Really depends on the amount of money your mother wants to spend. Singapore has many luxury hotels. Personally I find both The Mandarin Oriental and The Conrad to be very good. These are closer to the CBD. The Mandarin Orchard is positioned right off the main street and may be better for shopping and restaurants. If money is not an issue perhaps she would enjoy The Fullerton or Raffles, both are luxurious without the design hotel feel. (also Sunday brunch at the Fullerton is to die for!)
My mum is going to Australia in April, travelling alone and I was wondering if anyone could recommend a hotel for her to stay in for her 2 night stop over in Singapore. She is 70 so doesn't want a budget backpacker type place. Any ideas gratefully received as I am concerned she is just going by photos on the net with no knowledge of the place at all!