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Serenity Cream

(95 Posts)
bobsgirl Sat 11-Sep-10 23:00:18

I'm not suffering horrendously but am clearly on the way into menopause. A friend of mine who was suffering badly from mood swings has started using Serenity cream and says it's marvellous.

Has anyone else come across it and what do you think?

purplepeony Sat 11-Sep-10 23:23:42

I bought some but never used it after reading negative reports. I read that no cream that contained amounts of hormone strong enough to have any effect could be sold without a prescription.

If you do some searching online there are conflicting reports. Dr John Lee is an advocate of it and there is another woman dr who is too, but overall it is not rated very highly.

I don't want to dismiss what your fiend has found but it could easily be the placebo effect- especially when it is something like moods.

Fontella Sun 26-Sep-10 10:11:37

Yes, I used it for a while. It's natural progesterone isnt' it? To be honest I can't say it helped or it didnt and after the couple of jars I had bought were used up (this was a couple of years ago) and I paid about £17 quid each over the internet after reading John Lee's book and thinking that the 'oestrogen dominance' theory seemed to match my own symptoms best and it was worth a try. I never bought anymore after that though. It didn't have any adverse effects, but I can't say as it made me feel any better that I was aware of? I just felt the same really and £17 quid a pop seemed a lot for something that didn't seem to be making any difference.

I'm still peri-menopausal, still getting (occasionally erratic) periods at 51, and what I've found works best is to just ride with it. For the past 6 years or so, I've had so many of the classic peri symptoms but what I find is they come for a while ... but (and I know this sounds daft) but if you can just put up with it for a few weeks/months, however long it lasts, then the body seems to take care of it, if that makes any sense, and that symptom fades away.

Admittedly, another symptom may emerge, and it's a bit like fire fighting, but I think as modern women we tend to forget that this time in our lives is entirely natural, same as puberty, childbirth and all the other cycles our body goes through. Yes peri can be a weird and uncomfortable time, but we are equipped to deal with it and with that mindset - I've come through it without too much trouble. Worst thing for me is probably the insomnia, but again, I've learned to live with it. Sometimes I just stay up till the early hours, sometimes I'll read or watch a film if I wake up in the night and not even try to sleep. I've also found (incredibly) that the old wives tail of a sweet, milky drink at bedtime really does work. For me it's proved to be the best sleep aid of the lot but that's a different thread entirely.

izquierda Thu 21-Oct-10 12:10:10

I've posted recently on the subject of recurrent cystitis and just spotted this thread.
I too bought a pot of Serenity hoping it might ease some of my peri- and actual menopausal issues but I too have to say I couldn't identify any tangible benefits and on balance don't think it was a good use of £17.
I agree with Fontella, for most of the issues - hot flushes, night sweats, insomnia, early waking, mood swings, I have found the best way through is to just go with it. The individual symptoms, for me, seem to have come and gone and I have coped, knowing it won't last for ever.
The big overarching issue for me has been the urinary tract problems I've had - see my Recurrent Cystitis thread.
But Serenity? No, wouldn't recommend you spent good money on it.

purplepeony Fri 22-Oct-10 07:55:03

The thing about Serenity is that your dr or gyane could prescribe natural progsterone for you if they think it worked.

My gynae says in his book that to get the right amount from natural progest. you would have to apply bucketfulls.

The other thing to consider is that the latest research into HRT and breast cancer seems to show that it is the progesterone part that causes cancer, not so much the oestrogen, as women who take HRT after a hysterectomy and use just oestrogen, have hardly anyhigher risk of breast cancer.

izquierda Fri 22-Oct-10 16:53:08

I think sometimes, when struggling with all these bodily and psychological changes and ups and downs, you get a bit desperate and this product I seem to recall is promoted quite seriously and persuasively; but yes of course I agree best to get advice from GP or gynaecologist. I am seeing the consultant who did my minor gynae surgery next Monday and this is an issue I plan to question him on.

lamamakat Fri 15-Apr-11 13:36:03

I was very sceptical about using this cream. I was put on HRT Livial by my doctor but extrememly high blood pressure made it imposible for me to continue on it. My night sweats were so bad it kept me from sleeping and all this after I had already gone past the menopause. I have nt had a period for two years and was full of life until these night sweats and hot flushes just hot me.
I started using this cream after trying all other natural remedies and to be honest I have not looked back since. The hot flushes I still get occassionally but the night sweats have gone totally. I no longer have to get up at 3 or 4 in the early hours of the morning to have a shower because I was dripping with perspiration. Maybe it might be psychological I will never know but what I do know is that physically my symptoms are almost gone and I will definitely keep on using and recommending this cream.

cabbageroses Fri 15-Apr-11 16:26:49

lama night sweats etc do not stop after 2 years. When your periods stop you are in menopause for the rest of your life. My Mum had sweats/flushes into her 70s. The time when your periods are all over the place etc is called the peri menopause.

You might try to test the product by stopping and seeing what happens- it may be that you are over the worst anyway and the without the cream you won't have any sweats either?

elektra3 Sat 23-Apr-11 08:06:22

I did a search on the internet for known relief of menapause related symptoms and Serenity Cream seems to pop up everywhere. I wanted independent reviews on the cream and this site came up.

I'm 53 and have recently started experiencing regular night sweats. Not full sweating, just hot flushes (I also get 1 before my period, which I still have regulary). I have been under a lot of stress and this seems to have triggered these regular episodes. I'm losing sleep which is beginning to make me feel depressed and moody. None of these things are a good combination for dealing with stress.

Izquierda, I also get recurring Cystisis and never connected it with menapause. The countless times I have seen my GP about this because the sachets just don't work for me, and I've never been told that this could be a symptom of menapause.

Based on what I'm reading here, paying £17.50 for a cream that appears to have more negative than positive reviews will not be the right option for me.
I'm not saying that it's a hoax, there's just not enough conclusive evidence that this cream works.

kirstygee62 Sun 24-Apr-11 21:37:02

I have been using it for 3 months and it has really helped me. I feel noticeably different. I have less aches and pains, my PMS has almost vanished and my periods have been regular when they were twice a month before. I did experience headaches the first month but that has gone now. I don't care if it is placebo, I'd have eaten rocks if that would have lifted me from the nightmare of perimenopause. The GP had no interest in helping me so I helped myself.

cabbageroses Mon 25-Apr-11 21:12:43

I have researched this online. There is no evidence it works. The National Osteoporosis Society researched it as it is supposed to help with bone density but they found no proof.

