IUI with Clomid

(45 Posts)
Lynsy Sat 20-Sep-08 21:41:00


I am just after some advice really had our first consultation at the UCH hospital in London on Thursday and the doctor suggested we try IUI with clomid for 3 cycles, although he was very helpful and informative still came away having forgot to ask him some questions so thought I would see if anyone here can help me grin
Firstly I have had a day 21 test that shows I am ovualting so why do they use clomid it along with IUI, I thought this was given to people that are not ovualting?! does it hopefully improve our chances of success?
Secondly our reason for having assited conception is due to dp's poor sperm, he has morphology of 1%, and although I know they wash the sperm and put back the best ones, with dp's being so deformed I wasn't sure that IUI would work?

Any advice would be great.x

Lynsy Sun 21-Sep-08 09:01:51


QOD Sun 21-Sep-08 09:18:13

Hi, the clomid is to give you best chance, make sure you deffo ovulate and perhaps to see if you can produce 2 eggs, give you a better chance.
SUrely they just put back in the good ones?
IUI is basically a very very low cost version of IVF that works for lots of people - they do it to give you a extra chance.
I had it, 2 friends had it, both got pregnant 1st time! I had 4 failed cycles (never even got so far as them actually putting sperm back in)
Best of luck!

Lynsy Mon 22-Sep-08 12:00:54

Thanks very much for you reply, was hoping that the clomid would increase our chances of success.
If anyone else has any other advice or success stories then it would be lovely to hear them.

RealityGap Mon 22-Sep-08 12:15:17


Using clomid seems to improve the chances of IUI working. By doing IUI your husbands sperm is put right where it needs to go giving it the best chance to get to your eggs.

I got pregnant on our 3rd IUI - but sadly M/Cd so hang on in there it can work

Hoping you get a BFP soon

gillydaffodil Tue 23-Sep-08 08:16:52

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Lynsy Tue 23-Sep-08 09:40:24

Morning Gillydaffodil,

Thankyou so much for your detailed reply, and explaining the process to me, I am sure like most people I never thought we would be going down this route, so there is so much to learn and understand.

I am due to start at the end of Ocotber as I am having a laparoscopy under the NHS next Tuessay, so the dr suggested to go ahead with that, make sure that I am all fine, give my body a month to recover and start after that- very excited that at last we have a date and that something is happening but also very nervous and trying not to set myself up for a fall - going to try and just go with it, and if it doesn't work, then move on to IVF, easier said than done I imagine!

You say they don't do IVF at the UCH, but all the information they have sent me doesn't say they don't - am I missing something grin

I really hope that the IUI works out for you and you get your BFP soon.

I would be so lost without the lovely ladies on mumsnet - Thankyou.

bamboostalks Tue 23-Sep-08 09:43:53

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gillydaffodil Tue 23-Sep-08 10:09:07

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gillydaffodil Tue 23-Sep-08 10:14:12

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hobnobs Tue 23-Sep-08 10:27:08

Big wave to Gilly grin.

Lynsey - I had my IUI with clomid at the ACU at UCH (the private one in the New Wing of the Eastment Dental hospital) at the end of July. As Gilly said, I was successful - to my utter amazement (I am 39) - on my first attempt and am now just over 10 weeks. I had my second scan there last week and have now been discharged back to my GP / midwife.

In our case, we had unexplained fertility - I knew there was no problem ovulating or with DH but maybe the extra egg just increased our chances. The procedure there was very similar to what Gilly outlined at the NHS hospital just round the corner though they didn't need to trigger ovulation with me, but that might have been because I had a positive on an Ovulation Predictor Kit which not everyone gets and I don't think my follicles got as large as hers.

When we had our initial consultation, the doctor said that they had a policy of trying the least invasive treatment first which suited me, though I'm aware that the success rates are less than for IVF. From a financial point of view, it's also a lot cheaper!

Good luck smile

bamboostalks Tue 23-Sep-08 14:22:40

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gillydaffodil Tue 23-Sep-08 14:27:41

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Lynsy Tue 23-Sep-08 17:21:48

ah thanks girls for your replies and congratulations Hobnobs, such lovely news to hear from someone that has been through exactly the same thing - I hope you have a happy and healthy pregnancy.

