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Good luckginger !

Hi all!

My scan went well thanks. My lining was 10mm which they seemed happy with. We signed the consent forms, and decided on our thaw plan (basically thaw one, then if it does not survive, thaw the other one) and to have one put back. We have 2 blasts, one day 5, one day 6. We also paid our dues, so are feeling a lot poorer now! I am now on the progesterone pessaries, 2 a day, and am looking forward to the embryo transfer next Tues! Feeling really quite excited now, and really starting to believe this one could be it!

Big hugs to you all, and will give another update after my transfer on Tues. I am off to a wedding this weekend, so last chance to let my hair down a bit (but not too much obviously).

DSB

Hi pocket

Movie was good! Just what I needed some girley time and a two hour switch off :-) glad i didn't pressure myself to read the book before going, as I might have been disspointed!

No worries Jewcy - haha. I keep thinking we do have the donor ones back, as wed got our mind so fixed on that's the way it would have to be!

Lots of exciting work distractions this week so 6 days have passed quickly so far :-) 4 days to go - roll on Tuesday!!! Fortunately i have been able to keep my feet up whilst tapping away on the laptop.

Have a great bank holiday weekend everyone if I don't check in.

Juicy sounds like you're making good progress. Hang in there. Btw I'm 33+6 with what was originally a 5 day blasto... They picked the best one (well two in fact) and the theory is that they do better inside than out (if you know what I mean) and therefore the odds are good.

Ginger hon, hope scan yesterday went well. What's the update?

Lucky DSB. How was the movie?

Hope everyone is doing well

All together now, "don't stop beleiving"
x

Oh, crickey, Lucky, I messed up my last post. Of course I know your husband doesn't mind donor sperm 'cos you had half-and-half tested this time. D'OH!

Thanks motorcycle mama - if there was a degree if take it! I'd also consider Ivf drug dispensing haha!! Good luck with getting stated.

Juicy pear like the name change :-) I'm so fortunate to have a husband completely on board - he was set for us using donor sperm this time and hence we did. I too feel open to donor eggs. The relief is he didn't give me a look of thunder when I mentioned more Ivf if needed!!! Eeeeek!
Glad you mock cycle is going well :-)

But in this forums true ethos - I won't need either as I won't stop believing that this is going to work :-)))

Gingernut - hope the scan went well?

Waves to all

Off to the cinema to see the great gadsby tonight for some girley fun

have a good evening all

xxx

Hi, Jewcy here, just had a slight name change to fend off repeated questions about Judaism

Lucky, I am boggled by your report, but happily so; I have to pinch myself when I think how fortunate I am to be having the embryoscope. If this doesn't work for you I would definitely go for donor eggs and - depending on your DH's resistance - donor sperm. It also depends how much money you can afford to keep chucking at your own DNA, I suppose. I had one chance at this and didn't want to waste it on my own eggs, despite having an AMH of 5.5 and FSH of 6.5. It's all down to age for me, I'm afraid (almost 42).

Motor, yes, I, too, am bamboozled by this whole protocol. Buzzy, on our other thread, also downregged for her DE IVF. Can't wait for these gloopy pessaries to piss off..

Don't stop believing!

It is amazing what they can do with this embryo monitoring stuff isn't it?
lucky you should be awarded a degree in embryo development at the end of all this! Sounds like it has all gone wonderfully well, congrats, and DSB indeed!
jewcy I am getting increasingly alarmed that although we are essentially going through the same process, our treatment seems to be totally different ! I think that I will be downregging, and I won't start pessaries until the day before the donor's egg collection. Maybe it is because you have a mock cycle?

Ginger - good luck for the scan today , in terms of how many to put back, weve always gone for 2 - doubles your chances at least.

Jewcy - that's great news and not long until the 26th now

Motorcycle mama - thank you - yes bloomin amazed and happy :-)

Sunny - so good to hear from you. Hope your little twins are getting on just find in their snug home. Are you weaned off any meds yet or does the joys of the daily cocktail still continue?

Pocket - thanks sweetie, I know to not stop believing from your journey alone missie :-)

So - we heard from dr v last night, our embryos that remained in the incubator under embryoscopy continued to develop.