Most of the research seems to show it is placebo effect or women's symptoms are declining naturally anyway.

What you will find drs saying is that it could not be sold OTC if it contained enough hormones, and the amount of natural progest. you need is far more than could be in a ot that size.

FattyAcid Sat 21-May-11 07:51:58

bought some last month as recommended by pag and have had improvements to mood, sleep and skin. Definitely worth it for me.

hellofalife Sat 21-May-11 22:09:29

I have ordered the cream today after being on HRT for over 2 yrs with the greatest fear of breast cancer. My mother had breast cancer due to HRT & I really wasn't happy being on it. I have tried on several occasions to come off the medication but after 2-3 weeks my symptoms return. Therefore i'm willing to give this a go, i'll keep you informed of the outcome.

cabbageroses Sun 22-May-11 16:41:51

hell have you tried any supplements such as Menopace?
My gynae has written a book on meno and although he actively supports complementary treatments, i don't think he advocates S cream.

I am really surprised you were given HRT if your mum's cancer was proven to be oestrogen/hormone dependent. it's not advised if a 1st degree relative has had breast cancer.

Euphemia Sun 22-May-11 22:05:50

old wives tail heh heh Freudian slip? grin

posy257 Mon 13-Jun-11 11:20:55

I was having horrendous hot flushes and night sweats for about six months:15-20 flushes during the day and 4-6 sweats at night. They were truly interfering with my life as I poured with perspiration night and day. I couldn't sleep and I could feel myself becoming irritable and irrational. I did a lot of research into the menopause and peri-menopause; I tried Black Kohosh, Sage Leaf, Evening Primrose and Menopace and nothing worked. When I read about Serenity cream and having tried all sorts of other treatments, I thought it was worth a try and I'm so glad I did-I really haven't looked back. In the first 10 days my symptoms had reduced by half and at the end of the first month they had disappeared almost completely. I perhaps have two very minor flushes a month now, where I feel more of a gentle glow rather than a burn and I feel that I have got my life back on track. Why this cream works for some people and not others, I have no idea but I can assure anyone reading this that it IS NOT a placebo effect. NO placebo would have stopped my hot flushes and sweats! I guess we are all different and what suits one doesn't suit another. Pethedine had no pain killing effect on me at all during labour but I know that for some women it's brilliant. It's very easy to dismiss these things out of hand through what we read but I feel that we all have to make our own minds up through trial and error. Slating this cream isn't very fair if it helps some women as it has indeed helped me. We do not have to suffer as our mothers and grand-mothers did. There is help out there. If you can flow through the menopause unaided, then that's fine. I personally didn't want to embark on HRT, for personal reasons, prefering a natural remedy as opposed to a synthetic, man-made one. I'd say give it a try.

strawberryjelly Mon 13-Jun-11 17:11:48

posy it might be worth pointing out that if anything like the cream is going to work, it has to have the same chemical structure as any hormones made in the lab.
I use oestrogen HRt and it is bioidentical- meaning it's the same as what my body produces. End of the day it's still a hormone as is the progesterone in creams made from yams.

EssentialFattyAcid Mon 13-Jun-11 17:16:19

strawb please can you explain what your advice means in practical terms?

I am getting on well with Serenity - does this mean I should stop taking it?

strawberryjelly Mon 13-Jun-11 19:05:37

No- Of course it doesn't mean stop taking it. that is your decision. what I meant was that "natural" doesn't necessarily mean "harmless" or even "harmful". I was trying to say that the chemical composition of what you are using may in fact be no different to the manufactured progesterone ( because that is what it is isn't it- progesterone?) which you could get from a dr.

EssentialFattyAcid Mon 13-Jun-11 22:27:54

Do doctors prescribe progesterone cream? I thought they only did hrt pills?

strawberryjelly Mon 13-Jun-11 22:50:02

drs can prescribe all sorts- especially if you find a gynae or a menopause clinic. if you want natural progersterone you might not find your "average" GP prescribing it but you should be able to source it somehow.

strawberryjelly Mon 13-Jun-11 22:50:55

p.s- there are loads of other ways of getting HRt- notjust pills.. You can get sprays, gels, tablets and implants.

EssentialFattyAcid Tue 14-Jun-11 20:45:28

Thankyou strawb, didn't know any of that. I am quite GP averse but I guess I should get over that!

posy257 Thu 16-Jun-11 11:16:59

Strawberryjelly, your response was a bit confusing! The Serenity Progesterone cream and any other natural progesterone cream, i.e. that derived from yams, is infact bio-identical to the progesterone that we as humans produce in our own bodies. It is not bio-identical to synthetic progesterone produced in a lab. The chemical structure may be similar but anything that is synthetic cannot be the same as something that is natural. If you take perfume as another example, the smell of a rose or a lily of the valley is natural; perfumes that smell of roses or lily of the valley are synthetic. They may well smell the same but they are not the same.
Obviously the oestrogen HRT that you take suits you well and that's good. I prefer to use a natural substance and not a manufactured substance. I guess it's about choice.

strawberryjelly Thu 16-Jun-11 13:08:54

Psoy-- I think you could be mistaken.

What I understand is that the actual molecular structure of anything that is oestrogen or progesterone is the same whether it comes from plants or chemical- plants are in fact made up of chemicals.

Everything is made from chemicals.

eg the ostrogen I use is bio identical meaning it is the same atomically as that produced by my body naturally. Provera for instance was produced from horses' urine and is not bio identical .

but correct me if i am wrong.

posy257 Tue 28-Jun-11 22:00:20

I don't feel that it is my place to correct you-maybe my understanding is different though.
There are natural chemical substances and there are manufactured chemical substances. These two things would have different molecular structures and that's why they are different. Natural progesterone, which comes from yams is natural, it grows naturally and is bio identical to human progesterone. If the progesterone that you use is bio identical then that's good but not all of it is. As you say, there is one produced from horses urine which is not.
Maybe the people to clarify this is the manufacturers of the cream. Wellsprings who produce Serenity have a very good web site-it's worth having a look at.

