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Mirtazapine and weight gain

(41 Posts)
Maisiethemorningsidecat Sun 11-Jul-10 16:43:56

I've been on these for a few months now - only 15mg - but omg the weight gain is really getting me down. I've put on at least half a stone (OK, nearer one stone), and for someone who's always weighed 8 stone I now have nothing that fits and am actually feeling low again because of the weight gain. I know I'm being very vain and shallow, but I'm 41 and beginning to feel very frumpy anyway, and although I'm still eating healthily it's still piling on.

Has anyone stopped taking it and reverted back to their normal weight?

Chrisstubbs26 Mon 24-Feb-14 09:36:43

Hi, I've been reading this thread, I started taking this AD two weeks ago I also started at my local gym, I have not lost any weight, does anyone know if this will wear off as due to my depression(grief over losing my mum) I was eating anything and everything, I have now stopped eating rubbish but the weight is not budging, I'm hoping this isn't the case as the AD seems to be working please give me good news :-)

DiaryOfAWimpyMum Sun 21-Jul-13 10:57:34

Poodle please stop panicking Mitrazipine do not make you fat upon sight of them, they give you more of an appetite and if you eat the wrong food, yes you will put on weight.

I have been on them 3 times, 1st time I went from and 8 up to a 14/16, I lost the weight after a few months after being unwell with a horrid stomach bug.

I needed to go back on them January last year for sleep so did so and bought in only healthy foods and walked the dog 3 times per day and only gained 3lbs, .

The final time was in November last year to a few months ago and I gained weight but was very conscious that I was eating total crap and wasn't moving much either (ie walking dog or any exercise).

If you have an eating disorder this is why you may have been given them, they help with anorexia etc.

Usually if you are depressed you may not eat, these give you an appetite but if you eat well (healthy) you need not put on weight.

Funnyfishface Sun 21-Jul-13 00:31:11

Hi all.

I am on citalopram for anxiety. Started October 2012 and have gained 10lbs. From 8stone 8 to 9 stone 4. I am on a calorie counting diet which is getting me down. It's all around my middle.

The go says weight gain is not a side effect but I have never had a weight problem and this makes me very miserable. It's making me want to stop them. I'm only on 10 mg

Ragusa Sat 20-Jul-13 13:25:00

poodle what?!? Mirtazapine is notorious for causing weight gain. Like you say, it even says it on the PIL.

Please don't just stop taking it all of a sudden though. Is there no-one you can see on Monday. I think you are unlikely to put on weight between now and Tuesday so don't panic.

PoodleFlavouredFreddos Fri 19-Jul-13 23:59:42

if i don't take my dose tomorrow will i suffer any withdrawal? I have only been on 15 mg fortwo weeks, but I can;t call my cpn until tuesday & what if it makes me gain weight over that period?

PoodleFlavouredFreddos Fri 19-Jul-13 23:55:44

oh please please no.
I have been on 15 mg of mitazipne for two weeks.
I have an eating disorder and I can't gain weight, I can't. My cpn told me it was 'unlikely' but reading this thread i'm going to ask about other options. I am on other anti psychotic medications that has caused weight gain in the past & i really can't do that again.

how quickly does the weight gain start?

Ragusa Fri 19-Jul-13 21:18:41

Orchidlady, sorry your DP is struggling but just to say he may not have 'slipped back', he may have had withdrawal symptoms. Meds like Mirtazapine need to be tapered off slowly to avoid rebound anxiety and depression. If he is cheesed off with weight gain, he can tell the GP and maybe could try something else.

Orchidlady Thu 18-Jul-13 09:55:25

Just stumbled across this thread, my DP in 30mg for past year and put on loads of weight, he has always been slim so very new to him and making him very unhappy, now depressed about being over weight. He "forgot" to take them for a week and what a massive difference, he has slipped right back, so obviously needs his pills. sad

Beckyb0027 Thu 20-Jun-13 08:12:53

Hi just seen this thread. I have been on Mirtazapine for about a year and started on 15mg before going up to 45mg. I am now weaning off them and am down to 7.5mg. They did the truck for me in terms of helping with the depression, that coupled with a fantastic counsellor!!
I have however gained over a stone and the appetite is ridiculous. My GP told me that the lower doses are worse than the higher doses in terms of side effects and he is right, I am still gaining weight!

