it. The NT measurement was only 1.5mm, nasal bone was very visible and all my other blood results were fine, so I guess I just have a naturally higher bHCG level.

Not sure if you are in London but I think the Harmony test is available on the NHS at King's College hospital.

Tomkat79 Fri 07-Mar-14 20:01:59

At almost 35 I got 1:100000, had to check and recheck but was right. Then my midwife pointed out I could always be 'the 1'. Yes thanks for that!

Emberlina76 Fri 07-Mar-14 20:17:41

I'm 37 and mine was 1:59. I had the Harmony x

Miriama Fri 07-Mar-14 20:20:54

I'm 38 and mine came back at low risk 1:2400. Hope your results are good!

Waiting for my harmony results as my combined risk is 1/37 sad

I'm 34.

I would recommend getting it done at 10 weeks if you can to avoid the worry of a high risk result at your 12 week screening and the awful 2 week wait afterwards...

Lucky3878 Fri 07-Mar-14 20:30:46

I'm 35 and my nuchal fold measurement was 6.88, blood results low risk. Advised to have CVS. Based on measurement alone I was told 60% chance of some type of chromosome disorder and unfortunately we didn't get good news. Hoping my post doesn't upset you, I know you asked for low and high results. This time round it didn't work out for us but that is certainly not the case for everyone and some ladies even with a high measurement have no abnormalities detected and go on to deliver a healthy baby. Not giving up with increasing our family though and wishing you lots of luck and good health

Sorry Lucky sad

Good luck for the future.....

gunwalloe Fri 07-Mar-14 20:37:19

Thanks for all your responses I am probably being over cautious getting the harmony at 10 weeks but being a anxious person for my own peace of mind its worth it. Its great to see all the over 35s getting low risk smile

cariad im having my harmony done at the FMC in London

lucky3878 sorry it didn't work out for you last time I hope you have good news next time

haveyoutried good luck with your results how long do you have to wait for your results?

Lucky3878 Fri 07-Mar-14 20:39:41

Thank you. We will definitely be looking into getting the Harmony test when I fall pregnant again although genetics team don't consider me to be high risk of having the same problem. Fingers crossed though wink

Early next week Gun - though when I was in the hospital this week the midwife said it would definitely be by today so I got all psyched up and am now fed up!

Some people of course decline the screening altogether. It never occurred to me to decline any screening as I didn't think through the worry or decision making it might involve.

nyldn Fri 07-Mar-14 21:15:28

haveyoutried, I'm 34 and was 1:37 as well. had the harmony test offered through the nhs and got the 1:10,000 low risk. good luck w your results

Thanks!

WipsGlitter Fri 07-Mar-14 21:19:51

I declined all screening. I think if you're a "need to know" person then just get the amino.

BikeRunSki Fri 07-Mar-14 21:24:18

At 37 I was 1:4000 with ds
At 40 I was < 1:10000 with dd

I have been reading your other thread OP. Good luck with your Harmony test.

Fasterkillpussycat Fri 07-Mar-14 21:29:30

At 38, mine was 1 in 100,000. We had already had the harmony test when the nhs results came back - 1 in 10,000.

Good luck with your tests.

dats Fri 07-Mar-14 21:30:49

I'm 41 and 33+3.

Had nuchal measured and bloods done at 12+3.

Nuchal fold was 1.73
Risks after bloods were calculated at 1:1668 (background risk assumed to be 1:89) for Downs. Edwards & Patau both considerably lower.

I think we'd decided we'd do Harmony if risk came back greater than 1:200.

TheFabulousIdiot Fri 07-Mar-14 21:31:25

Mine was one in 70 I think, but I was 40. I had the manikin the end.

adaloveslace Fri 07-Mar-14 21:58:11

I'm 38. My results from the combined screening were 1:25. I had a cvs and results came back clear but if you're a worrier (like me), I would advise doing the Harmony. The wait for cvs results was just awful.

Foxeym Fri 07-Mar-14 22:06:09

Mine was 1 in 19000 and I'm 42, DS is now 20 weeks

LadyGoneGaga Fri 07-Mar-14 22:06:54

I'm 35. Nuchal results came back 1 in 95, high enough for them to call me in and offer a CVS (this was due to extremely high HCG and low pappA hormones, the actual nuchal fold measurement was fine at 1.5). I went for Harmony test at the FMC rather than an invasive test. That came back 1 in 10000.