Annie64 Mon 22-Aug-11 23:31:45

I have always said I would never use HRT EVER however my hot flushes are a nightmare and I burst into tears constantly. I am 51 and havent had a period for 2 years, always been incredibly strong and in control but since the start of menopause just havent felt like myself at all. Added stress of a 17 year old son who has decided to become a child of Satan ( after being the perfect child for about 16 years) and it all adds up to needing something. I have been taking Menopace for months,thought it was working at first and hot flushes disappeared for about 2 months , I was also seeing a homeopath, have tried sage, black cohosh, you name it , Ive tried it. Flushes are constant, day and night but with a history of breast cysts and endometriosis, want to try and avoid HRT at all costs as I know I would worry constantly. I am going to try the cream and will see what it does , if this doesnt work going to try reflexology next....Heres hoping, will let you know if it helps. It certainly wont be the placebo effect if it does work as I'm in a place now where I think nothing will work. Lets see....

ameliagrey Tue 23-Aug-11 08:38:54

Annie- have you been to see a specialist gynae about your symptoms?

I am worried that you are ruling out HRT for reasons that are not valid.

My gynae who I see privately, has written a book on meno and in it- just checked for you- he says anyone with breast cysts or/and endo should not assume HRT is not an option. He says that cysts won't turn cancerous but you may have an increase. Endo may return/get worse but equally may not depending on the type of HRT you take.

Could you go to a menopause clinic( google for ones mear you) or to a gynae for more advice?

If your life is so bad then I think you should not rule out HRT if it were to help.

sallyvictoria Tue 04-Oct-11 17:37:09

Hi all,
Glad I read these posts about Serenity. I am still intrigued and am going to try it, but I am undergoing treatment for stage 2A Hodgkin's Lymphoma right now (ABVD chemotherapy) and at the same time as being diagnosed with cancer, I was told I was perimenopausal. i am 33, have not had periods for 8 months, am not pregnant and do not have any children. I am getting the hot flushes, 10 or so a day and 4-5 at night. I have the insomnia and the bloating, and know that to some extent these symptoms are not related to my disease or side effects of the chemotherapy. Both Gynae doctors I have seen have been pretty unhelpful, only able to tell me that having children is pretty much an impossibility..what about the long term issues??
Does anyone have any advice in terms of alleviating my perimenopausal symptoms? Can I use Serenity alongside chemo, and will it work?
It is enough trying to deal with the chemo side effects, let alone this too!

ameliagrey Tue 04-Oct-11 19:52:41


Really sorry to hear what you are going through- best of luck with your treatment.

You really do need a sympathetic gynae don't you? are you near London or Dorset as my gyane i s great, and I know he would help you.he is a meno and fertility expert, and a director of a fertility clinic.

I doubt if serenity would harm you- whether it would help is another matter. However, you really ought to have help via the NHS for what you are going through.

Can you ask to see another gynae? Ther eis always the option of having your eggs frozen etc.

Bellaciao Fri 28-Oct-11 20:35:25

You can get natural progesterone from your GP provided they will prescribe it - in the form of Cyclogest pessaries so these would be much cheaper than buying expensive cream, and in properly prescribed doses. Also it is of natural origin (yams I think?) but modified to be bioidentical to our own progesterone - so probably similar to the prog cream but more concentrated. I have been using it as part of HRT for several years but apparently not all GPs will prescribe it. It's actually made for use in fertility and post-natal depression but can be used for protecting the uterus when using HRT.
Not everyone's cup of tea though! shock
A friend of mine only used Cyclogest as part of her HRT and never used Oestrogen and she swore by it (placebo or not!). smile

Bellaciao Fri 28-Oct-11 20:38:00

PS I'm new here and sorry I missed all the other posts in the thread before replying and didn't realise it went onto two pages.confused Apologies if I've repeated something or gone off at a tangent not relevant to the discussion.... I was commenting on something way back.... blush

Hotflusher Tue 15-Nov-11 09:22:41

Many thanks for posting this... I have been on Zoladex for 7 months and then had a oophorectomy last week... 7 months of hot flushes, sweats, memory loss, insomnia, slight depression and weight gain. The thought of HRT scares me so when I read about Serenity, it seems worth a try. My only worry is osteoporosis? Do you have to take other vits to combat the onset of this? Thanks

ameliagrey Thu 17-Nov-11 07:59:03

I couldn't let your post go unanswered.

What is the drug you mention and why were you taking it?

if you have had your ovaries removed, why on earth are you not being given proper information and advice by your gynae surgeon?

This is a MAJOR operation with huge implications for your long term health.

Yes, without ovaries you will be plunged into menopause.

without oestrogen- not found in Serenity cream or anything you can buy OTC, your bones will suffer.

How old are you?

if you are post meno then you could do all the things that post meno women must do to prevent osteoprosis- adding calcium, vit D and the right exercise.

However, if you are under 50 it's a no-brainer- you have to take HRT.

If this has been offered and you have refused it- then frankly you are being foolish.

There are risks taking it for more than 5 years but even then the risk is small and the same as drinking one glass of wine a day- in terms of adding to your risk of cancer.

You need to take notice of what I assume your dr has advised.

Delphthelf Sun 01-Jan-12 18:50:46

A good diet can help with the physical symptoms like night sweats ect. Cutting out caffiene and chocolate makes a difference to me (has anyone else noticed this?) and stress definitely makes the symptoms worse. Exercise (I practice yoga regularly) does help to. My biggest problem has been very debilitaing depression which has not been easy to ride as it has blighted my life (well at least until i went on to HRT anyway). I was thinking of trying the serenity cream as i have heard from friends it is good and has worked for them. I think though i will wait as i am about to come off hrt anyway..

dancingqueen1953 Thu 12-Apr-12 19:03:38

I have used Serenity Progesterone cream for years to combat hot flushes and all the nasty things of the menopause. I was also advised to use it by my homeopath for osteoporosis as both my parents suffered from it and I was worried I would also.
I have nothing but praise for the cream, I have sailed through the menopause, no hot flushes, mood swings, or anything else, and at nearly 60, I hope that it is keeping the osteoporosis at bay.
My daughter used it before the birth of her 2nd child, as she had been trying for nearly a year to get pregnant. Within 2 months of using the cream she was pregnant and kept using it until she was 12 weeks. £17 for a tub of cream that lasts 3-4 months is not expensive at all, and I don't believe that it is the placebo effect lasting all these years.

veryannoyedmum Thu 12-Apr-12 22:57:30

Dancingqueenif you are at risk from osteoporosis then surely you are having DEXA scans to assess your bones? if not you ought to.

