Hope you see this clwc!

Haven't been on here for ages and just looked for this thread.

I didn't ov on Clomid last month - progesterone was 4 on CD42 and AF started on CD52 so I am now CD10 of a new cycle and have taken my last Clomid. Just waiting yet again. I had reflexology last time so am trying to get booked in for some more but that won't be for a couple of weeks.

Not too bothered at the minute, just enjoying the summer hols with DS doing lots of things I wouldn't be able to do easily if I were pg or had a baby (bowling/ice skating/lots of days out) enjoying our freedom.

Hope you are well, keep in touch.

Sorry for the name change, don't like to have same name too long! Bit paranoid!

XXX

Sorry, the thread disappeared off my radar.
So, Josie123 = SockThing?
Did you ovulate this month?
My period started last Saturday. I'm hpoing it'll stop soon. I miss the BDing!

I am sock thing!

Ahh that's a bit of a let down, your appointment being pushed back. I know how you feel on the waiting waiting waiting. I can't imagine what it feels like to have a proper cycle and be able to track ovulation and know when you are due to come on AF, it would be fab!

I am CD27 today but not waiting for AF! Hoping to OV at some point. Wishful thinking! We both need to just keep BDing and waiting! Combined with my low HCG levels I will be 14 weeks before I know it again I bet!!! I want to know nice and early next time!

Keep in touch!

Hello SockThing

Long time no see. I'm OK. I'm approximately CD 40 now. Had some spotting yesterday, nothing today, feel out of sorts, numerous BFNs, still no proper period. Don't think I ov'd last month. My cons appointment has been pushed back from the 3rd to the 31st July. So I guess I'm just waiting for things to get going. x x x x

Hi
Mowmi, I was reading your post and hoping you were going to say things turned out well, I am so pleased you had a positive scan and I hope everything progresses as it should and you have a happy & healthy 9 months! I am so envious of ladies who have a "cycle" and can test on a certain date and get a +ve or -ve and know for sure!

I had my scan today to see what is going on inside me and (bearing in mind I am on CD21 of a 50mg Clomid cycle) there wasn't much activity! The sonographer said by CD21 on a "normal" 28 day cycle she would expect to see the collapsed follicle where the egg had been released last week but she could only see lots of small follicles - immature eggs I guess. She said there is no dominant follicle ripening to ovulate either

Feel quite down now after the elation of having AF on my own and taking Clomid.

I am going to carry on BDing 2-3 times a week and try not to obsess as I know I am not going to ov in the next week or so so there is no pressure. Then wait for next AF I guess. It has happened for me before and I know I ov'd late on then (about day 35 I think) so I have to just hope I am a late ov'er - if there is such a thing!

How are things with you clwc?

X

Bump

Thank-you for 'stumbling', mowmi

It sounds as though you have been through a heck of a lot to get to where you are now. Congratulations on your BFP!

GPs are difficult creatures. I explained to one GP that I would like to be prescribed Met. She said I'd have to get it from the FC, but also that you shouldn't take it when pg. I told her that I didn't agree because Met helps with progesterone levels, or something. I just wish I could speak to someone who knows what they're talking about, and also takes me seriously.

Take care xx

Hello Ladies, Just stumbled on your thread by accident - what you are talking about makes sense to me...

I'll try to be brief....!

diagnosed pcos after ttc for about a year (knew something was wrong because my cycles were so long - sometimes 70 days +)
Was put on Metformin and sent down the IVF route because of DP's slightly low normality sperm count.
Not long after this DH was diagnosed with testicular cancer so IVF was put on hold.
In the meantime I did Metformin and accupunture and within a few months cycles settled down to 36 days and I got EWCM every month which I know isn't conclusive but a fairly good indication of ovulation?
DH's treatment included chemo which gave him 50/50 chance of infertility so we carried on down down the IVF route with frozen sperm.
We had 2 attempts - first didn't work, 2nd did but had a really slow hcg rise which ended up in mc at 8 weeks (never progressed past gestational sac)
Through all this carried on with metformin (cycles kept stable at 36 days bar a little blip after mc)
A couple of weeks ago we were due to make an appointment to see if the chemo had effected DH's fertiltity further when I felt aware of tingling in my boobs... did a test and to my massive surprise I was pregnant!!
I haven't had my hcg measured but I've been using the cb conception indicators tests and It seems to be climbing as it should?
Had a scan at what I thought was dead on 6 weeks only to see another empty sac (throughly devastated at the prospect of exactly the same thing happening again!)
On thursday I begged my GP to get me in to the EPAU unit so they could confirm mc and help me sort it out... to my total shock and delight was a little yolk sac, baby and heartbeat - que tears! My dates were 4 days out and that made all the difference.
I'm still worried that pcos puts me at increased risk of mc but I feel that the odds of that have slipped at least a little.
Going to carry on with the metformin until 3 months and hope it helps keep this bean sticky!!

