secondary recurrent mc's - can immune problems be a problem if you have already had one child?

(6 Posts)
Lucinda15 Thu 26-May-16 08:13:37

I had one DS in an unplanned, happy and smooth pregnancy 5 years ago. Started TTC #2 last year and have had 3 mc's (11.5 wks, 5wks, 8wks).

I have been referred to 3 mc clinics all offering slightly different things; my local rmc (routine mc screening), st Mary's London (sticky blood etc) and Coventry (immune testing).

St Mary's explained that even though I have had one successful pregnancy, the sticky blood could have developed over time.

I'm due to see Coventry next week - but started wondering if immune problems would have been there all the time, and if my first pregnancy indicates this is not a problem for us? They didn't ask over the phone when I called them and I'm only thinking of it now.

Has anyone had experience of either sticky blood or immune problems being the cause of recurrent miscarriage after a successful pregnancy? Interested to hear of other experiences.

Tia xx

JOMH1982 Fri 27-May-16 08:31:48

Hi,

I'm afraid I haven't got any answers for you,but I'm in the same boat as you. We've got a four year old and have lost three babies in last three years, two early and one late miscarriage. I'm getting my NK test results back from Care today so hopefully will get some answers. Seeing st. Mary's for my follow up on 12th July. Feeling quite despondent about it all tbh, pretty much all my friends have had their second baby while we've been trying, and some people have had both of theirs in this time as well. That's interesting that st Mary's said sticky blood can develop over time.

I'll update about NK results later if you'd beinterested. Hopefully we will have our happy endings soon.

Jess x

JOMH1982 Mon 30-May-16 21:06:53

Doh, just realised that I hadn't read who'd posted this before I responded the other day, and of course we've been chatting on another thread! Serious blonde moment, lol. Hope you're ok and that it appt at Coventry goes well xx

peripateticparents Mon 30-May-16 21:19:57

My first pregnancy at st Mary's rmc wasn't sticky blood (live birth). My 2nd pregnancy tested as sticky blood and I was treated as such (mmc but chromosomal). So it does seem to change. I had immune treatment too for the following two pregnancies but that was private and hadn't been tested before. 2nd was a live birth. Best of luck

BlueGazebo Fri 03-Jun-16 09:37:27

Hi
I had one normal, healthy pregnancy followed by 5 losses (18wks, 15wks, 12wks, 11wks and twin at 7wks). I tested positive for lupus anticoagulant/Hughes Syndrome. I had another loss on the treatment but tests were carried out which showed the baby had a chromosome disorder so would have miscarried anyway. Losing one twin early on could also have meant that the second twin was doomed. So, there could also be different reasons for some of your losses. I finally went on to have a second DS taking aspirin, heparin and progesterone. I also developed pre-eclampsia with this pregnancy and was induced at 37 weeks. I went to a high risk pg unit and had almost weekly scans and blood checks. Although I had tested positive for auto-immune issues, I do seem to remember tests also coming back negative so perhaps it is something that can fluctuate. This is 10 years ago now. I remember there being discussion about whether or not you should start taking the aspirin before or after conception - something to ask about. I seem to remember St Mary's advised against taking it beforehand whereas other places advised to take it before. Things may have moved on from when I was in the thick of it all. Dark days. Good luck to you - I always used to tell myself that I had done it once and so could do it again.

Miloarmadillo1 Wed 08-Jun-16 22:41:01

Yes. I had DS1, MC, DS2 ( no treatment but dodgy pregnancy, lots of bleeding etc) then 3 more MC. Diagnosed at Coventry with uNK cells of 16% ( normal is <5) and had a successful pregnancy on treatment. Prof Q said that's a common pattern, that something in an earlier pregnancy 'triggers' the immune dysfunction and it gets worse with subsequent pregnancies.
Good luck!

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