The National Osteoporosis Society has info on progesterone creams & bone density and they say there is no proof it works.

You may have simply been one of the 25% of women who sail through meno with no symptoms.

I'm sorry but I don't believe in homeopathy either- there is absolutely no real evidence it works. I say this as someone who has spent money on it before- but now I never would.

I have osteoeopenia so have done a lot of research into treatments and what helps- I wouldn't touch Serenity as I think ti's a con.

KT12 Mon 16-Apr-12 19:38:41

I have been looking into alternatives to HRT - another that is advertised is Amberen - has anyone tried it? Any success stories? Some ladies on the forum have suggested Menolieve? I too considered Serenity, but after an extensive internet search I came to the conclusion it probably won't work for me.

At the moment I too am taking the 'ride it out' approach - I regard my hot flushes as power surges! But I am only at the beginning of this journey, so wonder how long I will be able to hold out.

Also when researching the alternatives to HRT and looking at side effects - there are many - some with similar adverse risks. So I agree with the point made that it does not always matter whether you take something natural or man made - both can be equally beneficial or have equal negative risks.

But I am still interested to know about any alternatives to HRT - once again - has anyone used Amberen?

Bluepetticoat Mon 16-Apr-12 22:16:21

What is in Amberen?

Sage tincture is supposedly good for flushes.

If you look at the website and go the the HRT section, you will see the balance and risk chart- with scales. Under age 60 the drs on that site believe that HRT benefits outweigh the risks.

Bluepetticoat Mon 16-Apr-12 22:27:17

I've had a quick look at the Amberen website and the video of how it works. I am not convinced. It uses lots of scientific vocab but I don't think a medic would be convinced. It talks about amber stimulating the hypothalmus and therefore hormone levels being restored- but that won't give you working ovaries with eggs back!

KT12 Sat 12-May-12 18:58:54

My story...periods stopped Feb this year (after relatively regular cycles in the last year however closer together than previously). Together with periods stopping came the most horrendous flushes and night sweats. Then, in the last three weeks or so all symptoms other than no periods have stopped!! No more hot flushes or night sweats - still a bit of insomnia but I put that down to work stress. And I don't take any kind of hormone replacement...also no natural stuff.

I explored alternatives to HRT such as serenity and now wonder for those who say it worked...was it perhaps pure coincidence and without the cream the symptoms would have stopped anyway??

Here's hoping my symptoms stay away - their return however is I know rather likely...

JaneBucks Wed 11-Jul-12 07:49:16

I've been using serenity for 2 years and swear by it. I was really struggling with hot flushes and mood swings. It took a month or so before I felt better but since then despite the odd flush I'm in great shape - even lost a few pounds! Whether its supposed to keep weight off god knows but since using it i've found it much easier to control that menopause tum.

sarahd43 Wed 25-Jul-12 15:19:38

Hi I have just joined and I am seriously looking at getting the Serenity Cream.
I was diagnosed with breast cancer last November. Had surgery, radiotherapy and now on tamoxifen which is pushing me thru to menopause. I guess you could say I am peri? However now I am experiencing the symptoms of the menopause causing me to be bloated, have mood swings, unexplained crying episodes and indeed hot flushes. I want my body to return to normal and wondering if anyone else is in the same situation as me? I am 43!!!!

Ameliagrey Wed 25-Jul-12 20:43:00

Sarah- really sorry to hear about your BC and hope you are in remission.

TBH I don't think you should touch this cream.

There is evidence from expert, respected gynaes which says that the cream is useless- it has not shown to be effective in placebo, double controlled trials.

Most of the results re likely to be placebo, or symptoms that are coming and going anyway- so coincidental.

But- more to the point, if the contents of this cream worked- and there is scientific literature out there saying that yam extract cannot be made into progesterone by the body- then it would not necessarily be a good thing for you to tinker with your hormones, after BC.

Coping with peri or meno after BC is tricky but there are good drs out there who can help you with either traditional or complementary approaches.

If you can afford private treatment or are covered by insurance I will gladly give you names if you want to PM me.

Divinyl Thu 02-Aug-12 21:31:48

I use a similar progesterone cream to Serenity but a different, v well known brand, for fairly violent hormonal symptoms. The docs have called it PMS - it might be but I am fairly sure the build up of physical as well as less tangible symptoms every month (for 7-12 days, so a lot of the month) are not "just" that. I have not been using this very long but I can certainly say that I think it is having observable effects and is not simply a placebo; one which is obvious is the active shortening of the cycle, of the number of days before having a period. This isn't especially desireable or helpful but I think it would flag up the fact that the cream is having an effect as the change has been effected simply by the action of using the cream. Secondly, I feel horrendous on the days I am off it. I' hoping that this is an 'early days' reaction and that this should even out as the hormone builds up. It's more a question of REALLY noticing not using it than what is happening when using it.

The other thing I would add to this is that I'm using this on the advice of a (holistic) hormone specialist, and following tests showing the imbalances of progesterone vs oestrogen, cortisol and testosterone. In addition to the cream I am taking quite a lot of daily omega 3-6-9 and buffered vitamin C, among other things, as well as liver support, because these should also help the metabolism and 'kicking out' of excess oestrogen. I can understand there may be a lot of sceptical reactions to the supplements as well but having tried to research and drill down into what these actually do - effects on enzymes, hormones etc which are not functioning properly, instead of accepting them as vague, optional 'supplements' which are a bit hippyish, I have been pleasantly surprised so far, and am hoping I will notice benefits after some months.

Bellaciao Wed 08-Aug-12 17:48:25

Hi Divinyl. You are using progesterone cream for a different reason than sarahd43. Progesterone is often prescribed for pms as it evens out the hormonal swings that occur throughout the menstrual cycle - which are partly the cause of pms ie the dramatic rise and then fall in progesterone, and the phsiological effects of this (which have a knock on psychological effect).