Your so right Gilly when you say about focusing your thoughts, feel so much more relaxed about it all now and has taken the pressure of ttc, has made it more how it should be - enjoyable smile, although I know there is still a rollercoaster ahead of us.

Didn't realise there were 2 UCH's we are under the ACU at UCH.

Bamboostalks when are you due to start your first cycle? I feel exactly the same way as you, so many worries and thoughts going through my mind, but I am sure we will both be fine and will keep my fingers crossed that it all goes well for you and you get your BFP.

hobnobs Tue 23-Sep-08 18:42:23

Bamboostalks - I didn't have any side effects from the Clomid either (or not that I noticed!) Like Gilly, it lengthened my usual 26 day cycle by 1-2 days. I'd also been taking my temperature and not sure if it was related, but for the first time, I didn't get a clear shift after ovulation so Fertility Friend didn't think I'd ovulated! shock

Lynsey - thanks for the good wishes. Still a bit nervous (and DH even more so) though hopefully I'll be able to relax a bit once I have the dating scan in the next few weeks and finish the first trimester.

Wishing you both all the best. smile

bamboostalks Fri 26-Sep-08 19:28:37

Hi Lynsy, will start clomid on Monday. When are you about to start? Did you see Mr Serhal? Shall we keep each other company? Am desperate for this to work...obviously!! I also had a lap and dye on the NHS, have had actually.It was fine, though had terrible shoulder pain afterwards, tummy was nothing in comparison. Good Luck with it.

Lynsy Fri 26-Sep-08 21:26:25

Hi Bamboostalks,

I am hoping to start my first cycle as soon as my period arives after the laparoscopy so should be about the 20th Ocotber.
We saw Dr Massimo Ranieri, very nice Italian Man.

Would be lovely to keep each other company and share how it is all going, obviousley you are starting before me so would nice to keep in touch and hear how it is going for you, and how you are finding it all.

I heard that shoulder pain was a common after effect of a laparoscopy - Did you just take strong pain killers? How long did the pain last? - I am starting to get nervous about it now!

Good luck for Monday I Imagine you are excited and nervous all rolled in to one - heres hoping it's first time lucky for both of us.

bamboostalks Fri 26-Sep-08 21:46:38

Didn't mean for you to get nervous! Apparently it is the anathestic gas escaping, the pain killers didn't help with that tbh. A minority actually suffer that though so do not worry. I was actually on clomid before (long story) through the NHS but I developed really bad cysts on it so treatment was discontinued but it has been recommended again so we will see. That is why I am apprehensive.

Lynsy Fri 26-Sep-08 22:07:05

No don't worry you didn't get me nervous at all, been feeling that way for the last few days, just want it over and done with smile.

No wonder your apprehensive about taking clomid again, and what with it being along side IUI which is a whole new thing for you it's only natural to feel that way. I am sure they will keep a close eye on you especially given your past experience, xx

JenJen79 Wed 01-Oct-08 22:10:23

Hi, I had my first IUI done with Clomid and Ovitrelle on saturday 20th. Will find out if im preggie this saturday. I can't wait! it has been the longest wait ever! This is my first attempt and am hoping all goes well. Like you it was quite overwhelming. Im with the Lister Fertility, they are great also. I had very irregular periods, so they started me on provera to induce my period, then clomid to produce the follicles. When the folliclles got to 18mm, I was then told to take ovitrelle, this induced ovulation and then 36 hours later IUI! so fingers cross! My husband and I dont have any major problems, just me and my irregular periods! However, im not feeling any preggie symptons, is there anyone thats gone through the IUI and are on the 2WW with any symptoms ??

Lynsy Fri 03-Oct-08 20:15:51

Bamboostalks, just checking in to see how you are getting on with the clomid - I hope it's all going well.
jenjen, good luck with testing tomorrow,I have no advice to give about 2ww symptoms as I haven't started yet, but fingers crossed for you.


been taking clomid 50mg for 5mths now, fell preg 1st cycle but m/c early on. tried for over a year but nothing happened, have early pcos, have no one to talk to about this. as i am only 23 and have a 3 year old it was a hugh shock for me and my husband. hate doing preg tests nearly every mth.