With the donor sperm we had 3 that reached blastocyst - 1 x AA (great quality) 1x AB. 1X AB (pretty great quality) then 3 that reached molar stage just before blastocyst. My hubby's 3rd embie reached molar. Now if wed been selecting a day 6 transfer the two donors would have been the DEFINATE choice but because of the mirracles of embryoscopy they had seen that despite them looking great blastocyst, by day 3 all of the donor embryos had multi nuclearation ( so hence genetically damaged and non viable for pregnancy!) my hubby's 3rd had this too!

So although this is really not the news we wanted to hear about my eggs, it just goes to show that this is such a miracle for us that out of 19 eggs, these two of my hubby's embies had the right sperm and right egg put together completely by chance and we have two genetically normal (or as far as they can tell from the observations) put back.

We got the videos of our embryo development though yesterday and we can now watch the first 6 days of all of the embies life! Crazy, just crazy!! Wouldnt that make an unusual show and tell to our future child if these embies decide to stick around!!!

Can I ask for you ladies who have had egg factors - had anyone been able to tell you why? I asked dr v last night, is it my age (35) is it that I've had 5 rounds of Ivf and eggs forced? Is it she stimulated me harder this time with increased menopur, have I always had it? Trying not to dwell on it too much at this stage however ive basically just had the news that my eggs are a big part of the the problem when they have always blamed the sperm. Whilst the sperm def. hadn't been great, dr v said with this pattern the eggs are making more of the difference as eggs have the chance to repair some sperm damage if the eggs are good.

It leaves us thinking IF this dosent work (and we are so hoping for our miracle) do we need an egg donor with my hubby's sperm or an egg and a sperm donor. Be interested in others egg stories please lovely ladies.

Dr v said biopsying eggs is pretty useful really as it only tells you about that 1 egg and all others could be different in that cycle and different again in further cycles!!! Dosent help me though to understand and whether to risk using mine again when you get the needle in a haystack chance.

In the meantime I promise I will not stop believing xxxxx

wonderful news Lucky on ET. I am so impressed by your clinic's advances and moving with the times. I've watched all of the recent news.media about these advances with interest. I do tend to feel it's these clinics that try these new things out, forge ahead or whatever that make a difference to this fertility business. I have everything crossed for you!

ginger good luck for Wed's scan. I know you are anxious for it. Let us know how you get on. And jewcy not long now for you as well.

Go ladies go!

And don't stop believing okay!

oxox

Lucky, thank you for sharing your insight and experiences, very interesting about the progesterone dose. Yes, I'm on 200mg Utrogestan twice a day but this is my mock cycle and the progesterone is simply to thicken my womb lining I presume. Because I am using an egg donor I don't think the drug regimen is anywhere near as intense or uncomfortable as for 'normal' IVFers using their own eggs. For example, I do not need to downreg or do any stimming. After the embryos have been implanted I will be given a new set of drugs to fly home with.

The pessaries are absolutely fine! No leaking or discomfort

Ginger, my scan went well: 'beautiful uterus lining' and 'terrific' ovaries

Transfer cycle begins 26th May.

Don't Stop Believing xx

Great news lucky - couldn't be better - congrats!!

Lucky Woo Hoo! I am really pleased for you! Go embies, go!!

Our embies are frozen, so they have already been in the embryoscope and monitored to blastocyst stage. I have 2 but don't know whether they will want to put back one or two when it comes to it. I am currently on day 8 of my medication, getting impatient for my scan on Wed to see how everything is going.

Jewcy I hope you are getting ok with the pessaries. I also ended up taking them rectally last cycle as I had spotting too, and it was less gunky this way (though not very comfortable to put in.. ) Let us know how your scan goes.

Pocket lovely to hear about your 3D scan and lovely picture of her feet! I bet you can't wait to meet her now!

Beginning lovely to hear from you and how fab that you and pocket are so close with your dates. I hope all goes swimmingly for you for the next 8 weeks.

Hugs to all.