What is debatable is whether there is sufficient in the dose being taken to make a difference to progesterone levels in the body.

Incidentally one person's reaction to a drug or preparation does not determine whether the effect is placebo - that is the whole point of placebo controlled trials - they need to be done on a large group of women who do not know what they are taking - then if there is a significant effect it is down to the treatment. That is not to deny that the placebo is very important - but just thought I would mention this.

sarahd43 Taking progesterone to control menopausal symptoms of hot flushes, sweats is a whole different area which is definitely in dispute scientifically as ameilagray pointed out.

I would agree with her that if you can go to a specialist who can advise on bc induced menopause that would be very beneficial I am sure.

In addition, if you feel that way inclined maybe ask for referral for cognitive behaviour therapy (CBT) - which a recent trial on women who cannot take HRT due to bc such as yourself - showed to help them cope with hot flushes - even if it did not reduce them.

Good luck and hope you manage to find some helpful practical support.

Ameliagrey Wed 08-Aug-12 18:42:57


You could get progesterone tablets from your dr.

I've mentioned this a lot here- various evidence shows that the skin cannot make progesterone from yams.

The other criticism of these jars of cream is that the "active" ingredient ( if it were) may not be evenly distributed throughout the pot.

There is a kind of " cult" following of this cream, and drs such as Dr John Lee wrote a book about it- but I don't think his claims stand up to scientific scrutiny.

One claim is that it helps bone density- but the National Osteoporosis Society has looked at all the claims and said they can find no positive evidence.

There are good ways to help PMS through diet, exercise and yoga.

ROSEONE Sun 09-Sep-12 16:07:47

These are my experiences, just adding them to maybe help others.

Re Serentiy cream - a god send, it's changed many peri/menopausal symptoms 60% or so to the positive. Give it a couple of months to kick in. Comprehensive booklet comes with order.

PMS - Agnus Castus tincture - inexpensive from an alternative health shop. 30 drops very first thing each morning - very good for irritation. Excellent in combination with Serenity cream. Again give it a couple of months.

Night sweats - black cohosh, 2 caps a.m, 2 caps pm with food for two days - stopped my sweats in their tracks.

Cystitis - I suffered for years with this awful problem but have discovered two things: Mix a good teaspoon of ground cinnamon (ideally organic, easily available at most supermarkets or any health store) with honey into a paste - add hot milk. Apart from knocking out my cystitis it's also a lovely drink! This didn't work so comprehensively for a friend though.

Tips: before intercourse drink water and have a pee. Immediately after intercourse drink water and pee. Not very romantic but it has made a difference for me.

Try keeping feet and lower back warm - sounds crazy but over the years I've discovered that has reduced my 'attacks'.

For Bladder problems in general - excessive loo visits, lack of bladder control, waking up at night to go to the toilet etc I've discovered the wonder of Cayanne pepper (organic is best as additives can affect the outcome). I bought food grade capsules on the web, and carefully (wear gloves) filled a jars worth. I took 2 a.m. and 2 p.m with food. The results (in 4 days) were nothing short of a miracle cure.

I find being receptive to alternatives can be very useful, as can going to a doctor when neccessary. Find what works for you. A very useful sight for all things health related is Earth Clinic - nothing is being sold, no adverts, just people like you and me sending in/asking for advice.

I hope the above is useful - bit of trial and error re amounts and time of course....

Warm wishes,


MissBoPeep Sun 09-Sep-12 16:25:11

Rose I wanted to add some thoughts about your use of pepper etc for your bladder.

I suffer from a very tetchy bladder- known as painful bladder syndome- and control it mainly with diet. The one thing that I cannot tolerate is any spices, alcohol, acidic fruit and juice, and even tea and coffee.

A lot of women have the same condition as I do, but they are not aware of it in name, or what to try to do to help.

I'm just a bit worried that they might read your advice here and make themselves a whole lot worse. But glad you have found some solution.

Bellaciao Sun 09-Sep-12 20:32:46

Well Roseone, like I probably said earlier or elsewhere - nothing like a bit of bio-identical oestrogen to deal with all of these problems in one fell swoop - then you don't have to faff around with unnatural (to us) products like black cohosh whose safety beyond 6 months is in questions. Bladder problems, night sweats, flushes, joint aches - that are due to oestrogen deficiency in menopause. That would be my recommendation to anyone, rather than Serenity Cream. If you need to use progesterone (as you definitely would if adding oestrogen) - I would use the bio-identical one available on NHS.

barbara222 Tue 25-Sep-12 08:07:08

I started using natural progesterone cream back in 2007 when I was diagnosed with very large fibroids (my womb was the size of a 6 mnt preg) the cream did help in several ways ie; less bleeding and pain and PMT. It didn't stop my migraines but may have helped (Lysine works well). I have since had a Hysterectomy 2yrs ago keeping my cervix and ovary's, I use Serentiy which I feel is the best, I haven't had many if any hot flushes. (Im 51)
Natural Progesterone cannot do you any harm as if your body doesn't need it then it wont be absorbed. Use it for three months then decide.
Be warned it can make your periods heavier to start with as it will shed the lining of the womb from the old blood (can be a cause of cancer) and this may put women off initially.
Its always best to do your research.

Bellaciao Tue 25-Sep-12 16:32:23

I agree barbara222 that natural progesterone cream especially at the very small doses in Serenity Cream cannot do any harm at all - but all creams will be absorbed whether you "need" progesterone or not - not sure what you mean by this? Progesterone does have some benefits too as it performs functions in the body besides being one of the reproductive hormones and has a sedative (calming) effect. (A few are progesterone intolerant).

However it is certainly not powerful enough to actually shrink fibroids - at that very small dose. Most fibroids shrink naturally at menopause when oestrogen declines.

In addition there are so many more functions that oestrogen has in the body that I would be wanting to replace this too - especially as you have had a hysterectomy - there are plenty of bio-identical oestrogen products (in fact most of them are). Long term effects of oestrogen deficiency include osteoporosis, vaginal atrophy, bladder and pelvic problems.

These bio-identical oestrogens are as "natural" as Serenity cream - ie have been synthesised in the lab from natural plants such as soy or yam.

Make no mistake - the progesterone in Serenity has been made in the lab to be bio-identical to our own progesterone.

