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acyclovir during pregnancy?

(20 Posts)
walnut300 Sun 06-Jan-13 12:05:21

I was wondering if anybody has taken acyclovir 400mg tablets throughout pregnancy. I am 6 weeks pregnant and stopped taking the tablets as soon as I found out I was pregnant and now have an out break, wondering if it is safe to take? I am new to mumsnet and have heard this is a good forum for advice. thank
you smile smile

PetiteRaleuse Sun 06-Jan-13 12:06:25

AFAIK it's ok, though check with your doctor.

DreamingOfTheMaldives Mon 07-Jan-13 11:27:58

I spoke to a specialist doctor about this only last week as I had taken 3 days worth before finding out I was pregnant. I was told not to worry, there are no known risks associated with acyclovir (a book of medications he looked in gives it exactly the same result as paracetamol, basically not believed to cause problems, but obviously can't say it is completely safe as no one does studies on pregnant women.) I also found a report (may have been an American one) which said there were no increased defects between women who had taken acyclovir in early pregnancy and those who had not - the rate of defects remaining at 2%.

He gave me 3 packs of the medications to take as and when I get outbreaks as I have been getting them quite frequently this year. (I find that taking it shortens the outbreak and reduces the severity of it). He told me that he would personally avoid taken them in the first trimester, but to not to worry that I had already taken some early on, but that it really was a matter for me either way. It was not known to increase risks at any stage and therefore if I chose to take in tri 1, that was fine. He said I could take them freely when I got outbreaks (as I would undoubtedly do due to weakened immune system from pregnancy) during tri 2 and tri 3 if that is what I wanted to do - he understands that some women try to avoid taking any medication at all during pregnancy if they can avoid it but it is very much personal choice.

He strongly recommended taking suppression dose from at least 36 weeks onward in order to avoid the potential for a CS if I had an outbreak at the time of going into labour. He said that if I wanted to, I could take it for suppression throughout my pregnancy but I prefer to take it as and when I get an outbreak.

Poppetwagon Mon 07-Jan-13 13:21:15

Congrats ladies smile I'm in pretty much the same boat. Just found out I'm about 4 wks pg this morning, and have taken acyclovir suppression 2x a day for years. I don't get many outbreaks and when I do they are quite mild, but i think, like Dreamingofthemaldives, (thx for info btw!) I will only take them when i feel an outbreak coming on. I've also heard it is quite safe to take while pregnant.

walnut300 Mon 07-Jan-13 13:58:03

thank you so much for the advice. I also have been taking it as a suppression for years but as soon as I found out I was pregnant have stopped taking it and then got an outbreak. I am going to try and hold off from taking it but am concerned about having an outbreak nearer the time of birth. so it is adviced to take it at 36weeks? what mg do you usually take? I live in Thailand so really value this advice from you. thank yousmile

DreamingOfTheMaldives Mon 07-Jan-13 15:53:55

I take 5 x 200mg per day for 5 days for an outbreak. It's so many because you are trying to overload your system with it so that it can fight it. Start taking it as soon as you notice a tingle/sensation. I've only recently started taking it and have been amazed how well it reduces the severity of the attack - I only get an attack in a very very small area but the last couple of days it is incredibly painful (due to the position) and make me so miserable. Taking aciclovir means it doesn't get to that stage. Yipee!!

I've had it for years but was never actually diagnosed properly until October, so didn't take aciclovir, as their ability to diagnose it wasn't as good years ago - I just got on with it and never bothered going back to the doc. Glad I decided to in October (probably because I was feeling so miserable after just having a miscarriage and then an infection and then getting an outbreak just felt like kicking me when I was down!)

I was told that they would recommend taking 3 per day for suppression (I assume at 200mg each) during those last few weeks as they want to make sure that it keeps it away. I will be going back to see the doctor before then though so can talk to him about it.

Have either of you noticed any side effects from taking it as suppression for so long? I had been a bit reluctant to take tablets for suppression (generally, I don't mean whilst pregnant) but I'm not really sure why.

It's good to be able to 'talk' to someone who understands as I've never spoken to anyone other than my husband about the outbreaks etc.

Congratulations by the way ladies smile

ZuleikaD Mon 07-Jan-13 16:32:40

It's fine to take. I've been told to take it throughout my third trimester as you really, really don't want an outbreak when the baby's born.