I wish you lots of luck in your quests x

Ah. I see.

I've read that Met should be introduced gradually, e.g. 250mg each day for the first week, 500 for the second, etc. Then the side effects aren't as severe. I'd like to be on it, in case I do fall pg, so that I have a better chance of producing the required hCG to carry the pg to term, rather than m/c-ing in the first few weeks.

I don't suffer with bad acne, but being overweight from insulin resistance has caused a few skin complaints that I'm none too proud of. My cycles have been regular for the past few years, in that I get PMT every month, I want to 'do the deed' at certain times every month, and I have a couple of extra spots just before AF time... But AF often doesn't come. Everything but the actual period. It's weird. And it has been the same since puberty; before I started to gain weight.

Ah no, the u/s was because I hadn't had AF since starting Met so it was just a look inside IYSWIM. It has coincided with being CD21 thats all. The only monitoring on Clomid I am having is the CD21 blood test.

I've never had the progesterone before and didn't really want to take it so I am so chuffed I didn't need to. Last time I had cycles of 50ish days on Met alone.

I have lost a bit of weight through Met, mainly loss of appetite rather than the dreaded "met" belly. I haven't had bad side effects on it although I am not overweight, thats not one of my PCOS symptoms - its acne and no AF for me!!

I hope they give you Met, its brilliant.

Nice one! Did you always have to take Norethoojamawotsit progesterone before?

I wasn't monitored whilst on Clomid. It's strange that you're getting such a late u/s scan. They're normally for monitoring follicle size pre-ov. Then the CD21 bloods are to see if you have already ov'd. Hm.

Have you lost weight on Metformin? I'm hoping I will... That is, if they let me have it

Hi

I love Metformin! After 114 days I had AF without having to use the Norethisterone! So I am now CD5 and on day 4 of Clomid eeek!

Having u/s scan on 17 June which will be CD21 (originally booked to see what was going on with my ovaries, maybe will hopefully tell me if I am going to ov?) and CD21 blood test same day.

Just thought I would let you know as I am so chuffed I didn't have to take the Norethisterone.

x

Great news, Suzi

Best of luck with Clomid. I hope it works for you really quickly. xx

well ladies, had my appointment today and i will be getting the clomid treatment.... got to go to a fertility clinic for another few tests first, so hopefully i will get started soon

it feels good when you know somethings getting done!!

how is everyone?

thanks ladies

your so right about being persistent butterfly, i dont know how many times ive argued with the doctors to do more tests... and the hospital and gp keep passing me about. sometimes you think they cant be bothered.

cant believe they never monitored you Clwc, that must have been frustrating. thanks for the advice

And last, but not least... Nice to see you back, SockThing xx

Hello Tigress

Did your consultant mean OPKs when s/he said 'pee sticks'? I have read many times that PCOS throws OPKs off, especially if you are taking Clomid, but some women claim that they still work for them. I think a lot of this TTC malarkey is pot luck, especially for us PCOSers

If s/he meant HPTs, then it's interesting to hear someone in the profession who actually knows PCOS a bit more in-depth than most. Have you tried a HPT yet? xx

Welcome Suzi
I'm glad you found us

Clomid isn't the main treatment for PCOS. Its aim is to induce ovulation in anovulatory (not ovulating) patients. I have taken Clomid, but wasn't monitored. It was prescribed to me by my GP, although she shouldn't have because the surgery doesn't have the resources to monitor me properly. At the very minimum, I should have had a blood test at CD 21 to see if Clomid had worked (ie I'd ovulated). Most girls have earlier scans as well, to see if any follicles are ready to pop. Whatever happens, make sure you are going to be monitored!!

