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Miscarriage/pregnancy loss

Has any one had this treatement and was it succesful for you?

14 replies

cherrychoo · 19/02/2011 17:47

I have numerous problems,
been ttc for 14 months since my 5th mc

Went and had loads of bloods taken.

All have come back normal.

Treatement recommended is:

When/if i next get pregnant to have
5g folic acid,
Daily asprin
Luetenising hormone injections twice a week till week 12.

Give it another 6 months of ttc then go back & begin to worry about fertility.

( I have a 7 year old but had 2 mcs prior to having him)
During last miscarriage i asked them to check my overies during an internal scan...normal.
I am 40btw

Any one had this and did it work?

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Notnowcato · 19/02/2011 23:00

Sorry, I can't help from personal experience. But someone I know had one child after nine miscarriages (over seven years). At the age of 42, after another three miscarriages, she gave up trying for her second child. I think now she feels that she wished she had kept on trying. She also feels that she wasn't taken seriously enough, early enough. I obviously don't know the details of your experience but I would say that you often get more 'attention' from doctors if you are more demanding ? so I would say that, at 40, going away and trying for another 6 months is a pretty disheartening prospect?

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hairylights · 19/02/2011 23:01

Hi . I have had the prescription of aspirin for next time but not the progesterone injections. I am waiting for my tests after 3 miscarriages.

I've heard lots about It working for others.

Didn't want to post and run

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hairylights · 19/02/2011 23:04

Ps I'm 42. I don't have any time to waste either.

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Iggi2011 · 19/02/2011 23:49

Cherrychoo do you know what the folic acid is supposed to do? (I'm assuming that's a high dose at 5g?)
I feel your frustration, it is a (very) long time to wait. Sad

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cherrychoo · 20/02/2011 21:09

I questioned whether the folic acid 5mg was to prevent nueral tube defects on account of my advance age thus increased riskand the Doc said that actually it is to enrich and provide nutrition to the uterine wall.

Was wondering if anyone tonight has had this treatment and if it worked?
thanks

chezza x

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FrozenNorthPole · 20/02/2011 21:19

After 3 losses I have had two successful pregnancies on a regimen of progesterone pessaries, 5mg folic acid (it was my impression that it's useful in the case of MFTHR issues, which are clotting problems that quite a lot of UK docs don't test for) and low dose aspirin. For DD1 I also took prednisolone 5mg per day throughout and had HCG injections for first 14 weeks (assume for v similar purpose as the LH injections you mention, since they are almost molecularly identical). For DD2 only took the prednisolone for 14 weeks as we were worried about the IUGR I experienced with DD1 recurring.

In your position I'd push ahead with treatments and might consider pressing them on Clexane (more powerful blood thinner than aspirin but not without its risks). Was 24 at the time of the losses.

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FrozenNorthPole · 20/02/2011 21:21

PS - meant to say, tests came back clear, but my perspective was that there's a lot they don't understand about the causes of recurrent loss yet, so I wanted to throw absolutely everything I possibly could at the problem.

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cherrychoo · 20/02/2011 21:27

Had IUGR with ds but that was due to pre eclampsia and the fact that my placenta was in a very poor state.

Also suspect that cost comes into focus with the clexane, asprin probably is peanuts in comparrison.
Its all so whooly isnt it!
Because my clotting profile was normal, because everything else was normal, the treatement recomendations were all preceded with "may help"......

Did you find this?

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Havingkittens · 21/02/2011 11:57

I have been taking 5mg Folic Acid for the last 2 years due to loosing 2 pregnancies with fetal abnormalities. Since then, had 2 miscarriages before getting all the blood tests for recurrent miscarriages which all came back clear. Continued with the 5mg Folic Acid and was recommended to take asprin in the next pregnancy on an empirical basis. Had another miscarriage. Contacted the consultant in the RMC clinic about possible benefits of progesterone or HCG supplements during early pregnancy, both ideas were dismissed out of hand as not being effective to prevent miscarriage and was told that they don't offer this treatment for that reason. Am now waiting for NK Cell testing in 3 weeks.

I have read many instances of this protocol working for others, sadly it didn't for me.

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Iggi2011 · 21/02/2011 20:35

Do you mind if I ask, how can I make 5g up from 400ug tablets? (I did google it, honest, still confused!)

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milkyway2007 · 21/02/2011 22:20

Iggi - I think they are saying 5mg - not 5g. Even 5mg would mean taking 12.5 400ug pills a day, which is alot. I am going to be asking my GP about this tomorrow, so will let you know. I think women on high dose folic acid are given a prescription xx

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Iggi2011 · 21/02/2011 22:57

Thanks! I'd have had to start a thread - AIBU to take a full bottle of folic acid every day!
Should really stop all this self-help stuff (though if I don't help myself, who will?!)

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Havingkittens · 22/02/2011 09:27

Yes, I was given it on prescription.

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cherrychoo · 22/02/2011 19:14

Sorry, 5mg, not 5g Blush

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