I have PCOS as well.

Are you under the care of a gynae at a subfertility unit at present, if not you should be. This is a condition that should not be messed around with by GPs.

www.verity-pcos.org.uk is a website that you may find helpful as it is specifically for women with PCOS.

HTH, any other questions just ask


KoiMaloy Sun 09-Nov-08 15:45:46


Does anyone know if it's possible to do IUI without clomid? I'm paranoid about multiple birth risk surely this is increased if i produce 3 eggs! Our problem appears to be with d's reduced motility. I'm ovulating normally hoping this enough for IUI.

Due to start our first cycle in 2 weeks so this is all v.new to me.

So pleased to have found mumsnet!



gillydaffodil Sun 09-Nov-08 19:10:36

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Issy42 Sun 09-Nov-08 19:46:43

Koi - I had 5 cycles of IUI without clomid and only had the ovitrelle when there was a risk of ov on a Sunday (when my clinic doesn't treat). My first cycle worked but mc'd at just under 5 weeks. Like you I was concerned about multiples, but I've finally given in and am now on my second clomid cycle. Really wish I'd taken it earlier now - feel like I wasted so much money in not doing so. Mind you I've got to the point where I think twins is better than none! Good luck!

poppy75 Mon 10-Nov-08 17:58:26

Hello Guys - great to read all your messages regarding IUI

I've been ttc for three years with unexplained infertility and 1 MC (2.5 years ago).

My consultant has suggested IUI or IVF but as my PCT doesn't offer any fertility treatment if you are under 36 I will have to pay for it sad sad

So have booked an appointment in Jan at a local fertility clinic. DH is not keen to have assisted conception but I've convinced him to try IUI (it is also alot cheaper and we can afford it compared to IVF).

Do you know what I should look for in a clinic??

Was wondering if it would be wise to get a second opinion on the NHS?? As had ultrasound, HSG to check tubes and 4 months of clomid under other consultant without success sad. DH thinks it will be a waste of time but not sure if I should try as it is a lot of money to shell out - all advice welcomed!!!

Issy42 Mon 10-Nov-08 21:36:20

Hi Poppy. I would get a second opinion, just in case it makes a difference. Also can you pay for treatment at your nearest nhs clinic? That's what I do and it's only £415 for IUI with partner sperm, whereas others on here pay £1600 a time. Had to be referred by my GP. Good luck!

poppy75 Wed 12-Nov-08 17:56:01

Hi Issy - thanks I think what I'd do is book an appointment with my GP. I thought it was strange that my consultant didn't give me an options of where I could go for private treatment which made me a little suspicious. As I work in the NHS I always have to give patients a few options as I can't directly refer a patient to a certain service which they have to pay for! smile The joys of ttc heh!

poppy75 Wed 12-Nov-08 17:56:01

Hi Issy - thanks I think what I'd do is book an appointment with my GP. I thought it was strange that my consultant didn't give me an options of where I could go for private treatment which made me a little suspicious. As I work in the NHS I always have to give patients a few options as I can't directly refer a patient to a certain service which they have to pay for! smile The joys of ttc heh!

bamboostalks Fri 21-Nov-08 21:00:33

Just wondering how any of you guys are going?
I am waiting to start my third round of IUI/Clomid, on cd 30 did test on cd28 and it was - so just waiting for AF now. It has been 18 days since the IUI so I am getting impatient. I think that I just want to move onto IVF really.

Lynsy Sat 22-Nov-08 21:54:13

Hello Girls

Long time no speak.

BB so sorry to hear that the IUI has been unsucessful so far, will this be your last round of IUI before you start IVF?

We unfortunatley haven't even got that far. My laparoscopy found that I have severe endo which is blocking my right fallopian tube. This came as somewhat of a shock as I have never suffered any symptoms. I am now currently on 3 months worth of injections to down regulate my body and put it into a menopausal state so that the endo dries out, and I am due to have another laparoscopy done at the end of January, so our ttc plans are now on hold sad. On the upside after 3 months of lifestyle changes and copious amounts of vitamins dp's sperm is now completley normal and gyne has said that after laparoscopy in January should be no reason why we can't fall preganant naturally smile.