I'm sure I did ovulate the first month, and I believe I was pg (could also have been Clomid side-effects). However, HPTs didn't indicate pregnancy, so I began the second cycle when I started what I though was AF.

It works for a great many women, and I wish you luck, should you be prescribed it.

If you need more info about it, there are a number of great threads on mumsnet dedicated to ladies TTC with Clomid. xx

Hi All

Seems like we all have a lot in common with the flippin PCOS!

Thanks for all the tips and information. My GP did the blood tests but never followed it all up so I feel more prepared to go and chat to her about all this. My consultant did a laproscopy and said I had PCOS but discharged me from her list and sent me back to the GP. Its very frustrating.

Very interesting about the wee sticks thing though. The time I think I had an early MC nothing showed on the wee sticks even though I felt convinced I was PG. I remember how I felt the previous times I had been and it was exactly the same. I guess the hormone thing could well be true.

Good luck for Monday SuziBhoy Don't let them fob you off. I wish I'd been more
persistent now.

Take care all. Good to read these posts and know I'm not alone

Hello Suzibhoy et al, its been good to rad this thread for me. I have PCOS and am in my 2nd cycle with Clomid. 28, TTC for 18 months, PCOS symptoms varied but certainly not over weight.

I am on CD 30 or a usually 30-33 day cycle so getting my hopes up at this point. Clomid has been great for me as my consultant doesn't believe I was ovulating before and clearly now that I am (confirmed in recent blood test) that gives us a lot better chance of conception.

One thing my consultant did advise against was pee sticks, said they were rubbish and not to bother if you have PCOS so we might be back to the beginning of this thread again and hormone imbalance!

Good luck to all!

hi all...... this thread is great, its like you are in my head

have been ttc for 2 years, concieved once but it was ectopic.... have just found out i have pcos and have an appointment on monday to discuss treatment. Ive heard alot about clomid.... is this the most commen treatment?

how long after starting clomid did any of you notice a difference? excuse me for my questions a little anxious about monday.

Hi
Sorry for disappearing, been so busy the last few days.

Butterfly, Clwc described Metformin brilliantly for you. If you read some stories on verity (the PCOS website) it can be a wonder drug for some ladies, unfortunately I think because I am not overweight it doesn't work as well in me. Although last time I was on it it did start my cycles again (after no AF for a year!). I was having AF every 50-55 days which to me was fab but Clomid was added and I got pg.

Hope you are prescribed Metformin in July Clwc.

I think I will take the Norethisterone in mid June so I can hopefully take the Clomid in July some time and see what happens.

Keep in touch!

Hm. I don't know what's happened to SockThing. No doubt she'll be back soon.

Well, butterfly. It's good that you found us. Sorry about your early mc. I think I just had one too, but, obviously, HPTs showed no sign.

Metformin is a diabetes drug, not currently licensed for PCOS, but often the first step for treatment. It controls blood sugar levels in the body. Most overweight PCOSers have some level of insulin resistance, and this is what Metformin is prescribed to treat (after a fasting glucose blood test), with the main aim of avoiding the insulin resistance developing in to full-blown diabetes. Met should also help with the many unpleasant side-effects of insulin resistance, including weight gain, cystic acne (boils), dark skin patches, etc. askapatient.com provides details of side-effects of the drug on diabetes and PCOS patients.

I have an appointment with the gynae in July. I hope that she will be able to prescribe Met to me.

Have you tried Clomid, butterfly? x

Hi Sockthing.

What is Metformin? I've seen it mentioned a few times. When I looked it up it said it was a drug to treat diabetes and wasn't available to women with PCOS although it did help the condition. Is it something that can help conception when suffering with PCOS?

It does sound like many women are affected in different ways with PCOS. I have the facial hair and tendency to gain weight easily. Periods seems to be happening but not sure if I actually ovulate very often.

I hope all goes well with the scan. Its good to get an idea of what's going on in there and how things are looking. Hope it gives you some positive results.

Hi
Happy birthday clwc!
Hi Butterfly, its really interesting isn't it and PCOS is such a confusing condition as it affects women in different ways so we can't all understand what each other are going through. For me I am not overweight or suffer with excess hair, its spots and no periods for me!!