Also worth noting that the repeat nuchal done at the FMC used many more soft markers than the NHS nuchal scan and so their calculated risk came back as a much more reassuring 1 in 330. Still went for Harmony though as needed to know.

Plateofcrumbs Sat 08-Mar-14 06:20:24

If you're having a Harmony test be aware there are only two results - positive or 'negative' (1:10000) - the 1:10000 is calculated as the general risk of Harmony giving a false negative, it's not based on individual risk assessment.

Heatherbell1978 Sat 08-Mar-14 08:30:06

I'm 36 and mine was 1:2050

lucidlady Sat 08-Mar-14 08:51:16

I'm 37 and Nhs result was 1 in 6,800. Harmony came back 1 in 10,000. NT measurement was 1.1.

Lagoonablue Sat 08-Mar-14 08:57:26

At 46 my combined test was 1 in 250. Pretty good for my age and 'low risk'.

grizzabellia Sat 08-Mar-14 09:06:33

1 in 3500. Was 36 at time, 37 now (baby due soon). For my first child aged 31 was 1 in 28000, 2nd age 33 1 in 50000 (consultant asked if I was getting younger!) Was a bit worried this time that result was (although still low) not as good but when I said to midwife she pointed out I was older and this is part of calculation!

RiverTam Sat 08-Mar-14 09:09:09

I was 38 and mine was something like 1:4,500.

livingzuid Sat 08-Mar-14 09:26:16

1:2190 after my NT scan. I'm 35.

EssexGirlLottie Sat 08-Mar-14 09:46:22

Hi there. I decided the same thing OP. I'd never heard of the harmony test but I then heard about it from a friend who had it after a high risk nuchal fold. I decided, being pg at 36 , I didn't want to wait until after nuchal scan so had harmony at 10 weeks and then NHS nuchal fold at 12 weeks.
Got the harmony result back first: 1 in 10000 :-)
Interestingly, my nuchal fold combined test then came back at 1 in 100000!
So maybe I needn't have bothered with harmony but it was nice to have an early scan.
Good luck

Booboostoo Sat 08-Mar-14 10:18:36

Mine was 1:1600 at 38, I'm having my second one on Monday at 40.

Did I understand correctly that you want to do the Harmony and then the nuchal? If yes, you may want to discuss this with your doctor as I don't think it makes much sense.

The issue with the nuchal is that it has a 5% false positive rate which then leads women to have an amnio which has a 1% change of a miscarriage. Combine the two statistics and it means that some of the miscarried foetuses after an amnio will have been healthy.

The Harmony test has a lower false positive test (3% I think) so less chance of sending women with a healthy pregnancy to an amnio. So if you have a negative Harmony you wouldn't have an amnio anyway (false negatives are equally low for Harmony and nuchal), if you have a positive you need to consider an amnio.

WhipsGlitter that is indeed your choice, but the reason women try to avoid the amnio even when they do want to know is because of the miscarriage risk. The Harmony test and the nuchal scan do not have a risk of MC.

gunwalloe Sat 08-Mar-14 10:32:17

booboostoo im having the early package at the FMC you have the harmony test at 10 weeks then go back for the results and nuchal at 12 weeks. Im a real panicker and couldn't stand having a possible high risk nuchal and then having to wait two weeks for a harmony result so im doing it this way round instead. I may be jumping the gun but for me its worth it.
Good luck for yours on Monday

Booboostoo Sat 08-Mar-14 11:13:33

Thank you and good luck as well! Unfortunately the Harmony is not available here (rural France!) otherwise I would have chosen it over the nuchal.

JBrd Sat 08-Mar-14 11:19:04

I had 1:4500 with DS at age 39.

I'm now 42 and pg with DC2 and will be doing the Harmony test before I even had the nuchal scan (cheaper that way).

gunwalloe Tue 25-Mar-14 15:43:22

I can add my result now 1 in 5095 which im really pleased with I was convinced I would be high risk. Just waiting for the results of my second harmony test as the first failed but im not panicking now like I was before.

thebestnameshavegone Tue 25-Mar-14 16:41:11

currently 21 weeks pregnant, risk was 1 in 3500 aged 36.

sleepyhead Tue 25-Mar-14 16:43:26

Mine was 1:23 at 40 (baby was fine). It was 1:20000 at 34.