The dosage of progesterone in Serenity is 14 mg per day applied to the skin. Contrast this with the amount many use as part of HRT (to oppose oestrogen's effect on the womb) - which ranges from 100mg - 200 mg - avaliable on NHS as Utrogestan.

MissBoPeep Wed 26-Sep-12 15:51:19

I don't think anyone should self medicate with any hormone except under a dr's care.
If progesterone creme like this one really worked, a) it would be given on the NHS and b) you should take it with a dr's advice- as above.

barbara222 Wed 26-Sep-12 22:07:58

My mother started taking Natural Progesterone in her 70s after repeatedly breaking bones from falling over (she had full Hysterectomy in her 40s with no HRT). She still falls but does not break any bones,by taking natural progesterone, if your body doesn't need it then it is not absorbed.

MissBoPeep Wed 26-Sep-12 22:31:28

Barbaa- lots of points here.
First, if your mum was 20 years post meno she should not have been self medicating with hormones. That's dangerous.

Secondly, the National Osteoporosis Socierty has done extensive research on this and found nothing to support the use of the cream for brittle bones. If it worked it would be a godsend and given to the 1:3 women who have brittle bones.

Third- can you explain how the body only takes up what it needs? There is no progesterone in women's bodies after the menopause so presumably that means allpost meno women take up all of it?

Bellaciao Thu 27-Sep-12 22:58:55

I agree with most of MissBoPeep.

Only - I doubt whether natural progesterone does any harm, and probably does some good - but not where barabra222 thinks. Replacing oestrogen is probably more beneficial in more areas of women's body functions than progesterone. The dose of prog from Serenity cream (if that's what she was using) is minute so can only have a very minor physiological effect.

And barbara222 - sorry but one person's anecdotal experience does not provide scientific evidence that a particular treatment works for a particular problem - (which is why MissBoPeep quoted the Nastional Osteoporosis Society research). You need placebo controlled studies on large populations for that.
I am pleased that your mother hasn't broken any bones recently but if she falls it sounds like some sort of falls prevention would be helpful to minimise the chance of her doing so in future?

creativecatalyst Wed 10-Oct-12 10:23:44

My doctor has prescribed Serenity for me on the NHS in the past but becuase of the cuts they can't do that now so I just order online. It has helped my menopause symptoms and although not much around in the UK a lot of US doctors are in favour and I found some good articles here: that gave me a lot of information.

creativecatalyst Wed 10-Oct-12 10:27:12

It is not the progesterone that is the problem, my doctor tells me, but the synthetic versions in the Pill and HRT. The natural stuff has not been linked to cancer anywhere I can see from bulletin boards or Facebook. I found a lot of really varied experience (good and bad) on this page which helped me:

MissBoPeep Wed 10-Oct-12 18:36:30

Have never, ever heard of Serenity being given on the NHS hmm It's not licensed here which is why you used to be only able to order it "offshore" from the Channel Islands.
Which chemists did you find it in and did you only pay the normal script fee?

MissBoPeep Wed 10-Oct-12 18:37:40

Sorry to be sceptical creative but it's not unknown for people associated with the company to post here under the guise of genuine members.

Glow12345 Mon 05-Nov-12 21:40:55

I have a number of questions and hope you can help. I am peri-menopausal. After 18 months of trying to find natural solution to lack of sleep and hot flushes. Been on Estradiol (oestrogen gel) for 6 months plus the Merino Coil but not really working for me and only went on it to offset general radiating of heat throughout day and especially at night, poor sleep, mood swings and lacklustre. Did not have a period for 6 months before going on HRT but have had a permanent one since! As such, I want to wean off HRT.

1. Has anyone tried Emerita natural bio-identical progesterone cream. What were the results?
2. I have not tried Serenity cream - is it 100% natural bio-identical progesterone?
2. Do GPs prescribe a natural bio-identical progesterone hormone cream rather than a progestatin (Merino coil is the latter which seems to cause me to have a permanent period!)
3. Is there a good menopausal/hormonal balance consultant in North East Hampshire, UK whom I could contact as GP not been able to find solution and gynae tests and blood tests for oestrogen/progesterone levels have not highlighted anything awry.
4. In Germany and the USA, GP's can prescribe natural progesterone cream in sufficient concentration to specific dosage requirements which can make a significant difference to help reduce hot flushes/heat radiation. Has anyone been able to source this within the UK?
4. Anyone heard of DHEA tablets to help offset hormonal imbalances and if so, can these be got in the UK off the counter?

Grateful for any help you can give me any help on any of the above!

Missbopeep Wed 07-Nov-12 21:57:03

If your periods have not stopped for good then the HRT is probably the wrong balance. If your GP gave you the gel and the Mirena he/ she sounds quite up to date as this is the route of choice of some menopause expert gynaes.

The Mirena should stop all bleeding anyway- so my layman's guess is that you have far too much oestrogen. Have you tried reducing the dose?

gardenflowergirl Sun 18-Nov-12 17:07:59

I use bio-identical HRT: estrogel, the bio-identical oestrogen as well as Utrogestan which is a bio-identical progesterone. The problem might be that the synthetic progesterone, levonorgestrel, in the mirena coil doesn't suit you as the progesterone is supposed to modify the build up of the lining in the uterus to prevent heavy periods. Utrogestan is the only bio-identical progesterone licensed in the UK and is available on the NHS. Do your own research on bio-identical hormones and then get back to your GP. This combination works well for me.

gardenflowergirl Sun 18-Nov-12 17:27:39

Glow The other thing is that progesterone cream is an unlicensed medicine in the UK which means that most GP's won't prescribe it, but you can get it from a private GP on a private prescription. You will also have to pay their consultation fee. Dr Shirley Bond in Harley St London or google natural progesterone information service and you can find a list of GP's who specialise in this who are available in the UK.