I went to see the consultant today and he said I should take Norethisterone to induce a period then Clomid. He is seeing me again in 3 months.

I am thinking of giving Metformin another month before taking the Norethisterone as it worked last time but did take a while. I am also going to have an ultrasound of my ovaries/pelvis to see what is going on in there too.

I'll keep you posted

Hi all.
It's been really interesting reading this thread as a fellow PCOS'r. I've being TTC for a year now and am wondering what to do next. I think I'll go to GP and ask more about hormones and TTC after reading all these comments. I've had blood tests done, one month I'd ovulated and one month I hadn't. Not sure what's going on with my insides!! Extra confusing factor is that I conceived very easily 3 times before (2 DC's aged 5 and 8 and one MC at 12 weeks) BUT with my previous DH. I am now wondering if it's more than just my PCOS thats the prob I also think I've had an early MC this time trying too as loads of symptoms and then a long 'cylce' with symptoms stopping just before AF. Cycle all over the place too. Its all sooooo confusing.

Sorry for the ramble! Good luck to you all.

Thanks. I'm not really looking forward to the 1st Anniversary of my 29th Birthday...

...Looking forward to the party though!

The specialist tried to fob me off with the pill (Dianette), but I read many cases of women who took it, only to come off it and develop worse PCOS symptoms than they had before. Also, I wanted to ovulate, and the pill doesn't do that for you.

Let me know how Monday goes. As this thread suggests, it may still have been a false -ve.

Hiya
Test was negative which I expected and I am not too bothered as I have only been on Met since early Feb and if I am honest I would prefer to get pregnant a bit later in the year for a baby next spring/summer to fit in with work (I know I will prob regret that when in 1 year's time I am still trying!).

At least I can see the consultant on Monday and tell him I am not pg and see if he wil u/s my ovaries/womb.

I was on Met to get pg, stopped it at 12 weeks and went back on the pill after my son was born as the pill was great for my cycles/skin everything. Came off the pill in Jan to start TTC again. May stay on Met after my next child is born (wishful thinking!)as I don't want to be on the pill again.

Sorry for rattling on! Hope you are well - and happy birthday for Monday!!

X

Hi SockThing,

Good to hear from you again. I thought Metformin was something you take for life. Shows what I know. I have an appt on the 3rd July. Perhaps they will let me try Met and give me some more info about it.

I just worked out that, if you are pg, you'll be about 11-12 weeks! Best of luck with your test tomorrow. xx

Hi again

I was on Metformin 2000mg last time and still had -ve tests for quite a while. I am on it again this time and on CD99 today!!! No symptoms, going to test tomorrow as its day 100!

See the specialist on Monday so will see what he thinks. I am going to ask for an ultrasound of my pelvis to see what is going on with my ovaries, if there is any activity at all.

Think he will prescribe Clomid too but I may wait and give the Metformin time to work for a few more months.

I'll let you know what happens after Monday

Hi again

I was on Metformin 2000mg last time and still had -ve tests for quite a while. I am on it again this time and on CD99 today!!! No symptoms, going to test tomorrow as its day 100!

See the specialist on Monday so will see what he thinks. I am going to ask for an ultrasound of my pelvis to see what is going on with my ovaries, if there is any activity at all.

Think he will prescribe Clomid too but I may wait and give the Metformin time to work for a few more months.

I'll let you know what happens after Monday

I hope everyone's well. Clwc. xx

bump

Thanks peacock.

Apparently, Metformin is supposed to control the hormone imbalance (assoc. with with PCOS) that happens after ovulation, therefore keeping hCG levels up. In many cases, Metformin is prescribed to try to avoid miscarriages caused by low hormone levels, aka 'inviable' pregnancies.

Have the ladies with these undetected pregnancies taken Metformin during the first trimester?

I'm off to see my doc tomorrow, and hope to be prescribed Metformin for this very reason. I'd also like a blood PT, as there's something very strange going on with my body and I don't know if it's just Clomid causing it, IYKWIM

Hey there.