Was bloods that drove up my score in the first instance though. My nuchal measurement was very small.

eurochick Tue 25-Mar-14 16:59:04

I did the same as you - Harmony at 10 weeks, and nuchal + Harmony result at 12 weeks, at the FMC. I'm glad you got a good result from your nuchal.

SicknSpan Tue 25-Mar-14 17:00:14

Nuchal measurement was 2.3mm and risk came back as 1:14000. I am 38 and my two previous babies had result of 1:250 (at age 29) and 1:3500 (at age 33) so I was surprised.

Good luck with your pregnancy.

I'm 35. Nuchal was 2.1

Risk came back 1:3000

Good luck OP. I would still have had the Harmony for peace of mind if it wasn't so bloody expensive!

BakingBunty Tue 25-Mar-14 18:06:31

I had a risk of 1:27000 with DS when I was 35.

And 1:46000 with this pregnancy at 37. I was surprised it was lower second time around.

I think the Harmony test is amazing and would definitely have had it done if results had been higher risk. But would have declined amnio or CVS unless the risk was well under 1:100.

I really, really hope that Harmony becomes standard in the NHS - seems so unfair that finances dictate who can and can't access it. But I guess it's always a matter of prioritising in the NHS.

quickdowntonson Tue 25-Mar-14 19:01:06

My nuchal fold was 1.3mm
My harmony test results were low risk (less than 1:10,000).
I'm 42. :D

squizita Tue 25-Mar-14 19:30:20

I'm 35. My result was 1/100,000! Apparently they gave me this because they cannot give anything more.

Mintymoomoo Tue 25-Mar-14 21:03:03

Just had my combined results back and got 1 in 34000, I'm 34 will be 35 month after baby arrives!

Was talking about this with some friends other day, they all commented on my results they all had 1/1500 in there 20's in there pregnancies

MarthasHarbour Tue 25-Mar-14 21:53:25

I got 1:7700 at age 41

ChicaMomma Wed 26-Mar-14 17:43:58

i'm 37, mine came back as 1:64,000.

We had discussed it and decided that if it was >1:150 then we'd go for the CVS. I plan on having a second baby, and obviously i'll be closer to 40 when (and if!) that happens, so we have already decided to go straight for the harmony that time. It's a couple of 100 more expensive but i think given my impending advanced age by then, it would make more sense.

time2deal Thu 27-Mar-14 15:46:12

I'm 37 and got 1:2900 from nuchal and bloods, and 1:100,000 from Harmony. (Could be 1:10,000... the lowest they give).

By the way he said the age related risk is 1:140 at 37 based only on age. I was terrified to get this result actually so very pleased. Nuchal was 2.1.

Rubyshoe Thu 27-Mar-14 16:46:52

Results came back today and was happy but shocked to see a risk of 1:40,731 Nuchal fold was 1.5mm so had been hopeful. Am 37, will be 38 in couple of months. For various reasons my midwife actually tried to put me off having the test but am glad I did now as hopefully it's one less worry x

Booboostoo Thu 27-Mar-14 17:52:32

My results just came in, 1:520. The doctor said she was happy with this as my NF was 1.6mm and my bloods good but just my age (41) that pushed the risk up. No Harmony test available here otherwise I would have liked to have done it.

Harmony is not the standard test yet as it is a very recent test and NICE are waiting for enough confirmed correct results from pregnancies coming to term. I remember in 2010/11 when I was pg with DC1 the first small scale study of it had just been published, so it's early days yet in terms of large scale data and it makes sense for a public policy making body to be cautious about something as important as this.

weebigmamma Thu 27-Mar-14 17:54:26

I had odds of 1/35 at age 38. Harmony test came back clear. So expensive but totally worth it for peace of mind.

Racal7 Fri 28-Mar-14 08:13:02

1 in 64,000 at 35

ViXter11 Sun 20-Apr-14 21:20:40

Hi I am 41 and 18 weeks pregnant. No amnio. Nuchal fold plus tests gave me 1:9500 and Harmony negative for all trisomy. All the best to you all

livingzuid Mon 21-Apr-14 07:18:36

I'm 35 and three quarters smile NT result was 1:2199 after bloodwork. They don't tell you the scan result here (Netherlands) but I was staring at the screen and it was around 2.4mm but that was at 13+4 so right at the time limit of the test.
On age alone I was 1:290 which freaked me out.

If the result had been in the 100s I would have travelled to Brussels for the NIFTY which is similar to Harmony and paid. Not available here yet although it will be soon.