You can buy DHEA on the internet, but not available in the UK over the counter. I took it for a short while and it helped with energy levels. However, from my own internet research its not something you should take for too long

Hessy49 Wed 28-Nov-12 18:11:12

Hi, my first post on any forum. I had to write about my experience of using Serenity Cream. I am 49, no period for a year and I have tried it since July after having severe flushing and sweats, worst in evenings and mornings. Previously tried HRT but started having bleeding for week plus at a time so stopped after 3 months. Also tried Fluoxetene, ( prozac) which helped a bit but didn't want to take long term so have stopped this. I was very doubtful about trying Serenity and cost but I have honestly had great success with it. Took a couple of weeks to help but has really minimised symptoms. When I ran out of cream for a week, I noticed return of symptoms and took a week or two to reduce again once new supply arrived. I have just recommended to my very sceptical friend and she is going to try it. I really don't think effect is placebo but admit it could be coincidence that symptoms have greatly reduced. Will keep you posted.

Pamel Tue 08-Jan-13 13:09:19

Serenity worked for me. Also Menopace Plus is good.

norgeforlife Fri 11-Jan-13 15:23:52

I have been on HRT on and off since my periods stopped 10 years ago. Each time I came off the drug my hot flushes returned with a vengeance. I wrongly assumed that after a certain age this would automatically adjust and I would feel back to normal but not the case for me I'm afraid. Its 2 years since I have taken the HRT (I got it down to one every 4 days and felt well but at nearly 60 felt it was pushing my luck as my Aunty had had breast cancer) and I am still having the sleepless nights etc but have now resigned myself to the fact that it may be a long time before I feel really well again.

Momos Thu 14-Feb-13 16:06:46

I've been using it for 3 weeks now and it's amazing, I'm 45 and suffered badly from hot flushes during the day and was being woken 4-5 times a night with sweats, I've been having 2 menstrual cycles a year. I noticed results from day 1 when I felt a flush coming but didn't amount to anything and had a sound full nights sleep. I have had no flushes or sweats since. This cream has given me my normal life back, I'm less tired and depressed due to the lack of sleep I was having and no more uncomfortable hot glad I found this cream.

Grannylipstick Mon 01-Apr-13 20:38:03

I have just bought this cream. No in st ructions have come with it. Where do I put it????

Bellaciao Wed 03-Apr-13 15:47:17

It really doesn't matter because at best it is a very weak bio-identical progesterone, and is not going to deal with long term effects of oestrogen deficiency - but might make you feel as if you are doing yourself some good. Depending on the make, at worst it could be a compound that can't be converted into bio-identical progesterone in the body so will do nothing. I would look on Google. What are you wanting to use it for?

Toptotoe Sat 06-Apr-13 22:51:14

I've been using Serenity for a week now to help with peri symptoms. I think it's working but it's early days. What I would ask all the nay sayers out there is - if it's so ineffective and contains so little progesterone then why is it banned in this country?

Missbopeep Sun 07-Apr-13 18:22:09

Because you can't prove a negative!

And no supplier is going to ask for a licence for their product on the grounds it doesn't work.

It's sold as HRT/hormones. No one in the UK is allowed to sell anything that is a hormone treatment over the counter.

All the evidence it works is anecdotal, or placebo effect, from my research.

Even prescribed drugs have a 33% placebo effect- it's a very powerful thing, believing something will work. And hormones are so all over the place during peri that is maybe why some women think it works.

creativecatalyst Wed 10-Apr-13 12:13:09

It isn't banned, in fact a number of GP's do prescribe it, but because it is a natural medicine you need a prescription.

creativecatalyst Wed 10-Apr-13 12:14:22

they sent me a link with my confirmation email, but you should find it on their website for a free booklet. Think it is

creativecatalyst Wed 10-Apr-13 12:16:01

I didn't think HRT had progesteorne - other than the mare's urine one? They are mostly synthetic aren't they?

missbopeep Wed 10-Apr-13 22:46:13

If GPs prescribe Serenity then why are women paying £20 or so to have it sent from the Channel Islands?

I think you are confused creative.

GPs can prescribe natural progesterone as tablets for example- I think very few would prescribe cream and I have been told that the amount you need as a cream to have any effect would be massive and not acceptable in use.

HRT is given as 2 hormones- oestrogen and progestins ( progesterone is what we make ourselves- progestins are man made,)

Unless you have a uterus you need to take progestins for part of each month, or every 2 or 3 months depending on what your dr has advised. This is to ensure the lining of the uterus does not grow too much with the oestrogen, which can lead to endometrial hyperplasia and possibly cancer.

Oestrogen sometimes is made with mares urine- the HRT made in the US called premarin is- but there is a lot of HRT that is not made with it- in fact most. it is made from bio identical substances which mean the oestrogen is the same- molecular structure- as that we produce ourselves.

missbopeep Wed 10-Apr-13 22:47:11

sorry- typo- should read unless you don't have a uterus....'

JaneBucks Thu 11-Apr-13 10:44:41

Hi there, I was prescribed natural progesterone by my GP. It worked well. I used it for 3 years until I was through the worst. I went to him because I was worried about the cancer risks of HRT tablets. About 10 years ago there was a damning report that came out, some major study that identified big risk of breast cancer. Anyway I'd read something about natural progesterone and told him. He seemed quite happy to prescribe it. I'm just amazed we're still be prescribed pills that have such dangerous side effects.

missbopeep Thu 11-Apr-13 15:30:57

Jane- the latest thinking is that it is the progesterone which is the link with breast cancer.

What did your dr prescribe- can you name it? Be good to know.

Women who take combined HRT- both hormones- have a slightly higher risk, but women who take only oestrogen actually have a lower risk of breast cancer.

The research you are talking about- Million Women and the other one- have been pretty much ditched now in terms of research as they were shown to be flawed. It's all about risks and balancing risks with benefits- do you agree?

I'd be interested to know which progesterone you took- was it the equivalent of the mini pill?

Also- HRT as a tablet is just one type of HRT- there are lots of others which are safer for some side effects. I know lots of women on HRT but none of them actually swallows tablets!

missbopeep Thu 11-Apr-13 15:33:50

Jane you posted in July 12 to say you had been using Serenity for 2 years. Was this what your dr gave you? As these are your only posts on MN it makes me wonder- just a little- if you work for the company?

Soopie Mon 22-Apr-13 15:41:54

I've read some extraordinary things on here, such as "strawberry" saying that Provera is made of horse's urine! No, it is not! Provera is a synthetic hormone that is not bio-identical and has many side effects that are very harmful to the body and can cause - amongst other things - cancer! Premarin was made from horse's urine and was equally as bad for us because it is not bio-identical and doesn't contain much that our human bodies would need/could use! I use Serenity and I have to say that I feel much better on it (no menopausal symptoms). I would NEVER take HRT because of the many risks attached to it (it IS synthetic and not what our bodies need!). Everyone can decide for themselves, but please read up on the pros and cons instead of just taking various people's points of view, when they often do not reflect reality or are misinformed.