I have been diagnosed with PCOS. ttc for years. Finally did rounds of Clomid and Progesterone. One to start, one to stop. Took Clomid, no AF, HPT was negtive, took progesterone to start, and when I didn't start, took another hpt at about 9 weeks, and fially got a positive result. First Dr. apt was after 10 weeks!!! Baby boy is 3 and doing good. Now we are ttc again, and taking clomid, Dr. said I did ovulate tis month. I am at w4d5. Still neg on the HPT. My Dr. said we will do a blood test on Monday, he is sure that I ovulated. I am also wondering and thinking that you are right about the PCOS and slow HCG levels.

bmstrawberry,

Sorry it was -ve, not least because you need an explanation! How did your appointment go? xx

Well the blood test was a BFN. I don't have the details on what my levels were because the nurse just left a message on my machine. Hopefully I will know more after my appointment tomorrow.

Hello all,

I have received a message from a girl who is good friends with someone in the know about all this. Apparently, an immunologist said that even mild PCOS can cause you to have low oestrogen (needed to ovulate), low hCG, low progesterone, and too much testosterone.

I would like this to be confirmed to me directly by a medical professional, but at least we know one doctor in the UK agrees

Eek. That's my birthday! You just reminded me that I won't be in my twenties anymore

I hope he can clear things up a bit for you. Perhaps he can give AF a boost in some way.

Ooh, the sun has just started shining...I'm off out to play

Hi
Great to see you all on here, I feel slightly more normal now!!

My last AF was end of Feb (induced by pill) then I stopped the pill and started Metformin. Nothing since then! I am on CD86!

I have a DS aged 5 and conceived him on Met so I know it can work for me. Last time I had sore boobs for about a week at around week 6(I know from counting back when I had a dating scan, had no idea I was pg) then they disappeared and after another 3 weeks I tested and had a really faint +ve.

I have done a few HPTs but I don't really think I am pg, I really want AF so I can then see if the Met gives me any kind of cycle. Last time I had a cycle of 50+ days but I did get pg.

Think I will get the consultant to test me and maybe ask for an us of my ovaries too. I see him on 18 May so only a few weeks! Maybe I will have had AF by then!

Thanks, Yankn. At least you've had some success. BFP at 13 and 14 DPO is quite normal, even for those without PCOS, but slow-rising hCG levels seem to be a bit of a theme amongst PCOSers. I don't think I'm just imagining it anymore. Perhaps it's just a 40% of cases event, perhaps it's more frequent. Let's see who else has a story to tell...

bmstrawberry, Many girls with PCOS take some form of progesterone (e.g. Noristherone) to bring on the bleed they need to start Clomid. Ask your doc for some if your blood test comes back negative.

My back has been all achy and I've had a few weird crampy pains in my stomach but nothing completely out of the ordinary. I have been waiting for this LONG AF to go away so I could start my first round of clomid.....and I'm still waiting. : 0

Another PCOSer here. Have gotten postive tests at 13dpo and 14dpo with my two pregnancies. First ended in miscarriage, with HCG levels being just at the low end of normal, rising very slowly and not doubling in the recommended amount of time. GP tested HCG because I noticed my main symptom (sore boobs) went away. There was a heartbeat at the scan at 6+6, but the sac was too small, which I found out is a good predictor of miscarriage. No idea if the HCG problem was related to PCOS or not.

Second pregnancy is at 23+2 and baby boy is absolutely fine.

I'm so glad you found us that way. Maybe more will come

Do you have other symptoms? Did you take Clomid?

Let's hope the Doc gets back to you tomorrow sometime...Oh, and fingers crossed that it's the news you want to hear

Ok, I was researching HCG levels and PCOS and just happened acrross you guys! Not much info on the net that's for sure.
I have PCOS and I'm on Metformin.....currently on CD55 with multiple negative home tests. The doc did a blood test yesterday so hopefully I will have some news to report to all of you by Friday or Monday at the latest!

I am TTC and started this thread during the 2ww. I am just as guilty as everyone else with symptom-spotting, but the meds (Clomid) also cause a wide range of confusing side-effects. AF arrived a few days ago.

I believe a blood test is more likely to detect even minimal amounts of hCG, but don't quote me on that. I'm no physician. When did you expect AF, SockThing? If it has been a while, I'd get your surgery nurse/GP or consultant to do a blood test. Epecially if you've had a lot of BFNs with HPTs. Explain to him/her what happened last time.