DSB

Hi Jewcy

Gobsmacked indeed! Take a look at Care's recent interview on BBC
http://www.bbc.co.uk/news/health-22562146

I would keep a look out on the forums to see what other clinics are saying, but I they have said to us, that because this information is now available to them in the first 24 hours, it makes day 3 transfers much more viable. The decision made for us was also based on the fact that we only had 3 of my hubby's so they didn't want to risk them not reaching blastocyst. However Dr Venkat also said to us, that as expected embryos do develop differently in artificial conditions as therefore fragmentation is much more likely during IVF rounds, therefore getting them back in the natural environment as soon as is always more preferable.

We have always waited to blast. each round, (although last round we did have a day 3 and a day 5 transfer).

One other thing to note from your pessaries, is this your first round Jewcy? Hence have you used pessaries before. Care always use Utrogestan which I believe are 200mg strength - and every time I spotted. My clinic now even thinks the time we did achieve a euphloid blastocyst (ie genitally fine) and tested positive for 4 days - we lost is as my progesterone levels weren't high enough.

My clinic always use Cyclogest - 400mg - to give you an idea Im on 2x 400mg a day and also I am on 100 of gestone injection. My consultant says that you should be able to prevent ever spotting, if you get the progesterone levels right, it dosen't mean the embryo will always embed still, but you would never risk loosing it due to low progesterone. We strongly feel we lost ours embryo's on that round with Care because they wouldn't increase or change my dose.

Also I always felt that pessaries irritated me. My clinic always suggest rectally now and never vaginally - especially pre and post collection and transfer.

Just some thoughts and I dont want to scare anyone doing it differently, but experience has told me these are quite factual observations.

So Test day is 28th May by blood and 30th May by urine :-)

Lucky, what an incredible turn of events, you must be gobsmacked and thrilled in equal measure. Well done, old girl, and well done hubby's sperm! I am now worried because my clinic in the Czech uses the embryoscope but also takes the embryos to day-5 blastos. Are you saying that this is unnecessary? What are your thoughts?

Had my scan today and all is well: 'beautiful' uterus and 'terrific' ovaries. Oh yeah? So why the feck am I not pregnant, then?

Started Utrogestan vaginal pessaries today, too

Lucky, when is OTD?

Hi Jewcy

Well we have had two put back and would you believe those two are my hubbie's - ecstatic!!

Of all our embryos - one of Hubby's was the best of the them all.

A grade b - 8 cell (nearly a grade a) but the embryologist is a very tough judge in this clinic apparently.

The second put back of my hubby's was a grade d 8 cell - so a bit on the scraggy side but he told us that he has had healthy twins from just one embryo put back like this, which divided.

So what a journey! Now to rest rest rest, pray, pray, pray.

If it wasn't for the release of this embryoscopy talked about in the press today, we would never know what we know from today! Lets hope its fate!

It's taken this to show thy there are some egg factors in our case, where we've always been led to believe thy it was only sperm factors. We paid for so many extras on our last round array CGH, IMSI microscope for sperm selection etc etc. but this embryoscopy has been the MOST informative. £500.00 with our clinic so it appears we may have got a bargain too.

Taking plenty of progesterone to hold onto these previous beans.

Keep you posted and thanks all for all your good wishes.

Ginger and juicy I hope you both get off to a flying start :-) do ask about embryoscopy ginger if you can.

It would be a miracle if we could show our child the news paper cutting from today and say this is what made the difference and fate announced this on the week of our cycle ;-)

It was a day 3 transfer by the way and I would suspect that with this technology we will see more day 3 transfers as no need to decide by the naked eye and wait for blastocyst.

All our previous embryos have reached blastocysts and all our embryos today look like pretty perfect embryos by appearance today - but clearly many have genetic difficulties and would never implant! Thank god for this science!!!

Xxx

Lucky, how did ET go? Which embies did they use and how many days were they? Did you pay for the embryo monitoring? We are having it, too, and are very excited at the results so far that have been reported. It's £750 in the UK for the embryoscope but we are paying £420 for it in the Czech. Hooray!

Take courage in the embryologists decision, Lucky, you've benefited from cutting edge technology there.