Good luck tbusmile

SofiaAmes Mon 21-Apr-14 07:27:25

I had very low risk nuchal fold when pregnant at 39, but decided that I didn't trust the results (and the limited issues that nuchal tests for and the efficacy of the test) and had an amnio in the end (which came out fine).

JBrd Mon 21-Apr-14 07:44:47

With DS at 39, my combined risk was 1:4500.
Now pg with DC2 at 42, combined risk came back at 1:17 confused Nuchal fold 1.1mm, but my Papp-A is very low.
Harmony test failed twice, so am now going to have amnio.

OneLittleToddleTerror Mon 21-Apr-14 07:46:09

I was 35 for my first and now 39 pregnant with my second. Both times the combined tests for downs came back with 1 in 2000ish. I think this is pretty good for my age. Don't worry too much. Lots of older mums around with ok results.

Pregnantagain7 Mon 21-Apr-14 07:46:32

I'm 36 measurement was 1.6 and the result after bloods was 1:39000 so very low obviously I was very relieved but wasn't expecting it to be so low.

curiousuze Mon 21-Apr-14 07:48:25

I had a nuchal fold test which came back at 6.5mm - very very high, so it was a case of finding out what was wrong rather than wondering if something was definitely wrong. I then had a cvs to confirm there was a problem. I was 35. I had a problem free pregnancy the following year though.

OneLittleToddleTerror Mon 21-Apr-14 07:50:04

I have also decided before hand that if I got 1 in 250 or worse I would go for a harmony test. I think it is just how comfortable with the risk factor.

beeny Mon 21-Apr-14 07:52:09

I was 35 and test was 1:38,000

drivenfromdistraction Mon 21-Apr-14 08:00:55

Age 40 I had 1:5,000 with DC3 - because of her large nose bone apparently! (She had a perfectly ordinary size nose at birth)

KatharineClover Mon 21-Apr-14 08:57:37

I'm 35 and my NHS result was 1:73000. For my DS (when I was 31) it was 1:15000 so I am surprised it is a lot lower this time.

Foxeym Mon 21-Apr-14 09:24:42

I'm 42 and my results came back as 1:19000 which I was really surprised at. I didn't have the test with my other 2DCs as I was in my twenties then

LightTripper Mon 21-Apr-14 11:42:43

I am 38 and had Panorama (v similar to Harmony) for same reason as you. I didn't have the hormone tests done as Panorama had already come back clear, but nuchal fold was tiny (less than 1mm I think) so I think my combined test results would have been OK. But it did mean I could look forward to the scan rather than worrying about it.

Still worth having the scan IMO as they are not just looking for genetic abnormailites, here are other problems they can check for. Plus it was really nice to see her again!

Fissawissa Mon 21-Apr-14 19:14:46

I'm 34 & the nuchsl scan was 1.40mm and the adjusted risk of Trisomy 21 is 1:209. My letter said low risk but now I'm seeing the results in their thousands & I'm a bit worried.
Am I reading my results wrong?

MrsPatMustard Mon 21-Apr-14 21:28:27

Was 39 and the result came back as 1-30,000. Much better than I was expecting. Now have lovely little boy grin

gunwalloe Mon 21-Apr-14 22:30:48

fissawissa anything over 1 in 150 is considered low risk. If your not happy with the result you have you could have the harmony or nifty test they aren't cheap but if you want piece of mind it may help you.

honeyharris Tue 22-Apr-14 14:19:17

My NT score was 1:4600 (I'll be 38 when baby is here) and I also had the Harmony test at 14 weeks as didn't feel sufficiently reassured by the score (however I am very anxious and have a cousin with Downs so it was on my mind from the beginning). I would have opted for amnio but husband wasn't keen so thought Harmony was a happy medium.

Jo178 Tue 22-Apr-14 14:22:26

Mine was 1 in 16,000 at 37.

JustGotMyBabyOnBoardBadge Tue 22-Apr-14 15:22:26

I'm 35 and my combined result came back today of 13,000:1 which I'm grateful for - however I could always be the '1' [hmmm]

Reckon I could just be a bit negative as can't find anything I want to eat without making me want to hurl...

splendide Tue 22-Apr-14 15:23:55

Just got mine. Letter said 1:15,000 but when I read the actual notes it was 1:1,500. I presume the notes are right and the letter wrong. This is a little higher than I was hoping for but I think either counts as low risk. I'm 34 now but 35 at EDD.

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