Poppetwagon Mon 07-Jan-13 17:33:31

Myself, I've never had any side-effects from taking suppression acyclovir. Not a single one. And it works great. So naturally I'm a bit nervous stopping until 3d trimester but I'm sure it'll be ok.

walnut300 Tue 08-Jan-13 11:13:33

hey ladies, congratulations to you! grin I have taken 400mg 2 x a day for over 3 years now and never had any side effects, I am much happier taking it as a suppressive dose as i nevet get an outbreak. I will consult with my doctor as going to continue to not take it now as so early in to pregnancy but will look at taking it again in trimester 3 as I would much prefer a natural birth than a CS but don't want to place any risk to the baby. feel so much happier being able to talk with other expecting mums, smile

walnut300 Tue 08-Jan-13 11:14:36

zuleikaD what dosage have you been told to take during your 3rd trimester?

ZuleikaD Tue 08-Jan-13 12:26:59

The normal prophylactic dose - 400mg twice a day. It's a bonus that it's free at the moment!

DreamingOfTheMaldives Tue 08-Jan-13 14:48:56

Do you not get it free anyway ZuleikaD? I've been given it free each time, although I don't get it from GP.

ZuleikaD Tue 08-Jan-13 16:10:33

No - I just get a repeat prescription from the GP (I don't use it all the time) so pay normal prescription charges.

dizzyange Wed 23-Jan-13 10:02:05

Please could somebody help me. I have had lots of IVF treatment but I also suffer with herpes outbreaks. Because at my last IVF I had a massive outbreak just around implantation time I was put on suppression this time and took acyclovir for the first 3 weeks. I got pregnant but miscarried at 7 weeks 3 days and now keep thinking it must have been the acyclovir that caused this. Can anyone help/give any advice/or have any knowledge of this? Really really torturing myself over this one.

Goldstar185 Wed 11-Jun-14 09:43:19

Hello
I don't know if this has already been answered but I'm finding it difficult to find out how much aclyvior to take during my out brake at 39weeks? My midwife and doctors are really hard to get hold of! Does anyone know?
Thanks smile

Beardy123 Wed 07-Jan-15 00:23:29

Hi everyone
Am really struggling at the moment.... Just found out I'm 8 weeks pregnant. In the last 3 months I have had 2 x flare ups and woke up this morning with my 2 x massive bout of painful shingles on my leg! I already have a 2 yr old so am constantly paranoid about bedding and baths and towels ect. Not only feeling ill and tired and run down which makes it worse. Also this will be the 4th lot of acyclovir I have had since being pregnant sad which I'm worried about, saw the doc today and he said no proven effects of taking when pregnant but it can't be good in such qty surely?! I also asked if ok for me to take it constantly to stop outbreaks but he said that's no point as dosent work like that. Do I get a second opinion? I don't want to be ill all the time sad

Bubba19alicia Mon 12-Jan-15 09:05:44

Hey beardy123, I have suffered with herpes for 2 years. My sexual health clinic says that more than 6 outbreaks a year is classes a severe, and I was getting at least 1 a month! Normally a dr would suggest suppression, which involves two tablets a day for 9 months, hoping that your body will build up an immunity to the virus. I never did build up this immunity so my local GUM clinic prescribes me 3 months at a time, and I take them constantly and never suffer with an outbreak, unless I miss a tablet. I am not sure how safe antivirals are during pregnancy, I'm nearly 7 weeks an on aciclover, my dr said I should cut down the dose but my GUM said its perfectly safe... I do however know that an outbreak during the first trimester is dangerous, and also near the time your going to give birth. You have to weigh up the risks and benefits of the tablets compared to the risk of an outbreak, and for that reason I am continuing my suppression throughout pregnancy. Would deffo get a second opinion though!!! Hope this helps smile

luckiestgirlintheworld Mon 12-Jan-15 10:43:18

I was prescribed a suppression dose for the last few weeks of pregnancy, so I would assume its fine?

Letmeeatcakecakecake Mon 12-Jan-15 10:48:59

It's fine! You can take your normal dose, or cut down to a suppression dose 2 a day).

Generally if it's not your first outbreak they're not too concerned about outbreaks and vaginal births as the risk if transmitting to baby are very low!

I'm going to take a suppression dose from 35 weeks though, my fanny rill be sore enough after delivery! Last thing I need on too is an outbreak! Xx

kendrickreaves Fri 19-Aug-16 12:13:53

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