Hi ladies really quick check in;

Going for embryo transfer this afternoon! Bit bit of a shock yesterday as a new monitoring video system used on the embryos reveals there may be some possible egg factor problems which have been also contributing to previous difficulties :-( not what we wanted to hear at all. This couldn't be picked up before in our previous cycles because it was evaluated all be the naked eye! (Ironically its all in the news today - so in one way thank god we're getting to use this method- cutting edge stuff!)

Our journey dosent seem to get any easier and what's been given on the one hand with this cycle feels like it has been taken away with the other
:-(

But better to know than not to know. Not all embryos are affected so we just have to hope they've put the right egg with the right sperm. As of last night one of my hubbies embryos was unaffected and some of the donors. Equally all could stand a chance of repair as its so early on.

Glad we had some time to take on board this info - had a real good cry last night but feeling upbeat and optimistic again this morning.

So fingers crossed and we are praying for our little miracle today. Keep everything crossed for us today. Transfer at 2pm xxx

Thanks, Ginger, the drugs turned up yesterday and I start progesterone pessaries tomorrow morning - just before my scan!

Pocket, great news about the scan and thanks for the tip-off.

Beginning, good luck with the rest of your pregnancy.

Lucky, good news about the embies? Come give us an update.

Waves to Frosticle.

Shorter sperm donor , not sure what a shorted one is! :-)

Pocket how funny our due dates are so close. I'm feeling good but looking forward to finishing work and feel like I am gonna run out of space for this baby, turns out I should have picked the shorted sperm donor as this baby seems to have been big from the off with especially long legs! :-) x

Lucky woop woop. Fingers crossed that this good luck continues...

Beginning you're exactly one week behind me, amazing hey? How are you feeling?

Ginger you're on your way. Rest and be kind to yourself, you need to be fighting fit next week!

Waves and DSB vibes to Frosticle, Jewcy, Expat and MotorcycleMama

Well the little one was at least facing the right way for the second 3D scan, but kept her arms and feet in front of her face - so we only got one piccie. And that's of her feet. But what lovely feet they are! She's keeping us guessing until she arrives.

Btw, if any of you ever considering a 3D scan, they're best done 27-32 weeks (we're a bit late) and I've been told that its really hit and miss. All those lovely piccies you see of beautiful clear baby faces are actually rather rare... and often due to too much fluid. They are expensive so thought a little heads up was in order - given the money we've all spend on treatment...

DSB
x

Just wanted say to Lucky it only takes one egg...or in Sunnys case two eggs! It is a bit scary how many you start with though and how many actually end up good.
I am 32 weeks tomorrow crazy to think bubba will be here within the next 8 weeks (apparently they don't let IVF babies go over their due dates)
Good luck everyone else
Don't stop believing!

Hi all

Just a quick stop in, thanks for all your good wishes.

Yes so pleased with yesterday's collection and results.

heard from clinic today

3 out of 6 fertilised of ours - this is good still because we have to take into account its frozen sperm and testicular they say.

6 out of 8 of the donors fertilised. Again we have to take into account that the sperm was frozen, where as usually our fertilisation rates have been very very high (90%) based on fresh sperm.

All in all Dr Venkat is happy .

Thank god we had a lt of eggs though hey, as you often seem to etch the numbers diminish!

Next update tomorrow

Expat, juicy and ginger - the very best of luck I shall be back on line rooting for you.

Pocket I so hope you got to see your little girl at her best today :-)

Hugs to all and sort if I've missed anyone tonight xxx

Lucky such fab news re the number of eggs and also having some viable sperm from your DH to use on some of the eggs! I have all my fingers and toes crossed for you!

Expat good luck with the upcoming cycle. I'm sure you'll be ok with the self injecting, it seems scary at first but you soon get past that and it is the beginning of your journey, so go for it!

Jewcy I hope you are getting on ok with the drugs, and good luck with the scan on 18th.

Hello to Motor and also hugs to Frosticle, I hope you are doing ok sweetie.

AFM, I am on day 5 of my HRT and Baby Aspirin (along with the Folic Acid and Vits B12 and B6). Tomorrow I start my steroids and my scan is booked for next wed. I have also had my bill for the FET too, so need to ring up and get that paid as I don't want any delays! So far I am feeling ok, just extremely tired, but I'm not sure if that is the drugs or just me!

Waves to everyone else.

DSB