I just hope that once I come off them completely the weight will start to come off again. Some of your comments have given me some hope that it will. Mind you I think I would rather be overweight and feel happy than be in the rotten place I was in last year.

lilruthie Sat 02-Oct-10 16:56:53

hi there i was on it for 8mnths and yes hun i put loads of weight on n just couldn't function on them all i wanted to do was sleep n eat but good news is when i got taken off them n tried another AD i lost my weight very quickly so speaking from my experience hun yes you should lose the weight pretty quickly if you have to stop taking them for any reason.

I'm just really scared of making things worse. maybe in a week or so, when I've got less on I might try it for a week. perhaps. I'm not sure, this week I've turned into a dithery idiot who can't even decide which sandwich bag to use.

MamaLeMay Fri 24-Sep-10 13:43:39

ohyoubadbadkitten, I'm feeling exactly the same as you! my GP changed me from fluorexine as it didn't help my anxiety and was making me REALLY sweat.... I googled about these and have been so worried by everyones reaction to them; weight gain and feeling 'zombied' the next day , that I've been too scared to even start them?! My youngest ds is nearly 4 months and I want to lose my pregnancy weight so it's shocked me that practically 9 out of 10 reviews I've read on the Internet have all said that they gained ALOT of weight....confused

OhYouBadBadKitten please give it a try? Your Dr. would not have given it if she didn't think you needed it.

As I said earlier on this thread I have been on it since June 09 and have not gained weight. It has by far and away been the most helpful of the (many) drugs I have tried in the past in terms of tacking depression / anxiety,.

Been prescribed this today by a new gp. Not been warned about weight gain at all and as gaining weight is a big fear of mine that only comes into play when I'm anxious/depressed I don't think she made the right call. Perhaps if she had actually asked about my symptoms rather than just toting up the score on the depression form she would have discovered that.
so, not going to take the stuff.

Oh dear you have been through such a lot. You must be such a strong person. Well done for persevering, and wonderful you have ended up with two DDs despite being told you may never have any children.

PND is hideous isn't it. Mine seemed to rumble on for ages too, and still have traces of it 3 years on, though I am so much better than I was.

You are so right re. the insulin thing. A friend of mine has epilepsy and took her epilepsy medication all through pregnancy.

I don't think there is such a stigma with other illnesses. This same friend said, when we were discussing the subject of medication during pregnancy, "yeah but you wouldn't want to take something if it wasn't, like, for a real illness" hmm

I did speak to the dr. about mirtazapine in pregnancy. She said she was going to go to the National tetrology service to try and get the most up-to-date info on the evidence. However, she has not got back to me and that was nearly 2 months ago. She did say it would take some time, so am hesitant to badger her. Just not assertive enough!

MrsThisIsTheCadillacOfNailguns Mon 20-Sep-10 12:26:25

I'd like to think I can stay off them,but in reality,I'm not so sure.I had problems with depression in my teens,then no trouble at all until I lost a baby before having dd1,when I was 34.[was very complicated as we'd had fertility problems prior to this].After that I spiralled,due to being told that the fact we'd conceived at all was a miracle,and that our already slim chance of having a baby were now virtually nil.

Anyway,bloodymindedness is my middle namegrin I had dd1 and had very bad PND afterwards,and thinking about it,have not had a long period of time since then without depression/anxiety.In fact I was taking Fluoxetine [for all the good it did] when I became pregnant with dd2.I seem to manage for a few months,then get unwell again and it has been like this for 8 years now.

I suppose that if I had to take Insulin every day,I wouldn't feel bad about it,so why should I feel bad about anti-ds? If things start going badly I'll ask to go back on them again,weight or no weight.

Have you spoken to your Dr about taking Mirtazipine during pregnancy? It is hard isn't it?-a fine line between functioning well and possible affects on the baby.

I have to go back to work I'm afraid,I was half hoping that it would rain so that I wouldn't have to go.I'll pop back here later.

Hi there Mrs. We want to try for another baby soon, so am in a bit of a dilemma...

stay on a really low dose and (hopefully) stay well


Come off them completely, get pregnant and risk crashing and going into a bit of a crisis...

