It depends on the exact wording of the personal guarantee.
They may attach a charge to your house that has to be discharged if you sell it. They may already have a charge on your house. The bank may not be able to call in the charge or be able to force you to sell but unless you pay off the debt it stays attached with the debt accumulating interest until you sell your house or you die.
You need to look at the exact wording. You need legal advice. It may even be that a court might decide that you were misled.
It may be that the bank tries to force/persuade you to sell your house to pay off the business debt by taking out a mortgage on your house. Do NOT agree to that. Many business people do that in desperation to try and keep the business afloat and then lose their house 18 months later. Once a bank has enforceable security via a mortgage you really have nowhere to go.
Letting the business fail if the bank have no enforceable charge on your house might be a much better solution.