Missbopeep Mon 22-Apr-13 16:22:16

Whenever there are any discussions about products that you buy ( as opposed to ones prescribed) 'unknown' posters come along extolling the virtues of the products. I can't help but be cynical and wonder if they are from the companies- especially when they have no other history on the forum at all. hmm

HRT can be made from natural substances too.
Would you like to tell us more about what you understand by the 'risks' in terms of a woman's absolute risk re. age and use of HRT? Interested to know what your take on it is.

Elenkalubleton Tue 13-Aug-13 14:10:07

Does progesterone creme act as a lubricant I'm suffering from really itchy bits tried prescribed zinc / castor oil cream no good.any advice appreciated.

Missbopeep Tue 13-Aug-13 16:54:16

No. The itching is due to loss of oestrogen.

You need to see your GP and ask for either Ovestin or Vagifem cream or pessaries which you use for several weeks to reverse the process.

lisamichelle46 Wed 28-Aug-13 21:08:02

I have been taking ELLESTE DUET 1mg tablets (HRT) for almost 3 months now, after a week or so i started with really bad headaches which I have never experienced before also heavier periods and my hot flushes have not subsided at all, my nood swings if anything are worse, I seem to be experiencing certain side effects but no benefits, could anyone give me ant feed back about these tablets?

lisamichelle46 Wed 28-Aug-13 21:24:25

If anyone could suggest any alternatives that have worked for then I would be grateful.

westfossil Wed 27-Nov-13 18:50:34

I started to suffer with hot flushes at night and during the day which rapidly got worse. Some nights I'd wake up and wonder what had disturbed my sleep and then the heat would begin to rise until it felt as if I was in sauna. I can't take HRT, not that I'd want to, so I thought I would try cutting out certain foods and see if that made a difference. Unfortunately it seems my triggers are wine wine and chocolate! What a blow! Still, it works for me.

jessiflecher1961 Wed 08-Jan-14 11:07:24

Hi, iv'e been reading what the general view is about serenity as i'm not sure if it will help or not, i get loads of hot flushes and night sweats and am sick of it, i had a hysterectomy 6 yrs ago, i also get really bad joint pains , which iv'e had for 2 yrs, which they also said was down to menopause, there now saying it might be fibromyalgia,
so if i could just get rid of the hot flushes, it would make me feel so much better, im 52.

Jaffacakesallround Thu 09-Jan-14 13:24:56

I'm a bit sceptical about this product really, simply because you can get bio identical progesterone ( tablets) from your dr on the NHS if it was going to help menopausal symptoms- but the main meno symptoms are due to oestrogen deficiency. No one has any progesterone post menopause, so I'm at a loss to see how adding it on its own is going to do anything other than the placebo effect.

osbornesl Wed 12-Feb-14 05:34:42

i have just bought this cream . Before I purchased it , I sent serenity cream an e- mail asking if it was safe for me to use.I told them I had a full hysterectomy (overies removed as well ) And that I had HAD breast cancer which was estrogen receptive positive . They assured me it was safe for me to use . My doctor doesn't want me taking HRT. So does anyone know if this cream is safe for someone who shouldn't take HRT .

marlena1211 Wed 30-Apr-14 19:57:06

jaffacakes apparently hormones in the body constantly morph into one another i.e dhea morphs into oestrogens and testosterone (or alike) and progesterone can transform at least partly into oestrogens as well, this is why thgs are not equal for every woman.

The cortisol induced by prolonged stress is a factor as well, as is the state of the adrenal glands whether they do their job or not etc.

it is more complex than a simple fixed recipee oestradiol/progesterone/testosterone.

besides there are loads of different types of oestrogens each with their effect.

Spam66 Tue 13-May-14 09:28:34

Have just stopped HRT which was a miracle cure for terrible menopausal symptoms as had heart attack 2 weeks ago at age of 48! Cardiologist advised I should stop it, but felt it was inconclusive that it contributed to me having my heart attack. Serenity was suggested by one of the cardiac ward nurses, so decided to do some research. Seems to work for some but not others. Had my first bad night last night with insomnia and night sweats in about two years, so may give it a try.

jonahzinny Tue 27-May-14 15:54:04

I have just ordered my first jar after being advised by Dr Peatfield. I have adrenal insufficiency and moderate hypothyroidism. He advised on using this particular cream as this can often be an issue for many women and my symptoms pointed in this direction. From what I have read it seem to makes a big difference knowing when to use the cream during your cycle, I think its 14 days before period begins? same as taking Agnus Castus Berry. I agree finding a root cause to your issues is vital. Candida is also something worth reading up on! Dr David Brownstien and Dr Barry Durrant-Peatfields books are a very interesting and insightful read with regards to our hormones (both holistic doctors) Having the knowledge enables you to decide for yourself what might be best. We each respond in different ways so its important to try for yourself. You can find what works best for you right now, but our bodies do continue to change, even emotional stress impact hugely on our gland functioning. Hypothyroidism can often be a root cause with regards to many hormonal issues, although it seems to go undiagnosed. I will see how I get on with this cream!

Wendy64 Fri 04-Jul-14 20:33:01

Hi, I have been using it for a few years now, it took my 19 day cycle up to 26-28 days and eased cramps and heaviness. I haven't been able to afford it for a while and had forgotten how badly I used to suffer. I have had two periods in 30 days and the cramping last time was pretty bad, along with very heavy loss (sorry to be explicit), so I'll be getting some as soon as I can!

bibijay Sat 20-Sep-14 18:44:56

I haven't used Serenity, but have been using the Life-Flo Progest cream for about 5 years. I am stopping it as I don't believe it makes any real difference to my symptoms and it is very expensive. I found this article online which might be useful-
All the other info about natural progesterone creams seems to be from people selling it, which of course is not reliable or objective.
Personally I think if you're not well off its a waste of money, buy yourself a lipstick or a nice pair of knickers once a month instead, it'll do you more good.

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