Hmm, don't really know. If I weren't planning another baby I don't think I'd have a problem staying on them long term.

How about you?

MrsThisIsTheCadillacOfNailguns Sun 19-Sep-10 20:50:38

shock at the Citalopram.That would have finished me off,I have a phobia about sick.

You are doing really well to manage on such a small dose.Do you mind me asking if you are going to keep taking it for the forseeable future?A friend who is a CPN said that there is no reason not to take it long term if it suits.

I actually am down to 7.5mg now, and find I can still sleep on that. You may be able to get down to that dose too, find it still helps you sleep but doesn't have such an effect on your weight.

Yes I had that with citalopram too - terrible agitation. Was also violently sick on them, and it made me so much worse. Yuk yuk.

MrsThisIsTheCadillacOfNailguns Sat 18-Sep-10 21:57:23

Oh that is interesting.I agree about the sleep thing-it is wonderful going to bed and knowing that you will sleep.I actually look forward to going to bed now.Thank you for telling me about the lack of weight gain on 15mg as it is reassuring if I don't manage to cope well without taking the drug.

I think it was Citalopram which gave me muscle twitches. It was like having restless legs,but all over.After 2 nights of jerking about like someone was pulling my strings,I went back to the Drs and asked for something else.Nasty stuff.

Hi there Mrs you may find that the weight starts dropping off on 15mg.

I have never taken more than 15mg and my weight has not increased significantly at all from where it was when I started.

I've been taking it since June 2009. I did notice an increase in appetite at first, but I think like all side effects, it starts to level off after a while.

I am still 8 stone and about 4-5lbs.

I too have tried other ADs and none of them worked for me (citalopram was evil and lofepramine gave me an awful dry mouth and the chemical taste of the tablets made me wretch horribly).

Mirtazapine did wonders for my sleep. Even now I am wondering how I will cope without them.

MrsThisIsTheCadillacOfNailguns Sat 18-Sep-10 08:19:28

GetDownYouWillFall,I'm on 30mg.I saw my GP yesterday and because I'm feeling so well,and have been on them nearly a year,we have decided that the time is right to wean myself off them,so am going down to 15mg.

However,I am under no illusions-if I start sliding down again I'll go back on them-better fat and happy than thin and miserable I suppose.I did mention the weight gain to my GP and he laughed and said that no one ever loses weight whilst on Mirtazipine,it is famous for weight gain.He also says that eventually the weight gain will start to plateau-but when it does that is unpredictable.

Apart from that,it has worked really well for me,sorted out my insomnia and anxiety a treat.I've taken Fluoxetine and various other drugs in the past and they have either not worked or had nasty side affects.Mirtazipine is the best of the bunch as far as I'm concerned.

Hi MrsThisIsTheCadillacOfNailguns - what dose do you take?

MrsThisIsTheCadillacOfNailguns Thu 16-Sep-10 23:42:13

Only just spotted this thread and was amazed.
Maisie you could have been describing me.I was 8st 7 when I started taking Mirtazpine last Nov and am now 10st2lb.Like you I was a tiny size 8-10 and never put weight on,and for a start I was quite pleased with a bigger bust,but not the bigger thighs,waist,bum arms ect.It is really getting me down now,because none of my clothes fit properly and it feels horrible that my thighs rub together and that my stomach hangs over my jeans.I do an active job and took up cycling,stopped eating between meals despite feeling so hungry that my stomach hurt,but still the weight is piling on.Other than that,the drug has really helped me feel better,but I'm starting to get miserable about being so hungry all the time and getting steadily bigger.I can't afford and don't want to buy new clothes because I'm too fat for my old ones.

Did you speak to your GP and change your medication? I'd be interested to know if you lost any weight after stopping Mirtazipine.

Maisiethemorningsidecat Mon 12-Jul-10 20:14:45

Thank you so much, all of you - you don't know how much these posts mean to me (OK, indulge me - I'm a bit of a wreck at the moment grin). I thought I was going to get shot down in flames for being so shallow, but it's been so lovely to have supportive posts from people who have been through the same thing.

I'm really interested in the tri-cyclic ones that have been mentioned, so will put my information manager skills to the test and do a bit of research.

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