There was a poll done on soulcysters.com that asked how many DPO people had their BFP. Some were early and some were later. Perhaps it differs from PCOSer to PCOSer.

I didn't find anything interesting on the internet, can't be much research into it but I am convinced of it. Someone with PCOS I know from another website has found out she is 12 weeks pg despite numerous -ve tests over the last few months, she had tons of pg symptoms too.

I worry that as I didn't get ANY symptoms last time that I may be pg now and not know

Would a blood test show up pregnancy rather than a urine test?

Are you TTC clwc?

Anyone else?

Hello SockThing

Did you find anything interesting? Perhaps they need to try to detect a different substance in pregnant women with PCOS. Something not quite so hormone-related, perhaps?

Congrats for your perfect DS too

xx

Thanks, TattyCatty,

It is reassuring to hear stories of full-term PG with PCOS...and belated congrats on the birth of your DD

It started as a hunch, but the more I read, the more I see a correlation. I haven't found many medical sites that have put two and two together with this though. I hope more women come to this thread with their views, and hopefully a mid-wife and/or reproductive endocrinologist included!

xx

Hi
I had never heard of a link between HCG levels and PCOS but 5 years ago I got -ve HPTs for weeks and eventually got a very faint +ve, went for an "early" scan and was 15 weeks pg!

It has always bothered me that I never knew I was pg for weeks and weeks (I had no pg symptoms except no AF!). I always wondered why all the tests were -ve. I only kept taking them each week as it was such a long cycle and I wanted to get AF so I could take Clomid!

I had a dream pregnancy - until 26 weeks when my waters broke and I gave birth at 27 weeks! Nothing to do with PCOS though, I had an infection in my water I think?! DS is nearly 5 and absolutely perfect.

I am off to google this now as it has intrigued me!

I have never done any research into this but I have PCOS and my HcG levels were very slow to rise when I fell pregnant (after IUI). Got a positive HPT on day 14 after my treatment (which I guess is the equivalent of 14dpo - I don't ovulate naturally so don't have an idea of cycle length), but my first Beta HcG blood test was only 89 which my clinic thought was very low. My levels were then very slow to rise, barely doubling every 72 hours (most clinics look for them to double every 48 hours) so we were told to expect the worst and that the pregnancy wouldn't be viable. My slow to rise HcG levels are now 3 years old and playing with her Barbie dolls

There may be a link between slow rising HcG levels and PCOS (tempted to go and look myself now!), but there are lots of ladies on here with PCOS who like me have carried a baby to term, so please be reassured by that.

No worries, dancingqueeen

just wanted to apologise for sending a message so many times! didn't mean to!

Bump

Hello Catrin,

You may have.

On a couple of occasions before, I have felt as though I was pregnant, but it just ended up being another visit from AF. This time, I feel a bit different again, with nausea, headaches and a stronger cramping feeling. It was my first month of taking Clomid, and I'm now CD26. I had a negative HPT yesterday and now realise it was way too early for me to test.

Thank-you for your reply. Why did you keep testing? Missed AF? Let's see if anyone else had the same problem.

xx

Have no medical knowledge on this, but I had 7 negative HPTs from 5 weeks on and eventually got a positive at 7 1/2 weeks. Have PCOS.
Have I just confirmed your theory?

Gosh. Thanks dancingqueeen. lol
Are you interested to know too?

xx

just bumping for ypu. i don't have an answer but hope someone does

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just bumping for ypu. i don't have an answer but hope someone does

Bump

Hello all,

Apologies if this has been discussed previously.

I have been reading more and more about a link between PCOS and difficult to detect hCG levels during early pregnancy, making HPTs almost useless for many weeks.

Having been diagnosed with PCOS and hypothyroidism, I was once told, by a doctor, that different hormone disorders often go hand in hand. If that is the case, could it be that, even if a PCOS 'sufferer' were to become pregnant, not enough hCG would be produced to keep the pregnancy? Or has my thinking/knowledge gone to pot?

Does anyone have any thoughts on (1) the use of HPTs with PCOS and (2) the production of hCG when affected by PCOS?

That was long and my head's spinning. Hope I didn't just cure your insomnia!

xx