Hello to everyone else hope things are going.

Lynsy Sat 22-Nov-08 21:55:25

that meant to say, hope things are going well.x

lisa114 Mon 19-Jan-09 18:14:18

Hi all
I don't now whether anyone can offer any advice. Just started my first cycle of clomid last week prior to IUI, i went for a scan today and there were 8 fluid sacks which the nurse said because of the size were eggs and we couldnt have IUI this cycle as there were to many eggs she also told me to use contrception this month as there is a major risk of a multiple birth!? Should i use contraception or just see what happens? hmm

sissy0928 Wed 11-Feb-09 23:02:13

I would go for it, but it depends on how old you are and your level of urgency. Of course always speak with a professional first. I'm 39 and took 50mg Chlomid this past cycle (I had 2 eggs)and had IUI 10 days ago. I'm taking a blood test this saturday but it's all I can think about. At my age I'm scared it won't happen for me. Good luck to you!

This thread is from long time ago but wanted to wave at you all if you are all here and say I am starting iui with clomid next month at uch acu (now crgh) and was searching for info and found this - all very helpful.

crystalz Mon 06-Sep-10 21:39:17

Can anyone please help. My friend has been TTc for several years she has just been told her eggs don't become mature.Therefore, she needs to go on IUI. She is very nervous and worried. Can anyone please share similar stories?

pixiness Wed 02-Nov-11 21:04:21

has any ! had multiple births with clomid and iui treatment. we are about to start this and want to know what the chances are

highlove Wed 02-Nov-11 21:17:06

pixiness - chance of multiple pg with clomid is about 10%, massively lower, like less than 1%, of having more than two. But, not sure if the IUI makes a difference. I wouldn't think so - I do know that a natural IUI cycle has no more a chance of multiples than an ordinary pg (obviously, there's only one egg!)


pixiness Thu 03-Nov-11 02:14:10

i hav unexplained fertility and just had a laporoscpy and tube patency, my partner has swimmer problems so we are heading for iui with clomid or other fertility drugs, i hav aunts on my dads side who are twins, my dad and his new young girlfriend just had twins and my partner has twin brothers. any ideas how the fertility drugs and iui mite work out with all that?? i wouldnt mind twins but dont want to be octomum
has any1 had any multiple births in the clomid, iui treatments? much grateful for all answers

pixiness Thu 03-Nov-11 02:23:39

and can any1 please explain the whole iui with clomit, proccedure to me, what u hav to do and take and times amounts and cycles please. new mom hoping to be and knows nothing at 41 years old,gratful to all uladies out there

pixiness Thu 03-Nov-11 02:30:47

hi sissy0928. can uexplain the iui process with clomid, how it works, the chances and y do u not think it will work for ur age\/ im 41 and just heading down this route, all advice welcome

Scrummybumb Thu 03-Nov-11 11:01:11

Hi pixiness. Here's a link to one study on the subject www.advancedfertility.com/revmultiplescoh.htm. I just started my first Clomid/IUI cycle.

I had blood tests at the start of the cycle to confirm hormone levels to see if ok to start. Then started Clomid on day 2. Took 100mg (two tablets once a day) for 5 days. Due for a scan tomorrow to confirm how I've responded. If there are too many follicles, the cycle will be cancelled. So you always have a choice.

The chances have a lot to do with your hormone levels at the time, not just age. Some women in their forties are still very fertile.

best of luck with your journey. If you want to come and join others going through same thing, you can find us on the Assisted Conception thread. Feel free to join us.

pixiness Thu 03-Nov-11 12:15:45

thank you very much, i will join on the other thread too, i may sound stupid but wot exactly do the follicles mean? sorry, iv not had much info from my consultant on anything and am finding out most off the proceedures and info online from u ladies

Scrummybumb Sun 06-Nov-11 13:43:08

Follicle is the shell that holds the egg (aka oocyte). I too have found out most things either here or other sites online. I have read a few books too. It's worth spending som time to read though a few of them. Taking charge of your fertility is a good start for basics. There are plenty books and theories on what works, so you just need to find that you agree with.

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